IGF::OT::IGF - EPI SUPPORT TO 9 SELF2

IGF::OT::IGF - EPI 支持 9 SELF2

• 批准号: 9369342
• 负责人: CHRISTIE BARKER-CUMMINGS
• 金额: $ 89.44万
• 依托单位: SOCIAL AND SCIENTIFIC SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-26 至 2021-06-25
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9369342
• 关键词: African; Aliquot; Biological Assay; Biological Markers; Blood; Blood specimen; Consent; Contractor; DNA; Data; Development; Fibroid Tumor; Genetic; Genotype; Growth; Hysterectomy; Incidence; Measures; Mutation; Nucleotides; Risk; Risk Factors; Sampling; Serum; Specimen; Swab; Testing; Tissues; Urine; Uterine myomectomy; Vagina; Vitamin D; Vitamin D Deficiency; Woman; follow-up; immune function; mutational status; potential biomarker; sample collection; tumor

The purpose of this task is to examine biological markers of potential risk factors for tumor incidence and growth. The Contractor will analyze the blood, urine, and vaginal swab specimens collected during the 5-year study (final specimen collection to end in 2018) to test two primary hypotheses: 1) the association between Vitamin D deficiency and fibroid development and 2) the association between immune function and fibroids.

这项任务的目的是检查肿瘤发病率和生长的潜在危险因素的生物标志物。承包商将分析5年研究期间采集的血液、尿液和阴道拭子样本（最终样本采集至2018年结束），以检验两个主要假设：1）维生素D缺乏与肌瘤发展之间的关联，以及2）免疫功能与肌瘤之间的关联。