Georgia CTSA Research Supplement to Promote Diversity in Health-Related Research (Hernandez)

佐治亚州 CTSA 研究增刊促进健康相关研究的多样性 (Hernandez)

• 批准号: 9815750
• 负责人: HENRY M BLUMBERG
• 金额: $ 3.46万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-24 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9815750
• 关键词: Address; Affect; Behavior; Clinical; Clinical Research; Clinical Sciences; Communities; Community Health Aides; Doctor of Philosophy; Ethnic group; Growth; Health; Hispanics; Immigrant; Intervention; Knowledge; Latina; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentorship; Methods; Mexican; Minority; Modeling; Prevention Research; Preventive; Principal Investigator; Research; Research Proposals; Role; Rural; Stress; System; Training; Translational Research; Vulnerable Populations; Woman; Work; anticancer research; base; cancer diagnosis; cancer health disparity; cancer prevention; career; cervical cancer prevention; contextual factors; experience; improved; innovation; outreach; parent grant; programs; public health relevance; racial and ethnic; rural area; rural underserved; trend

Program Director/Principal Investigator (Last, First, Middle): Taylor, W. Robert Project Summary/Abstract This diversity supplement builds upon the work of the Georgia Clinical and Translational Science Alliance (Georgia CTSA) (ULTR002378) parent grant by conducting translational research and better engaging rural and underserved Georgia Latinas in cervical cancer prevention, and participation in cancer clinical research. Latina women are disproportionately impacted by cervical cancer in comparison to women from other racial/ethnic groups. In the state of Georgia, this national trend remains as Latinas are disproportionately affected by higher rates of cervical cancer diagnoses compared to non-Latina black and white women. Although studies have identified facilitators to cervical cancer prevention among Latinas, they are narrow in scope and don't address Latinas residing in rural areas and the boarder contextual factors that may prohibit women from participating in prevention and clinical research. Using community engaged approaches applied through a minority stress framework, the objective of this research proposal is to identify and improve our understanding of the facilitators and barriers to cervical cancer prevention, and participation in cancer clinical research among rural Mexican immigrant Latinas in Georgia. Using a mixed-methods approach, the specific aims include: Aim 1a: To identify the facilitators and barriers of cervical cancer prevention methods among rural Latina women in Georgia; Aim1b: To investigate the role of promotoras (community health workers) and other community-based, cancer prevention opportunities and outreach strategies to decrease cervical cancer disparities; and Aim 2: To assess factors associated with Latina participation in clinical cervical cancer research. Hypothesis: Immigrant related minority stress factors will significantly decrease the likelihood of preventive behaviors, and participation in clinical research among rural Latina immigrants. This study is significant because Latina women simultaneously experience the greatest burden of cervical cancer health disparities and are the fastest growing major demographic in the U.S, thus this growth may exacerbate the burden of cervical cancer. The research is innovative because it: (1) focuses on a largely rural, underserved, vulnerable population with unique and specific needs; (2) uses the Minority Stress Model that has not being applied in cancer research; and (3) engages the community as a part of the interdisciplinary team. Research findings will be used to inform to inform community and system-level approaches to address a persistent disparity. OMB No. 0925-0001/0002 (Rev. 01/18 Approved Through 03/31/2020) Page Continuation Format Page

项目主任/主要研究者（最后，第一，中间）：泰勒，W。罗伯特 项目总结/摘要 这种多样性补充建立在格鲁吉亚临床和转化科学的工作 联盟（格鲁吉亚CTSA）（ULTR 002378）通过进行转化研究和更好的父母补助金 让农村和得不到充分服务的格鲁吉亚拉丁人参与宫颈癌预防， 癌症临床研究。拉丁妇女受宫颈癌的影响不成比例， 与其他种族/族裔群体的妇女相比。在格鲁吉亚州，这种全国性的趋势 仍然是拉丁美洲人不成比例地受到宫颈癌诊断率较高的影响， 与非拉丁裔黑人和白色女性相比。虽然研究已经确定了促进者， 宫颈癌的预防拉丁美洲人，他们是范围狭窄，不解决拉丁美洲人 居住在农村地区以及可能妨碍妇女参与的边界环境因素 预防和临床研究。通过少数群体采用社区参与的方法 强调框架，这项研究建议的目的是确定和提高我们的理解 预防宫颈癌的促进因素和障碍，以及参与癌症临床 在格鲁吉亚的墨西哥移民拉丁美洲农村的研究。使用混合方法， 具体目标包括：目标1a：确定预防宫颈癌的促进因素和障碍 方法在农村拉丁妇女在格鲁吉亚;目的1b：调查的作用promotoras （社区卫生工作者）和其他以社区为基础的癌症预防机会， 减少宫颈癌差异的外展战略;以及目标2：评估与宫颈癌相关的因素， 与拉丁裔参与临床宫颈癌研究。假设：与移民有关的少数群体 压力因素会显著降低预防行为的可能性， 拉丁裔农村移民的临床研究这项研究意义重大，因为拉丁妇女 同时经历宫颈癌健康差距的最大负担， 美国增长最快的主要人口，因此这种增长可能会加剧 宫颈癌这项研究是创新的，因为它：（1）侧重于一个主要是农村，服务不足， 具有独特和具体需求的弱势群体;（2）使用少数民族压力模型， （3）将社区作为跨学科的一部分， 团队研究结果将用于为社区和系统一级的办法提供信息， 解决持续存在的差距。 OMB编号0925-0001/0002（2018年1月批准至2020年3月31日修订版）页码续页格式页码