Oregon Clinical and Translational Research Institute TL1 Program

俄勒冈临床和转化研究所 TL1 项目

• 批准号: 9514380
• 负责人: ALLISON Deborah FRYER
• 金额: $ 52.04万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-02 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9514380
• 关键词: Academy; Award; Basic Science; Biomedical Research; Clinic; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communication; Competence; Consensus; Critical Thinking; Critiques; Degree requirements; Dental Schools; Discipline; District of Columbia; Doctor of Philosophy; Educational Curriculum; Enrollment; Environment; Equipment and supply inventories; Evaluation Studies; Exercise; Extramural Activities; Fellowship; Grant; Individual; Institute of Medicine (U.S.); Internet; Journals; Leadership; Learning; Mentors; Methods; Modeling; National Cancer Institute; National Research Service Awards; Nature; Oregon; Phase; Physicians; Problem Solving; PubMed; Publishing; Qualifying; Readiness; Recruitment Activity; Reporting; Research; Research Institute; Research Proposals; Research Training; Resources; Sample Size; Science; Scientist; Students; System; TNFSF15 gene; Time Management; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; University resources; Validation; Wisconsin; Writing; behavioral/social science; career; career development; clinical development; data management; design; education research; experience; graduate student; instrument; medical schools; peer; programs; research clinical testing; skills; success; translational scientist; working group

Contact PD/PI: Ellison, David H. NRSA-Training-001 (822) The Oregon Students Learn and Experience Research (OSLER) TL1 program is created to train transdisciplinary clinical and translational researchers. To maximize a transdisciplinary environment, we will provide training in clinical and translational science to graduate PhD students (basic science, behavioral, social science) as well as MD and DMD students. We will build upon our successful TL1 program by recruiting PhD students from OHSU basic science programs, as well as from Portland State University, University of Oregon, and Oregon State University. Graduate students will participate after satisfactorily completing their qualifying exam; MD and DMD students will most likely participate between their third and fourth year of medical or dental school. Graduate and professional students will design an individual plan for this fellowship that is specific to career plans as well as to their proposed research. MD and DMD students will enroll in the Master of Clinical Research (MCR) program and will complete all requirements for the degree within the training period. This didactic program is specifically constructed around the “case” of the trainee's mentored research; as trainees progress in the curriculum, they develop research skills through class exercises such as writing a research proposal and IRB form, designing the data management system, and calculating power and sample size. Graduate students will be encouraged to participate in the MCR, but at a minimum must complete competencies in quantitative methods, data management, and research leadership. All students will participate in the FOLIO curriculum, which is designed to provide practical skills of critical thinking, time management, team science, design science, and problem solving. TL1 trainees will also be trained in science communication and writing. Two key experiences will enhance the transdisciplinary training: a clinical and translational science journal club, and participation in the MD/PhD grant rounds. Through participating in common activities, students from different disciplines will gain an understanding of the benefits of team science and will enhance their ability to understand the clinical setting of their research. PhD students will be provided with enhancement experiences such as attending clinics and rounds with clinicians in their research focus. This program will create clinicians and scientists who will pursue careers in transdisciplinary clinical and translational science. Project Summary/Abstract Page 1288 Contact PD/PI: Ellison, David H. NRSA-Training-001 (822) References 1. The Physician-Scientist Workforce Working Group. The Physician-Scientist Workforce Working Group, National Institutes of Health; 2014. 2. Alberts B, Kirschner MW, Tilghman S, Varmus H. Rescuing US biomedical research from its systemic flaws. PNAS. 2014; 111(16): 5773-5777. doi: 10.1073/pnas.1404402111. PubMed PMID: 24733905; PMCID: PMC4000813. 3. Tilghman S, Rockey S, Degen S, Forese L, Ginther D, Gutierrez-Hartmann A. Biomedical research workforce working group report. Bethesda, MD: National Institutes of Health. 2012. 4. IOM (Institute of Medicine). The CTSA program at NIH: Opportunities for advancing clinical and translational research. Washington DC: The National Academies Press, 2013. 5. Resources for each phase of the mentoring relationship [homepage on the Internet]. Mentoring Resources: University of Wisconsin Madison [cited 2015]. Available from: https ://m entoringres ourc es .ic tr.wis c .edu/MentoringRes ourc es . 6. Fleming M, House S, Hanson VS, Yu L, Garbutt J, McGee R, Kroenke K, Abedin Z, Rubio DM. The mentoring competency assessment: Validation of a new instrument to evaluate skills of research mentors. Acad Med. 2013; 88(7): 1002-1008. doi: 10.1097/ACM.0b013e318295e298. PubMed PMID: 23702534; PMCID: PMC3727250. 7. Rubio DM, Primack BA, Switzer GE, Bryce C, Seltzer DL, Kapoor, WN. A comprehensive career- success model for physician-scientists. Acad Med. 2011; 86(12). 1571-1576. doi: 10.1097/ACM.0b013e31823592fd. PubMed PMID: 22030759; PMCID: PMC3228877. 8. Keller TE, Collier PJ, Blakeslee JE, Logan K, McCracken K, Morris C. Early career mentoring for translational researchers: Mentee perspectives on challenges and issues. Teach Learn Med. 2014; 26(3): 211- 216. doi: 10.1080/10401334.2014.883983. PubMed PMID: 25010230; PMCID: PMC4114132. 9. Lipira L, Jeffe DB, Krauss M, Garbutt J, Piccirillo J, Evanoff B, Fraser V. Evaluation of clinical research training programs using the clinical research appraisal inventory. Clin Transl Sci. 2010; 3(5): 243-248. doi: 10.1111/j.1752-8062.2010.00229.x. PubMed PMID: 21442017; PMCID: PMC3062999. 10. Meyers FJ, Begg M, Fleming M, Merchant C. Strengthening the career development of clinical and translational scientist trainees: A consensus statement of the Clinical and Translational Science Award (CTSA) Research Education and Career Development Committees. Clin Trans Sci. 2012; 5(2): 132-7. doi: 10.1111/j.1752-8062.2011.00392.x. PubMed PMID: 22507118; PMCID: PMC3771692. 11. Allen L, Scott J, Brand A, Hlava M, Altman M. Publishing: Credit where credit is due. Nature. 2014; 508(7496): 312-313. doi: 10.1038/508312a. PubMed PMID: 24745070. 12. Core competencies in clinical and translational research [homepage on the Internet]. The Clinical and Translational Science Awards (CTSA) Consortium. July 14, 2009 [cited 2015]. Available from: https://ctsacentral.org/wp-content/docum ents/CTSA%20Core%20Com petencies_%20final%202011.pdf . 13. Hall KL, Stokols D, Moser RP, Taylor BK, Thornquist MD, Nebeling LC, Ehret CC, Barnett MJ, McTiernan A, Berger NA, Goran MI, Jeffery RW. The collaboration readiness of transdisciplinary research teams and centers: Findings from the National Cancer Institute's TREC Year-One evaluation study. Am J Prev Med. 2008; 35(2S): S161-S172. doi: 10.1016/j.amepre.2008.03.035. PubMed PMID: 18619396; PMCID: PMC3292855. 14. Definitions of criteria and considerations for K critiques [homepage on the Internet]. National Institutes of Health (NIH), Office of Extramural Research. July 16, 2015 [cited 2015]. Available from: http://grants .nih.gov/grants /peer/c ritiques /k.htm . References Cited Page 1289

联系PD/PI: Ellison， David H. NRSA-Training-001 （822）