Data Lakes Meet the Great Lakes: Deep Dives into Diversity in Genomics

项目总结 北海岸精准医学会议是一年一度的全国中型会议系列会议，在 俄亥俄州克利夫兰。该系列会议旨在成为持续教育和交流的场所。 与快速发展和高度跨学科的前景相关的科学思想，即精确医学 研究。每次会议的议题都与由 国家研究项目的重点是精准医学。2020年和2021年大会将是专题讨论会 侧重于与翻译遗传和基因组研究有关的广泛主题，包括结构和 基因组生物学；疾病生物学；生物信息学；计算生物学；基因组学在 改善临床护理；以及伦理、法律和社会问题(ELISI)。所有选定的研讨会主题将包括 在研究中强调不同的人群，包括确定和保留参与者 发展混合种群分析方法的策略。这次会议将作为一个 传统的形式，邀请来自国家专家的演讲者在放松和鼓舞人心的环境中演讲 在克利夫兰植物园。正在考虑以前的研讨会中的特定会议主题 精准医学研究的与会者和趋势。单数年会议包括一个研讨会或 之前已涵盖结果和暴露变量提取的小组活动组件 研讨会前后的电子健康记录和与会者知识的实时调查。未来 正在审议的研讨会主题包括多种组学的整合、不同人群中的药物反应、 药物基因组学临床实施，癌症精准医学，数据共享和知情同意， 以及使用APP进行招募、诊断、随访和治疗。我们的第二个主要目标是 系列会议是促进生物医学工作人员多样性的会议。众所周知，这条管道 从生物医学研究的女性培训到正教授是漏洞百出的，而在生物医学研究领域， 有代表性的少数族裔实际上是不存在的。从国家和地方来源来看，我们审查妇女和 代表不足的少数族裔为每个受邀的演讲者机会，从而提供宝贵的职业货币 和网络机会。我们还将鼓励妇女和代表性不足的少数群体，特别是在 实习生层面，出席并参与这一系列会议，以激发人们对研究遗传学和 把基因组学研究作为一种职业。总体而言，北海岸精准医学会议系列是一个有价值的 除了国家会议景观，凭借其独特的地理位置，与会者的低成本，以及差旅 奖项，将成为一个重要的教育机会，因为精确医学研究在 诚挚的。

PROJECT SUMMARY The North Coast Conference on Precision Medicine is a national annual mid-sized conference series held in Cleveland, Ohio. The conference series aims to serve as a venue for the continuing education and exchange of scientific ideas related to the rapidly evolving and highly interdisciplinary landscape that is precision medicine research. The topics for each conference coincide with the national conversation and research agenda set by national research programs focused on precision medicine. The 2020 and 2021 conferences will be symposia focused on broad themes relevant to translational genetic and genomic research, including the structure and biology of genomes; the biology of disease; bioinformatics; computational biology; application of genomics to improve clinical care; and ethical, legal and social issues (ELISI). All selected symposium topics will include an emphasis on diverse populations in research, which can range from ascertainment and participant retention strategies to methods development for analysis of admixed populations. The conference will be organized as a traditional format with invited speakers from among national experts set in a relaxing and inspiring environment at the Cleveland Botanical Garden. Specific conference topics are being considered from previous symposia attendees and trends in precision medicine research. Odd-numbered year conferences include a workshop or group activity component which has previously covered outcome and exposure variable extraction from electronic health records and real-time survey of attendee knowledge pre- and post-symposium. Future workshop topics being considered include integration of multiple ‘omics, drug response in different populations, pharmacogenomics clinical implementation, precision medicine in cancer, data sharing and informed consent, and the use of apps for recruitment, diagnosis, follow-up, and treatment. Our second major objective of this conference series is the promotion of diversity in the biomedical workforce. It is well-known that the pipeline from training to full professor for women in biomedical research is leaky whereas the pipeline for under- represented minorities is practically non-existent. Drawing from national and local sources, we vet women and under-represented minorities for every invited speaker opportunity, thereby providing valuable career currency and networking opportunities. We will also encourage women and under-represented minorities, particularly at the trainee level, to attend and participate in this conference series to spur interest in pursuing genetics and genomics research as a career. Overall, the North Coast Conference on Precision Medicine series is a valuable addition to the national conference landscape, and with its unique location, low cost to participants, and travel awards, will serve as an important educational opportunity as precision medicine research accelerates in earnest.