Tufts Clinical and Translational Science Institute

塔夫茨临床与转化科学研究所

• 批准号: 10622002
• 负责人: Harry P. Selker
• 金额: $ 1139.42万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2030-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10622002
• 关键词: Abbreviations; Address; Advisory Committees; Asian population; Belief; Biometry; Caring; Center for Translational Science Activities; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Data Monitoring Committees; Collaborations; Communication; Communities; Data; Data Science; Development; Discipline; Disparity; Dissemination and Implementation; Education; Electronic Health Record; Elements; Environment; Epidemiology; Equity; Evaluation; Fast Healthcare Interoperability Resources; Fostering; Good Clinical Practice; Growth; Health; Health Alliance; Health Policy; Health system; Informatics; Investigation; Leadership; Learning; Medical; Medical center; Mentors; Mentorship; Methods; Nature; Operations Research; Outcome; Population Heterogeneity; Process; Public Health; Research; Research Design; Research Ethics; Research Methodology; Resource Sharing; Resources; Role; Science; Services; System; Technology; Training; Training and Education; Translational Research; Translations; Trust; Universities; Vision; Work; care delivery; clinical center; clinical practice; clinical predictive model; cohort; coronavirus disease; data modeling; data warehouse; health data; health equity; health equity promotion; improved; innovation; insight; interoperability; language processing; medical schools; novel; patient oriented; pre-clinical; programs; recruit; skills; translational pipeline

TUFTS CTSI OVERALL PROJECT SUMMARY Over its 14 years, Tufts Clinical and Translational Science Institute (CTSI) has brought together partners and collaborators and has grown programs and activities to catalyze clinical and translational research (CTR) and to advance innovation in clinical and translational science (CTS). We focus on what we are best suited to do, based on our skills, resources, partners, and opportunities. Thereby, we provide outstanding services, resources, education, and mentorship, and conduct innovative research contributing to the field of CTS, locally and nationally. With this application, retaining our important structural features of integration across all of Tufts University, of having purposefully-selected partners, and adhering to our foundational principles, we are pleased to further grow our offerings and ambitions leveraging our long-standing partners’ contributions and assets and by adding the special assets of new partners. With growth, our foundational principles have not changed. We actively support the full spectrum of translational research, we practice “broadly-engaged team science,” and we are active collaborators, embracing our role as “the extrovert CTSA.” We believe that only by having systems and processes to continually assess and improve methods and operational principles will we achieve CTR/CTS excellence. We practice inclusive communications and work to advance health equity. And we insist that wherever work is on the T.5-T4 continuum, CTR must have a clear line of sight to potential ultimate impact on health. In addition to these foundational principles, in all we do, we reflexively look for opportunities to contribute novel research methods. Development, demonstration, and dissemination of new methods and approaches are hallmarks of our work, regardless of domain. Also, we manifest our belief that rigorous role-specific inclusive education and training are fundamental to excellence and advancing CTR/CTS. In service of these principles, our aims are: Overall AIM 1: Harness the collective impact of Tufts CTSI to advance CTS and improve public health through responsive Hub leadership, an inclusive and collaborative culture, and continuous improvement of programs and research. Overall AIM 2: Provide outstanding education, training, and mentoring, tailored to different roles and disciplines, to develop an expert and diverse CTS workforce, and share these resources nationally. Overall AIM 3: Cultivate broadly-engaged team science, with active inclusion of all stakeholders, to promote relevant and impactful translation for diverse populations and to promote health equity. Overall AIM 4: Create the environment, resources, and services to stimulate and support the full spectrum of CTS by leveraging the diverse expertise and assets of Tufts CTSI partners. Overall AIM 5: Foster translation by developing, demonstrating, and disseminating innovations that address significant translational roadblocks and provide generalizable translational insights and solutions.

TUFTS CTSI 总体项目摘要 14 年来，塔夫茨临床与转化科学研究所 (CTSI) 汇聚了合作伙伴 和合作者，并制定了促进临床和转化研究 (CTR) 的计划和活动 并推动临床和转化科学（CTS）的创新。我们专注于我们最适合的事情 根据我们的技能、资源、合作伙伴和机会去做。因此，我们提供卓越的服务， 资源、教育和指导，并开展为当地 CTS 领域做出贡献的创新研究 和全国范围内。通过此应用程序，保留了我们在所有塔夫茨大学中集成的重要结构特征 大学，拥有精心挑选的合作伙伴，并坚持我们的基本原则，我们是 很高兴利用我们长期合作伙伴的贡献和 资产并通过添加新合作伙伴的特殊资产。 随着增长，我们的基本原则没有改变。我们积极支持全方位 转化研究，我们实践“广泛参与的团队科学”，我们是积极的合作者， 接受我们作为“外向 CTSA”的角色。我们相信，只有通过系统和流程 不断评估和改进方法和运营原则，我们才能实现卓越的 CTR/CTS。我们 实行包容性沟通并努力促进健康公平。我们坚持认为无论工作在哪里 在 T.5-T4 连续体中，CTR 必须对健康的潜在最终影响有清晰的认识。此外 这些基本原则，在我们所做的一切中，我们本能地寻找贡献新颖研究的机会 方法。新方法和途径的开发、示范和传播是 我们的工作，无论领域如何。此外，我们表达了我们的信念：严格的针对特定角色的包容性教育和 培训是卓越和提高 CTR/CTS 的基础。 为了服务于这些原则，我们的目标是： 总体目标 1：利用塔夫茨 CTSI 的集体影响力 通过积极响应的中心领导力、包容性和协作性，推进 CTS 并改善公共卫生 文化，以及项目和研究的持续改进。总体目标 2：提供卓越的 针对不同角色和学科量身定制的教育、培训和指导，培养专家和多元化的人才 CTS 员工队伍，并在全国范围内共享这些资源。总体目标 3：培养广泛参与的团队 科学，所有利益相关者的积极参与，促进不同领域的相关和有影响力的翻译 人口并促进健康公平。总体目标 4：创造环境、资源和服务 利用塔夫茨 CTSI 的多元化专业知识和资产，刺激和支持全方位的 CTS 合作伙伴。总体目标 5：通过开发、展示和传播创新来促进翻译 解决重大的转化障碍并提供通用的转化见解和解决方案。