Frontiers: University of Kansas Clinical and Translational Science Institute

前沿:堪萨斯大学临床与转化科学研究所

基本信息

  • 批准号:
    9560956
  • 负责人:
  • 金额:
    $ 402.38万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-09-07 至 2022-06-30
  • 项目状态:
    已结题

项目摘要

Contact PD/PI: Barohn, Richard Joel OVERALL: ABSTRACT Frontiers: The Heartland Institute for Clinical and Translational Research has been a catalyst for bringing together translational science investigators and stakeholders across the KC region, and beyond. Located at the University of Kansas Medical Center (KUMC) under the leadership of Dr. Barohn, our commitment to team science and multidisciplinary collaboration reaches beyond the walls of our academic health science center and promotes collaboration among investigators from diverse disciplines across local partner academic institutions and affiliated health care institutions. The vision of Frontiers is to contribute to and lead national efforts to transform the way we do clinical and translational research (CTR), and to ensure research is more rapidly and more efficiently translated to the point of care so that it may contribute to improved health. Specifically, Frontiers aims to: 1) Engage in bi-directional collaboration with all stakeholders to develop, demonstrate, and disseminate advances across the translational science spectrum that insures inclusion and integration of complex and diverse populations and individuals across the lifespan from birth to end of life; 2) Create a sustainable translational workforce of multi-disciplinary investigators, research personnel, and community and patient stakeholders in the use of translational science tools through innovative and creative programs; and 3) Strengthen institutional and regional infrastructure to accelerate translational research. We will accomplish these aims by drawing on our considerable strengths: a) developing informatics tools for making EHR data `research ready' and implementing clinic- and community-based registries for study recruitment and other translational research applications; b) nurturing and sustaining strong patient and community engagement relationships that will support research with African American, Latino, American Indian, LGBTQ, pediatric, geriatric, rare disease, prison, and rural populations; c) offering innovative training programs for the entire CTR workforce (not just investigators), including plans for comprehensive entrepreneurship and implementation research training and creating new team science brainstorming mechanisms that will lead to multidisciplinary discovery projects and d) advancing medical devices and re-purposed drugs to patients through novel strategies developed by Frontiers' Institute for Advancing Medical Innovations (IAMI)that is nationally known for its product development translational research and high impact collaborations with industry, academia, government, and disease philanthropy partners. All Frontiers units are linked by a group of Navigators that can be accessed by Frontiers investigative teams and community partners. These plans position Frontiers to contribute to goals, and lead initiatives of the CTSA network by building on technological, computational, and health/disease knowledge to advance translational research. Project Summary/Abstract Page 274 Contact PD/PI: Barohn, Richard Joel OVERALL NARRATIVE Frontiers: The Heartland Institute for Clinical and Translational Research provides infrastructure and educational programs to develop the next generation of CTR investigative teams. As a regional organization involving two states and three universities, Frontiers is able to blend the best resources available to advance team, community and clinical translational science. This results in accelerating discoveries and research findings that may be more rapidly brought to the point of care and contribute to population health.
联系PD/PI: barhn, Richard Joel

