Proteomics Laboratory Shared Resources

蛋白质组学实验室共享资源

• 批准号: 10358547
• 负责人: Beatrix Magdalena Ueberheide
• 金额: $ 6.52万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10358547
• 关键词: Biochemistry; Biological; Cancer Center; Cancer Center Support Grant; Collaborations; Custom; Data Analyses; Doctor of Philosophy; Education; Educational process of instructing; Ensure; Experimental Designs; Individual; Label; Laboratories; Mass Spectrum Analysis; Mission; Molecular; Paper; Peptides; Pharmacology; Post-Translational Protein Processing; Postdoctoral Fellow; Preparation; Protein Analysis; Proteomics; Proteomics Shared Resource; Publications; Research; Research Personnel; Resource Sharing; Resources; Sampling; Scientist; Students; Technical Expertise; Techniques; Technology; Training; base; data analysis pipeline; experience; graduate student; hands on instruction; innovation; instrumentation; member; method development; novel; operation; professor; protein complex

Abstract/Project Summary PROTEOMICS RESOURCE LABORATORY SHARED RESOURCE (PRL) The Proteomics Resource Laboratory (PRL) provides support for mass spectrometry-based proteomics analysis for all Perlmutter Cancer Center (PCC) investigators through a centralized facility, with state-of-the-art instrumentation and highly specialized technical expertise. Under the direction of Dr. Beatrix Ueberheide, a well-established expert in biological mass spectromety, PRL was established 5 years ago to expand upon the successful Proteomics Core. PRL aids scientific discovery at PCC by providing access to specialized expertise and state-of-the-art instrumentation for the analysis of proteins and peptides using mass spectrometry (MS). A special focus of the laboratory is assistance with experimental design and full support for downstream data analysis, often involving innovative data analysis pipelines. Significant economies of scale are achieved by this centralization of resources. PRL achieves its mission via four Specific Aims: Aim 1) To provide mass spectrometry-based, state-of-the-art proteomics technologies to PCC investigators and full downstream data analysis support; Aim 2) To provide highly customized support tailored to specific projects and research questions of PCC investigators; Aim 3) To develop and implement novel techniques to ensure continued support of state-of-the-art proteomics technology for PCC investigators; Aim 4) To provide education to graduate students and post-doctoral researchers on proteomics techniques through graduate teaching and close collaboration with PCC investigators.

抽象/项目总结