Kentucky Center for Clinical and Translational Science

肯塔基州临床和转化科学中心

• 批准号: 10733214
• 负责人: Philip A Kern
• 金额: $ 17.5万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10733214
• 关键词: Address; Adolescence; Adult; Age; Air Pollution; Appalachian Region; Automobile Driving; Award; Back; Body mass index; Cardiovascular system; Child; Childhood; Clinic Visits; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Collection; Communication; Communities; Community Healthcare; Development; Diabetes Mellitus; Diagnosis; Discipline; Disparity; Distress; Drowsiness; Economics; Elderly; Environment; Environmental Exposure; Environmental Pollutants; Environmental Risk Factor; Epidemic; Epidemiology; Exposure to; Fostering; Frequencies; Future; Generations; Glycosylated hemoglobin A; Goals; Hair; Health; Health Disparities Research; Health Status; Healthcare; Heavy Metals; Home; Individual; Institution; Integrated Health Care Systems; Joints; Kentucky; Lead; Leg Cramp; Letters; Life Cycle Stages; Link; Literature; Longevity; Malignant Neoplasms; Measurement; Measures; Metal exposure; Metals; Mission; Modeling; Neurosciences; Obesity; Occupational; Outcome; Outcome Study; Parasomnias; Participant; Patient Self-Report; Pediatric cohort; Persons; Phase; Population; Positioning Attribute; Prevalence; Process; Quality of life; Questionnaires; Recommendation; Recording of previous events; Reporting; Research; Role; Rural; Rural Appalachia; Rural Community; Rural Health; School-Age Population; Science; Serum; Sleep; Sleep Apnea Syndromes; Sleep Deprivation; Sleep Disorders; Sleep disturbances; Smoke; Smoking; Snoring; Statistical Methods; Structure of nail of toe; Substance abuse problem; Symptoms; Syndrome; Translational Research; Underserved Population; United States; Universities; Update; West Virginia; Whole Blood; Work; cardiometabolism; clinical center; cohort; community based participatory research; community engagement; deciduous tooth; diversity and inclusion; early life exposure; environmental tobacco smoke; environmental tobacco smoke exposure; health disparity; health equity; health inequalities; improved; innovation; new technology; obesity in children; obesity risk; opioid abuse; parent grant; patient engagement; poor sleep; preadolescence; programs; rural area; rural dwellers; sleep behavior; sleep health; sleep onset; social factors; urinary; web site

PARENT GRANT PROJECT SUMMARY - OVERALL The University of Kentucky (UK) Center for Clinical and Translational Science (CCTS) has created an integrated home for clinical and translational research which promotes scientific progress and discoveries at every phase of the translational continuum. The CCTS has partnered with communities in Central Appalachia to address multiple generations of recalcitrant health inequities related in part to the economic distress of rural communities. The CCTS has fundamentally transformed UK and Central Appalachia through the development of strong academic-community research networks and collaborations within the CTSA consortium. Appalachian health disparities are further magnified by the opioid and substance abuse epidemic, which has greatly impacted eastern Kentucky and West Virginia. The strong UK research portfolio puts the UK CCTS in an optimal position to lead local, regional and national research efforts focused on rural health inequities. The aligned missions of UK, UK HealthCare and the CCTS focus on achieving health equity by engaging in highly innovative, collaborative and dynamic translational research to address rural health needs. The CCTS will continue to educate the translational workforce of the future, engage rural communities in translational and bi-directional team science and work with the national network to advance transdisciplinary research and clinical trials through the following Specific Aims: 1) develop, innovate and transform our research environment to promote impactful science and discovery within our integrated health care system to meet the unique health needs of Central Appalachian residents; 2) lead institutional innovation in the delivery of impactful clinical and translational research that covers the lifespan, fully engages the community and embraces team science; 3) catalyze an efficient, university-wide clinical trials organization which adds value to the CTSA consortium by engaging participants from rural Central Appalachia; and 4) foster and enhance a workforce characterized by diversity and inclusivity across all translational science disciplines and populations. The UK CTSA hub is uniquely positioned in the National CTSA Consortium to foster novel technologies, team science, clinical trial start-up and cutting-edge translational research across the lifespan with a focus on rural communities. We have a particular focus on the Central Appalachian community, a rural area with many of the highest levels of health disparities in the nation. This focus will ultimately elevate the health and quality of life of rural communities throughout the United States.

家长奖助金计划摘要-整体

项目成果

Social Determinants of Health Factors for Gene-Environment COVID-19 Research: Challenges and Opportunities.

• DOI: 10.1002/ggn2.202100056
• 发表时间: 2022-06
• 期刊: Advanced genetics (Hoboken, N.J.)
• 作者: Phuong, Jimmy;Riches, Naomi O;Madlock-Brown, Charisse;Duran, Deborah;Calzoni, Luca;Espinoza, Juan C;Datta, Gora;Kavuluru, Ramakanth;Weiskopf, Nicole G;Ward-Caviness, Cavin K;Lin, Asiyah Yu
• 通讯作者: Lin, Asiyah Yu

Abuse-Deterrent Opioids: A Survey of Physician Beliefs, Behaviors, and Psychology.

• DOI: 10.1007/s40122-021-00343-z
• 发表时间: 2022-03
• 期刊: Pain and therapy
• 影响因子: 4
• 作者: Dasgupta N;Brown JR;Nocera M;Lazard A;Slavova S;Freeman PR
• 通讯作者: Freeman PR

A survey of the barriers associated with academic-based cancer research commercialization.

• DOI: 10.1371/journal.pone.0072268
• 发表时间: 2013
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Vanderford NL;Weiss LT;Weiss HL
• 通讯作者: Weiss HL

Reported Barriers to Hepatitis C Treatment among Pregnant and Early-Parenting Mothers Undergoing Substance Use Disorder Treatment in One U.S. State.

• DOI: 10.3390/idr14010001
• 发表时间: 2021-12-22
• 期刊: Infectious disease reports
• 影响因子: 3.2
• 作者: Adekunle AD;Harp KL;Al-Abdali ZG;Critchfield AS;Barnhart S;Winter KT
• 通讯作者: Winter KT

Vancomycin Dosing Practices among Critical Care Pharmacists: A Survey of Society of Critical Care Medicine Pharmacists.

• DOI: 10.1177/1178633720952078
• 发表时间: 2020
• 期刊: Infectious diseases
• 影响因子: 5.8
• 作者: Flannery AH;Hammond DA;Oyler DR;Li C;Wong A;Smith AP;Yeo QM;Chaney W;Pfaff CE;Plewa-Rusiecki AM;Juang P
• 通讯作者: Juang P