Kentucky Center for Clinical and Translational Science

肯塔基州临床和转化科学中心

基本信息

批准号：
9314011
负责人：
Philip A Kern
金额：
$ 364.53万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-08-15 至 2020-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9314011
关键词：
Abbreviations Academic Medical Centers Affect Agriculture Appalachian Region Arts Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Network Collaborations Communities Data Development Discipline Diverse Workforce Education Engineering Environment Fostering Future Goals Health Healthcare Healthcare Systems Home environment Informatics Institutes Institution Interdisciplinary Study Kentucky Lead Leadership Longevity Marshal Medical center Methodology Mission Multi-Institutional Clinical Trial Participant Personal Satisfaction Phase Population Positioning Attribute Quality of life Research Research Training Role Rural Rural Community Rural Population Scholarship Science Solid Target Populations Translational Research Trust Universities West Virginia Work Workforce Development abstracting base biomedical informatics catalyst collaborative environment college data management drug development food environment health care quality health care service organization health disparity healthcare community improved innovation medical schools medically underserved meetings named group novel novel therapeutics programs success

项目摘要

Contact PD/PI: Kern, Philip A PROJECT SUMMARY The University of Kentucky (UK) Center for Clinical and Translational Science (CCTS) has created an integrated home for clinical and translational research to promote scientific progress and discoveries at every phase of the translational continuum. The CCTS has fundamentally transformed the research environment not only at UK but throughout Central Appalachia through the development of a strong research network, the Appalachian Translational Research Network (ATRN), with integrated research partnerships including other CTSA hubs. When combined with an in-depth understanding of the unique and serious health challenges faced by Central Appalachian residents, the UK CCTS is positioned to lead local, regional and national research efforts that focus on the significant health disparities in this population. Our overarching goal as a CTSA hub is to continue to champion innovation in the full spectrum of clinical and translational research while educating the workforce of the future, engaging our communities in biomedical science and working with the national network to advance cohesive multi-center clinical trials, which will ultimately elevate the health and quality of life of the populace of Central Appalachia. Specifically, the UK CCTS will: 1) Lead institutional innovation in the delivery of efficient, effective clinical and translational research. 2) Develop a diverse workforce across multiple disciplines that advances translational research and excels in team-based science. 3) Meet the unique needs of Central Appalachian residents by extensively engaging and collaborating with our regional, rural and community-based partners. 4) Catalyze innovative research, including novel drug development and informatics methodologies, with particular focus on bringing innovation to special populations and across the lifespan. 5) Create an efficient clinical trials network, centered at UK, and extending into our partner health care systems that will be an essential and leading component of the CTSA consortium, involving participants throughout a four state region of rural Central Appalachia. The UK CCTS benefits from a collaborative environment found on only a few university campuses. UK has 16 colleges, with 11 involved in the UK CCTS (including six biomedical colleges) on one central campus. This physical proximity of our academic and health care communities, along with a culture of collaboration, creates a closely knit unified academic community and positions the UK CCTS to demonstrate the impact of collaborative translational research and leadership in team science. Our efforts have already been successful at transforming the culture of the UK academic medical center to one that more keenly appreciates scholarship, innovation and translational science. We now plan to build on these strengths to advance translational science to the next level, with further development of our clinical trial networks, development of novel informatics programs, and continued development of the workforce throughout the region. These efforts will benefit the medically underserved residents of Central Appalachia and will significantly contribute to the national CTSA program. 1 Project Summary/Abstract Page 287 Contact PD/PI: Kern, Philip A

联系PD/PI：Kern，Philip A 项目摘要肯塔基大学（英国）临床与转化科学中心（CCTS）创建了一个整合临床和翻译研究的综合之家，以促进每个人的科学进步和发现翻译连续体的阶段。 CCT从根本上改变了研究环境仅在英国，但通过建立强大的研究网络的整个阿巴拉契亚中部阿巴拉契亚转化研究网络（ATRN），与包括其他的综合研究合作伙伴关系 CTSA轮毂。结合对独特和严重的健康挑战的深入了解在阿巴拉契亚中部居民面对的情况下，英国CCTS将领导本地，地区和国家研究工作的重点是该人群的重大健康差异。我们作为一个总体目标 CTSA枢纽将继续在临床和翻译研究中倡导创新教育未来的劳动力，使我们的社区参与生物医学科学，并与国家网络促进凝聚力多中心临床试验，最终将提高健康状况和阿巴拉契亚中部民众的生活质量。具体而言，英国CCT将：1）领导机构提供有效，有效的临床和翻译研究的创新。 2）发展潜水员跨多个学科的劳动力，这些学科都会推进转化研究，并在基于团队的科学中表现出色。 3）通过广泛参与和与我们的合作，满足中央阿巴拉契亚中央居民的独特需求区域，农村和社区合作伙伴。 4）催化创新研究，包括新药物开发和信息效应方法论，特别关注将创新带给特殊人群以及整个生命周期。 5）创建一个有效的临床试验网络，以英国为中心，并延伸到我们的合作伙伴卫生保健系统将是CTSA财团的绝对且领先的组成部分，涉及整个阿巴拉契亚州中部四个州地区的参与者。英国CCTS受益于合作环境仅在几个大学校园中找到。英国有16所大学，其中11所参与英国CCT（包括六所生物医学学院）位于一个中央校园。我们的这种身体接近学术和卫生保健社区以及一种合作文化，创造了一个紧密的编织统一学术界并定位英国CCT，以展示协作翻译的影响团队科学的研究和领导。我们的努力已经成功地改变了文化英国学术医学中心的一个更热衷于科学，创新和翻译科学。现在，我们计划以这些优势为基础，将转化科学推向下一个级别，随着我们临床试验网络的进一步发展，新的信息计划的发展以及整个地区劳动力的持续发展。这些努力将在医学上受益服务欠佳的阿巴拉契亚中部居民将为国家CTSA计划做出重大贡献。 1 项目摘要/摘要页面287 联系PD/PI：Kern，Philip A