Assessing Spatial Processing Deficits in Cerebral Visual Impairment (CVI) Using Virtual Reality

使用虚拟现实评估脑视觉障碍 (CVI) 的空间处理缺陷

基本信息

  • 批准号:
    9807307
  • 负责人:
  • 金额:
    $ 22.61万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-01 至 2021-06-30
  • 项目状态:
    已结题

项目摘要

Project Summary The objective of the proposed research is to better characterize and understand functional vision processing deficits in cerebral/cortical visual impairment (CVI), the leading cause of congenital vision loss in the United States and developed world. Perinatal damage to developing visual pathways and structures leads to impaired visual spatial processing abilities, particularly in the setting of high environmental complexity and attention demands. Standard clinical assessments and traditional psychophysical stimuli fail to characterize these functional vision deficits due to their lack of ecological validity. To address this unmet need, we have developed a novel virtual reality (VR) based testing platform to assess visual spatial processing abilities in tasks that approach real world situations. In this cross-sectional behavioral study, performance in children and adolescents with CVI will be compared to age-matched ocular visual impaired (OVI) individuals as well as neuro-typical developed sighted controls. Using recorded eye tracking metrics, we will characterize visual search performance and the effect of manipulating stimulus factors in the VR environment. Our central hypothesis is that VR based assessment will reveal impairments in visual spatial processing that are not characterized by standard clinical assessments. In our first aim, we will compare visual spatial processing abilities using two VR based visual search tasks. The first is a static object visual search task (the “virtual toy box”) in which participants must search for a toy positioned in an array of distractor elements (other toys). The second is a dynamic object visual search task (the “virtual corridor”) in which participants must search for the principal of a school in a crowd of distractor elements (other individuals walking in a school corridor). In both tasks, visual search performance will be assessed by varying the number of surrounding distractor elements. We hypothesize that in contrast to individuals with OVI and sighted controls, CVI participants will show greater impairment in performance as a function of increasing visual task demands associated with environmental complexity. In the second aim, we will characterize the effect of manipulating environmental factors using the VR environment on spatial processing abilities. We hypothesize that compared to baseline performance, individuals with CVI will reveal improved performance when target saliency is enhanced, while manipulations that decrease overall target saliency and/or increase task complexity will be associated with impaired performance. The proposed work is of great significance given the potential for developing a novel and ecologically valid VR based platform that provides for superior assessment of visual functional deficits in individuals based on their type of visual impairment. Furthermore, this investigation will help lay the ground work for the creation of new adaptive tools and strategies designed for an individual's specific developmental and rehabilitative needs. This is of particular significance for individuals with CVI; a population that has been greatly underserved despite its important
项目总结

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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Lotfi Merabet其他文献

Lotfi Merabet的其他文献

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{{ truncateString('Lotfi Merabet', 18)}}的其他基金

Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual Impairment
脑视觉障碍中视觉运动处理的神经生理学相关性
  • 批准号:
    10251145
  • 财政年份:
    2020
  • 资助金额:
    $ 22.61万
  • 项目类别:
Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual Impairment
脑视觉障碍中视觉运动处理的神经生理学相关性
  • 批准号:
    10669646
  • 财政年份:
    2020
  • 资助金额:
    $ 22.61万
  • 项目类别:
Characterizing Large-scale Neuroplastic Changes in Cerebral Compared to Ocular Visual Impairment
与眼部视觉障碍相比,大脑中大规模神经塑性变化的特征
  • 批准号:
    10613539
  • 财政年份:
    2020
  • 资助金额:
    $ 22.61万
  • 项目类别:
Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual Impairment
脑视觉障碍中视觉运动处理的神经生理学相关性
  • 批准号:
    10047300
  • 财政年份:
    2020
  • 资助金额:
    $ 22.61万
  • 项目类别:
Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual Impairment
脑视觉障碍中视觉运动处理的神经生理学相关性
  • 批准号:
    10456902
  • 财政年份:
    2020
  • 资助金额:
    $ 22.61万
  • 项目类别:
Characterizing Large-scale Neuroplastic Changes in Cerebral Compared to Ocular Visual Impairment
与眼部视觉障碍相比,大脑中大规模神经塑性变化的特征
  • 批准号:
    10404942
  • 财政年份:
    2020
  • 资助金额:
    $ 22.61万
  • 项目类别:
Assessing Spatial Processing Deficits in Cerebral Visual Impairment (CVI) Using Virtual Reality
使用虚拟现实评估脑视觉障碍 (CVI) 的空间处理缺陷
  • 批准号:
    10005388
  • 财政年份:
    2019
  • 资助金额:
    $ 22.61万
  • 项目类别:
Audio Based Navigation in the Blind
基于音频的盲人导航
  • 批准号:
    8018059
  • 财政年份:
    2010
  • 资助金额:
    $ 22.61万
  • 项目类别:
Audio Based Navigation in the Blind
基于音频的盲人导航
  • 批准号:
    8417709
  • 财政年份:
    2010
  • 资助金额:
    $ 22.61万
  • 项目类别:
Audio Based Navigation in the Blind
基于音频的盲人导航
  • 批准号:
    8212081
  • 财政年份:
    2010
  • 资助金额:
    $ 22.61万
  • 项目类别:

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