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Richard J. Barohn其他文献

<strong>NEO1 and NEO-EXT studies: Long-term safety and exploratory efficacy of repeat avalglucosidase alfa dosing for 5.5 years in late-onset Pompe disease patients</strong>
  • DOI:
    10.1016/j.ymgme.2019.11.107
  • 发表时间:
    2020-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Mazen M. Dimachkie;Richard J. Barohn;Barry Byrne;Ozlem Goker-Alpan;Priya S. Kishnani;Shafeeq Ladha;Pascal Laforêt;Karl Eugen Mengel;Loren D.M. Pena;Sabrina Sacconi;Volker Straub;Jaya Trivedi;Philip Van Damme;Ans van der Ploeg;John Vissing;Peter Young;Kristina An Haack;Carmen Fleurinck;Judith Johnson;Kejian Liu
  • 通讯作者:
    Kejian Liu
Congenital Myasthenic Syndromes: a Clinical and Treatment Approach
  • DOI:
    10.1007/s11940-018-0520-7
  • 发表时间:
    2018-07-21
  • 期刊:
  • 影响因子:
    1.800
  • 作者:
    Constantine Farmakidis;Mamatha Pasnoor;Richard J. Barohn;Mazen M. Dimachkie
  • 通讯作者:
    Mazen M. Dimachkie
<strong>NEO1/NEO-EXT studies: Safety and exploratory efficacy of repeat avalglucosidase alfa dosing after up to 6 years in participants with late-onset pompe disease (LOPD)</strong>
  • DOI:
    10.1016/j.ymgme.2020.12.064
  • 发表时间:
    2021-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Mazen M. Dimachkie;Richard J. Barohn;Barry Byrne;Ozlem Goker-Alpan;Priya S. Kishnani;Shafeeq Ladha;Pascal Laforêt;Karl Eugen Mengel;Loren D.M. Pena;Sabrina Sacconi;Volker Straub;Jaya Trivedi;Philip Van Damme;Ans van der Ploeg;John Vissing;Peter Young;Kristina An Haack;Inna Ivanina;Xiaoyu Lu; Benedikt Schoser; on behalf of NEO-EXT investigators
  • 通讯作者:
    Benedikt Schoser; on behalf of NEO-EXT investigators
Painful peripheral neuropathy
  • DOI:
    10.1007/s11940-002-0034-0
  • 发表时间:
    2002-05-01
  • 期刊:
  • 影响因子:
    1.800
  • 作者:
    Gil I. Wolfe;Richard J. Barohn
  • 通讯作者:
    Richard J. Barohn

Richard J. Barohn的其他文献

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{{ truncateString('Richard J. Barohn', 18)}}的其他基金

Frontiers: University of Kansas Clinical and Translational Science Institute
前沿:堪萨斯大学临床与转化科学研究所
  • 批准号:
    9514338
  • 财政年份:
    2017
  • 资助金额:
    $ 402.38万
  • 项目类别:
Models of Neuromuscular Disease Across the Lifespan
整个生命周期的神经肌肉疾病模型
  • 批准号:
    9195818
  • 财政年份:
    2016
  • 资助金额:
    $ 402.38万
  • 项目类别:
A Phase II Trial of Rituximab In Myasthenia Gravis
利妥昔单抗治疗重症肌无力的 II 期试验
  • 批准号:
    8644497
  • 财政年份:
    2013
  • 资助金额:
    $ 402.38万
  • 项目类别:
Phase 2B Trial of Memantine for the Treatment of Amyotrophic Lateral Sclerosis
美金刚治疗肌萎缩侧索硬化症的 2B 期试验
  • 批准号:
    8569903
  • 财政年份:
    2013
  • 资助金额:
    $ 402.38万
  • 项目类别:
A Phase II Trial of Rituximab In Myasthenia Gravis
利妥昔单抗治疗重症肌无力的 II 期试验
  • 批准号:
    8731286
  • 财政年份:
    2013
  • 资助金额:
    $ 402.38万
  • 项目类别:
Phase 2B Trial of Memantine for the Treatment of Amyotrophic Lateral Sclerosis
美金刚治疗肌萎缩侧索硬化症的 2B 期试验
  • 批准号:
    8683099
  • 财政年份:
    2013
  • 资助金额:
    $ 402.38万
  • 项目类别:
Phase 2B Trial of Memantine for the Treatment of Amyotrophic Lateral Sclerosis
美金刚治疗肌萎缩侧索硬化症的 2B 期试验
  • 批准号:
    9341908
  • 财政年份:
    2013
  • 资助金额:
    $ 402.38万
  • 项目类别:
Phase 2B Trial of Memantine for the Treatment of Amyotrophic Lateral Sclerosis
美金刚治疗肌萎缩侧索硬化症的 2B 期试验
  • 批准号:
    10242456
  • 财政年份:
    2013
  • 资助金额:
    $ 402.38万
  • 项目类别:
Phase 2 Study of Rasagiline for Treatment of Amyotrophic Lateral Sclerosis
雷沙吉兰治疗肌萎缩侧索硬化症的 2 期研究
  • 批准号:
    8355588
  • 财政年份:
    2012
  • 资助金额:
    $ 402.38万
  • 项目类别:
Phase 2 Study of Rasagiline for Treatment of Amyotrophic Lateral Sclerosis
雷沙吉兰治疗肌萎缩侧索硬化症的 2 期研究
  • 批准号:
    8543461
  • 财政年份:
    2012
  • 资助金额:
    $ 402.38万
  • 项目类别:

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合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
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