Tufts Clinical and Translational Science Institute

在过去的10年里，塔夫茨临床和转化科学研究所（CTSI）汇集了 有目的地选择合作伙伴，并组织了新的和现有的计划和活动， 目的是为临床和转化研究（CTR）做出最大贡献。我们专注于我们最适合的事情 根据我们的特殊技能、资源、合作伙伴和机会来做。因此，我们能够 提供独特和优秀的服务，资源，教育和指导，地方，全国，并向 CTR领域有了这个应用程序，我们很高兴能够通过扩展 我们的长期合作伙伴的贡献，并通过增加新的合作伙伴的特殊资产。 随着公司的发展，我们的指导原则没有改变：1）我们积极支持全方位的翻译服务， 研究，我们坚持认为，无论在T1-T4连续体，CTR必须有一个清晰的视线，以潜力 对健康的最终影响; 2）在研究的各个阶段，我们都在实践“广泛参与的团队科学”。对于CTR 为了具有相关性和影响力，研究团队必须从一开始就拥有广泛的利益相关者， （3）我们是积极的合作者。我们接受我们作为“外向的CTSA”的角色。 我们相信，不同学科、利益相关者和组织之间的联系是协同的， 很多层次。这为我们的中心提供了动力，并为我们在多个CTSA联盟活动中的领导地位提供了动力; 4）我们 我认为，只有通过系统和过程来持续评估和迭代改进过程， 我们将实现卓越的CTR。我们有一个研究过程改进的签名程序，我们 适用于整个CTR，这导致我们领导了CTSA共同战略的全国推广; 5）我们 条件反射地寻找机会贡献新的研究方法。开发、演示和 传播新的方法和途径是我们工作的标志，无论领域如何; 6）严格 针对特定角色的教育和培训是实现卓越合作伙伴关系和推进合作伙伴关系的基础。 为了服务于这些原则，我们的目标是：1）创造一个环境，资源和服务， 通过利用塔夫茨CTSI的各种专业知识和资产，促进和支持CTR的全方位发展 伙伴2）培养广泛参与的科学团队，积极包括利益相关者，以促进 为不同人群和整个生命周期提供相关和有影响力的翻译。总体目标3）发展， 展示和传播方法创新、研究过程改进和评估， 在当地和全国范围内推进CTR。总体目标4）多中心临床的先进方法和性能 试验，在塔夫茨CTSI临床研究网络，NCATS试验创新网络，并在其他 多机构网络。总体目标5）提供出色的教育、培训和指导， 不同的角色和学科，以推进多元化的CTR劳动力，并在全国范围内共享这些资源。

Over its 10 years, Tufts Clinical and Translational Science Institute (CTSI) has brought together purposefully-selected partners and has organized new and existing programs and activities with a singular purpose to best contribute to clinical and translational research (CTR). We focus on what we are best suited to do, based on our particular skills, resources, partners, and opportunities. Thereby, we have been able to provide unique and outstanding services, resources, education, and mentorship, locally, nationally, and to the field of CTR. With this application, we are pleased to be able to substantially grow our offerings by expanding our long-standing partners’ contributions, and by adding the special assets of new partners. With growth, our guiding principles have not changed: 1) We actively support the full spectrum of translational research, and we insist that wherever on the T1-T4 continuum, CTR must have a clear line of sight to potential ultimate impact on health; 2) At all stages of research, we practice “broadly-engaged team science.” For CTR to be relevant and impactful, research teams must have a wide array of stakeholders from inception to completion and dissemination; 3) We are active collaborators. We embrace our role as “the extrovert CTSA.” We believe that connections among diverse disciplines, stakeholders, and organizations are synergistic on many levels. This has powered our hub, and our leadership of multiple CTSA Consortium activities; 4) We believe that only by having systems and processes to continually assess and to iteratively improve processes will we achieve CTR excellence. We have a signature program in research process improvement, which we apply across CTR, and which led to our leading the national roll-out of the CTSA Common Metrics; 5) We reflexively look for opportunities to contribute novel research methods. Development, demonstration, and dissemination of new methods and approaches are hallmarks of our work, regardless of domain; 6) Rigorous role-specific education and training are fundamental to excellence in, and advancing, CTR. In service of these principles, our aims are: Overall AIM 1) Create an environment, resources, and services to stimulate and support the full spectrum of CTR by leveraging the diverse expertise and assets of Tufts CTSI partners. Overall AIM 2) Cultivate broadly-engaged team science, actively including stakeholders, to promote relevant and impactful translation for diverse populations and across the lifespan. Overall AIM 3) Develop, demonstrate, and disseminate innovations in methods, research process improvement, and evaluation, to advance CTR locally and nationally. Overall AIM 4) Advance methods and performance of multi-site clinical trials, within the Tufts CTSI Clinical Research Network, the NCATS Trial Innovation Network, and in other multi-institutional networks. Overall AIM 5) Provide outstanding education, training, and mentoring, tailored to different roles and disciplines, to advance a diverse CTR workforce, and share these resources nationally.