Hispanics, built environment & metabolic syndrome

西班牙裔、建筑环境

• 批准号: 7579668
• 负责人: Jose Szapocznik
• 金额: $ 8.57万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-15 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7579668
• 关键词: Address; Affect; Age; Behavior; Behavioral; Biological; Biological Factors; Biology; Calories; Communities; Complex; Condition; County; Cuba; Devices; Diabetes Mellitus; Diet; Environment; Equation; Figs - dietary; Growth; Health; Hispanics; Immigrant; Individual; Inflammation; Insulin Resistance; Life Style; Longitudinal Studies; Measures; Mediating; Metabolic syndrome; Methodology; Modeling; Natural experiment; Nature; Neighborhoods; Obesity; Outcome; Outcome Study; Participant; Pathway interactions; Patient Self-Report; Physical activity; Population; Publishing; Rate; Relative (related person); Resistance; Sampling; Selection Bias; Social Environment; Testing; Time; Weight Gain; age group; base; day; energy balance; prospective; radius bone structure; residence

In a prospective longitudinal study, it is hypothesized that the built environment's walkability will impact the social environment's collective efficacy, and that these environmental variables together will influence physical activity. Controlling for diet, physical activity is hypothesized to predict adiposity, inflammation, and nsulin resistance; and these in turn will predict progression in metabolic syndrome indicators. While these ¿elationships have been tested separately, this application proposes an integrated and interdisciplinary test of the relationship among these variables. Hispanic immigrants are selected for this study because Hispanics have disproportionately high rates of diabetes. Moreover, for very recent immigrants, weight increases rapidly as a function of time in the US.The study proposes to explore trajectories of cultural change - and their impact on diet and physical activity - as a mechanism by which 'time in the US' may bring about its deleterious health outcome for this population. A sample is proposed that is uniquely suited to investigate this phenomenon in Hispanics, as well as the impact of the built environment on physical activity and health outcomes: Cuban immigrants within 90 days of arrival to the US. This sample addresses in part the self- selection bias that characterizes most built environment studies, because, when these individuals arrive in Miami-Dade County, they typically move to a neighborhood not of their choosing. Therefore, an ideal natural experiment occurs in which a naive sample in relation to non-walkable environments is distributed across a variety of walkability conditions. Participants will be 390, 30-45 year-old recent immigrants who do not meet criteria for metabolic syndrome. Built environment's walkability will be assessed through self-reports, and objectively using the .25 mile radius surrounding the participant's residence. Participants will be assessed on self-reported measures of collective efficacy, physical activity, diet, and biculturation, and objective measures of physical activity, adiposity, inflammation, insulin resistance, and metabolic syndrome indicators. Variables in the primary analyses will be continuously distributed. Growth curves will be estimated using growth curve methodology in a structural equations framework using Mplus 3.

在一项前瞻性纵向研究中，假设建筑环境的可步行性将影响 社会环境的集体效率，这些环境变量将共同影响 体育锻炼。控制饮食，假设体育锻炼以预测肥胖，感染和 Nsulin耐药性；这些反过来将预测代谢综合征指标的进展。而这些 »策略已分别测试，该应用程序提出了一项集成和跨学科测试 这些变量之间的关系。西班牙裔移民被选为这项研究，因为西班牙裔 糖尿病率不成比例。此外，对于最近的移民，体重增加 在美国的时间函数迅速。 它们对饮食和体育锻炼的影响 - 作为“美国时间”可能带来的机制 该人群有害健康结果。提出了一个独特适合调查的样本 这种现象在西班牙裔中，以及建筑环境对体育锻炼和健康的影响 结果：到达美国后90天内的古巴移民。该示例在某种程度上解决了自我 特征大多数建筑环境研究的选择偏见，因为当这些人到达时 迈阿密 - 戴德县，他们通常搬到他们选择的社区。因此，理想的自然 实验发生在其中，与不可行的环境相关的幼稚样本分布在一个 步行条件多样。参与者将是390、30-45岁的年轻人，他们没有见面 代谢综合征的标准。建筑环境的可步行性将通过自我报告进行评估，并且 客观地使用参与者住所周围的.25英里半径。参与者将进行评估 自我报告的集体效率，体育锻炼，饮食和双文化以及客观测量的测量 体育活动，肥胖，感染，胰岛素抵抗和代谢综合征指标。变量 在主要分析中将连续分布。将使用生长曲线估算生长曲线 使用MPLU 3的结构方程框架中的方法论。