Implementation of Chlorhexidine Bathing to Reduce Healthcare-Associated Infections-the Icare study

实施洗必太沐浴以减少医疗相关感染 - Icare 研究

• 批准号: 9301469
• 负责人: NASIA SAFDAR
• 金额: $ 48.79万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-10 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9301469
• 关键词: Implementation; Chlorhexidine; Bathing; Reduce; Healthcare

 DESCRIPTION (provided by applicant): Healthcare-associated infections cause increased morbidity, mortality and medical costs. It is estimated that 722,000 people get a healthcare-associated infection every year (1 in 25 hospitalized patients) and 75,000 people with HAIs die. In recent years, the evidence base for interventions to reduce healthcare-associated infections has grown substantially and HAIs are considered largely preventable and a patient safety issue. However, a considerable gap continues to exist between evidence and practice in the field of healthcare-associated infection prevention. Thus, an important opportunity and challenge to reduce the health and economic burden of healthcare-associated infection in the United States is the translation of interventions in multiple real world settings. Daily chlorhexidine bathing isan efficacious and effective intervention that can reduce healthcare-associated infections. Key issues to address to disseminate this intervention into widespread practice include the adaptation of the intervention for use in multiple settings and populations; research on the feasibility, acceptability, reach and uptake of the intervention for both the facility and individul participants and implementation evaluation including barriers and facilitators assessment. We propose to implement and evaluate the process of implementing a daily chlorhexidine bathing intervention using an innovative systems engineering approach, the Systems Engineering Initiative for Patient Safety in multiple non ICU settings. We will employ a mentored implementation approach and will evaluate the implementation using a multiple case study approach including assessment of barriers and facilitators and fidelity to the daily chlorhexidine bathing intervention using direct observations, chlorhexidine usage, electronic health record documentation and microbiologic assessment of chlorhexidine concentrations. We will also explore the impact of the daily chlorhexidine bathing intervention on healthcare-associated infections. This study will provide a framework to implement and evaluate other evidence-based interventions for healthcare- associated infection prevention.



项目成果

Every other day bathing with chlorhexidine gluconate: what is the evidence?

每隔一天用葡萄糖酸氯己定洗澡：证据是什么？

• DOI: 10.21037/atm.2016.11.83
• 发表时间: 2016
• 期刊: Annals of translational medicine
• 作者: Musuuza,JacksonS;Safdar,Nasia
• 通讯作者: Safdar,Nasia

Assessing the sustainability of daily chlorhexidine bathing in the intensive care unit of a Veteran's Hospital by examining nurses' perspectives and experiences.

• DOI: 10.1186/s12879-017-2180-8
• 发表时间: 2017-01-14
• 期刊: BMC infectious diseases
• 影响因子: 3.7
• 作者: Musuuza JS;Roberts TJ;Carayon P;Safdar N
• 通讯作者: Safdar N

Crossing the quality chasm for Clostridium difficile infection prevention.

跨越艰难梭菌感染预防的质量鸿沟。

• DOI: 10.1136/bmjqs-2015-004344
• 发表时间: 2015
• 期刊: BMJ quality & safety
• 影响因子: 5.4
• 作者: Safdar,Nasia;Perencevich,Eli
• 通讯作者: Perencevich,Eli

Teaching health care workers to adopt a systems perspective for improved control and prevention of health care-associated infections.

教导卫生保健工作者采用系统视角来改善卫生保健相关感染的控制和预防。

• DOI: 10.1016/j.ajic.2016.04.211
• 发表时间: 2016
• 期刊: American journal of infection control
• 影响因子: 4.9
• 作者: Ruis,AR;Shaffer,DavidWilliamson;Shirley,DanielK;Safdar,Nasia
• 通讯作者: Safdar,Nasia