Tufts Clinical and Translational Science Institute

塔夫茨临床与转化科学研究所

• 批准号: 9816143
• 负责人: Harry P. Selker
• 金额: $ 13.45万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-05 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9816143
• 关键词: Acculturation; Active Learning; Address; African American; Appalachian Region; Behavior; Biometry; Center for Translational Science Activities; Chinese American; Clinical; Clinical Research; Clinical Sciences; Communities; Data Analyses; Discipline; Discrimination; Environment; Evaluation; Goals; Institutes; Intervention; Latina; Latino; Location; Longevity; Mentors; Mentorship; Methods; Multi-Institutional Clinical Trial; Participant; Performance; Population Heterogeneity; Process; Puerto Rico; Research; Research Design; Research Personnel; Research Training; Resource Sharing; Resources; Risk Behaviors; Risk Factors; Role; Science; Screening for cancer; Services; Training; Training Support; Training and Education; Translational Research; Translations; Work; cancer prevention; cancer risk; career; community based participatory research; epidemiology study; ethnic diversity; health disparity; innovation; investigator training; novel; programs; racial and ethnic; racial diversity; skills

Project Abstract Maria Rodriguez Berrios ND is a promising early investigator with a focus on translational research addressing health disparities and community based participatory research. As a Latina investigator from Puerto Rico, she is committed to research that is broadly stakeholder engaged to eliminate health disparities. This diversity supplement will provide her the training and support through Tufts CTSI to reach her training goals. The training goals of the proposed investigator are well aligned with the overall aims and the community engagement and the research resources aims of Tufts CTSI: Overall AIM 1: Create an environment, resources, and services to stimulate and support the full spectrum of clinical and translational research (CTR) by leveraging the diverse expertise and assets of Tufts CTSI partners. Overall AIM 2: Cultivate broadly-engaged team science, actively including stakeholders, to promote relevant and impactful translation for diverse populations and across the lifespan. Overall AIM 3: Develop, demonstrate, and disseminate innovations in methods, research process improvement, and evaluation, to advance CTR locally and nationally. Overall AIM 4: Advance methods and performance of multi-site clinical trials, within the Tufts CTSI Clinical Research Network (CRN), the NCATS Trial Innovation Network, and in other multi-institutional networks. Overall AIM 5: Provide outstanding education, training, and mentoring, tailored to different roles and disciplines, to advance a diverse CTR workforce, and share these resources nationally. The candidate will utilize the resources of Tufts CTSI beginning with the training available through the Clinical and Translational Sciences graduate program. Using the skills she gains in the graduate program, she will conduct a data analysis to understand the impact of multiple risk factors, including novel risk factors of acculturation and discrimination on cancer screening and cancer prevention behaviors. This work, including community participants from African American, Chinese American, Latino, and Appalachian communities, will provide a broad perspective on the impact of location and racial/ethnic diversity and these novel risk factors on cancer prevention behaviors, and will provide targets for potential novel interventions to address cancer risk behaviors. Dr. Rodriguez Berrios will benefit from the resources of Tufts CTSI to achieve her research training aims, and prepare her for an independent research career. She will engage with the Stakeholder and Community Engagement Resource, the Clinical Translational Research Center, and the Biostatistics, Epidemiology and Research Design resources for experiential learning, and couple this with the formal training in the Clinical Translational Science Graduate Program and the mentorship of the Tufts CTSI PI and KL2 PI in order to develop the skills in broadly engaged team science.

项目摘要 玛丽亚·罗德里格斯·贝里奥斯ND是一个有前途的早期研究者，专注于翻译研究， 健康差距和社区参与性研究。作为一名来自波多黎各的拉丁裔调查员，她 致力于广泛参与利益相关者的研究，以消除健康差距。这种多样性 补充将通过塔夫茨CTSI为她提供培训和支持，以实现她的培训目标。 拟议调查员的培训目标与总体目标和社区保持一致 参与和塔夫茨CTSI的研究资源目标： 总体目标1：创造环境、资源和服务，以激励和支持全方位的 通过利用塔夫茨CTSI合作伙伴的各种专业知识和资产，开展临床和转化研究（CTR）。 总体目标2：培养广泛参与的团队科学，积极包括利益相关者，以促进相关的 以及对不同人群和整个生命周期有影响力的翻译。 总体目标3：开发、展示和传播方法、研究过程中的创新 改进和评价，以促进地方和国家的合作减少灾害风险。 总体目标4：Tufts CTSI临床试验中多中心临床试验的先进方法和性能 研究网络（CRN），NCATS试验创新网络，以及其他多机构网络。 总体目标5：提供针对不同角色的出色教育、培训和指导， 学科，推进多元化的CTR劳动力，并在全国范围内共享这些资源。 候选人将利用塔夫茨CTSI的资源，从临床培训开始， 翻译科学研究生课程。利用她在研究生课程中获得的技能，她将 进行数据分析，以了解多种风险因素的影响，包括新的风险因素 文化适应和歧视对癌症筛查和癌症预防行为的影响。这项工作，包括 来自非裔美国人、华裔美国人、拉丁美洲人和阿巴拉契亚社区的社区参与者将 提供了一个广泛的视角，对地点和种族/民族多样性的影响，以及这些新的风险因素， 癌症预防行为，并将为潜在的新干预措施提供目标，以解决癌症风险 行为。Rodriguez Berrios博士将受益于塔夫茨CTSI的资源，以实现她的研究培训 目标，并为她的独立研究生涯做准备。她将与利益相关者接触， 社区参与资源，临床转化研究中心和生物统计学， 流行病学和研究设计体验式学习的资源，并将其与正式培训相结合 临床转化科学研究生课程和塔夫茨CTSI PI和KL 2 PI的指导， 以发展广泛参与团队科学的技能。