The effect of chlorhexidine to improve dentin bond durability

我研究了氯己定掺入实验牙本质粘合剂与不同的结晶度的氯己定释放和微拉伸粘结强度的牙本质标本制备后24小时和14个月后的效果。释放的氯己定越多，亲水性树脂共聚单体越多。在所有粘合剂组中观察到粘合强度显著降低，但含氯己定的最疏水粘合剂除外。此外，MMA为基础的树脂被用来衡量洗必泰从树脂水泥通过HPLC释放，并对变形链球菌和粪肠球菌的抗菌效果。 3.0和4.0%氯己定骨水泥显示氯己定释放5周;然而，超过98%的氯己定保留在树脂基质中。含3.0和4.0%洗必泰的树脂骨水泥具有2周的洗必泰缓释和抗菌性能。

I studied the effect of chlorhexidine incorporation into experimental dentin adhesives with different hydrophilicities on the chlorhexidine release and the microtensile bond strength to dentin after 24 h and 14 months after specimen preparation. The more chlorhexidine released the more hydrophilic resin co-monomers. Significant reduction in bond strength was observed in all adhesive groups, except for chlorhexidine-containing most hydrophobic adhesive. Also, MMA-based resin was used to measure chlorhexidine-release from resin cement by means of HPLC, and antibacterial effect against Streptococcus mutans and Enterococcus faecalis. The 3.0 and 4.0% chlorhexidine-incorporated cement exhibited chlorhexidine release for 5 weeks; however, more than 98% of chlorhexidine was retained in resin matrix. The 3.0 and 4.0% chlorhexidine-incorporated resin cement possessed prolonged chlorhexidine release and antibacterial properties for 2 weeks.