The Mayo Clinic IMSD: Developing scientists through disease-relevant research

梅奥诊所 IMSD：通过疾病相关研究培养科学家

• 批准号: 10359100
• 负责人: Luis Lujan
• 金额: $ 47.66万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-30 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10359100
• 关键词: Achievement; Arizona; Association of American Medical Colleges; Award; Biomedical Research; Clinic; Communication; Disabled Persons; Disease; Diverse Workforce; Doctor of Philosophy; Educational Curriculum; Educational process of instructing; Ensure; Environment; Extramural Activities; Fellowship; Florida; Funding; Future; Goals; Grant; Hour; Individual; International; Internships; Investments; Lead; Leadership; Mentors; Minnesota; Minority Groups; Monitor; Oral; Paper; Positioning Attribute; Postdoctoral Fellow; Preparation; Publications; Publishing; Qualifying; Research; Research Project Grants; Running; Schools; Scientist; Self Efficacy; Social support; Students; Training; Training Support; Underrepresented Students; United States National Institutes of Health; base; career; career development; college; disadvantaged background; doctoral student; education research; experience; graduate student; improved; meetings; novel; outreach; peer coaching; pre-doctoral; programs; racial and ethnic; recruit; skill acquisition; skills; skills training; student training; success; symposium; undergraduate student

The long-running and successful IMSD at Mayo Graduate School (MGS) will maintain and advance its proven approaches to promoting the success of students from backgrounds historically underrepresented (UR) in careers that promote biomedical research. We propose renewed funding to achieve the following four specific aims: Aim 1: Recruit and matriculate 4/5 (alternating) new UR IMSD PhD students each year during grant years 22 – 26 to participate in IMSD for the first 2 years of their PhD training (supporting 9 students per year). This tactic has the potential to assure at least 15% UR students in MGS entering classes Aim 2: Maintain an excellent, evaluated curriculum of independent research, communication skills training, near-peer mentoring, and social support. Achievement of PhD milestones such as passing qualifying exams, completion of PhD, publications, presentations, and fellowship awards will be monitored. Aim 3: Involve IMSD students in organizing a biennial Mayo-hosted IMSD/PREP scientific conference including IMSD recruitment outreach to pipeline undergrad/post-baccalaureate programs. Students lead in all aspects of conference organization and management developing leadership skills and promoting self-efficacy. Aim 4: Expose IMSD students to MGS Career Development Internships (CDI) during graduate school years 1-2. IMSD familiarizes students with biomedical research careers different from those of their mentors Our experience shows that the central focus for success is an excellent mentored PhD thesis research project. As Alex Ommaya, acting chief scientific officer of the Association of American Medical Colleges has stated, a key focus for the future must also be to "...ensure that graduate students are trained in skills such as communication, teaching, management, and teamwork..." We completely agree, and these goals are reflected in the four specific aims of our renewal proposal. Aims 1-2 are based on experience gained from analysis of 21 years of IMSD programming at MGS and will sustain and improve the proven tactics that form the core impact of the MGS IMSD. Aims 3 and 4 bring creative and novel experiences to IMSD students, and are both based on extremely successful pilot programs, assuring them of success and high impact.

长期运行和成功的IMSD在马约研究生院（MGS）将保持和推进 其行之有效的方法，以促进学生的成功，从历史背景 在促进生物医学研究的职业中代表性不足（UR）。我们建议重新提供资金， 实现以下四个具体目标： 目标1：在赠款年，每年招收4/5（交替）新的UR IMSD博士生 22 - 26参加IMSD为他们的博士培训的前2年（每年支持9名学生）。 这一策略有可能确保至少15%的UR学生在MGS进入班级 目标2：保持一个优秀的，独立研究，沟通技能培训， 同伴指导和社会支持。 实现博士学位的里程碑，如通过资格考试，完成博士学位，出版物， 将对专题介绍和研究金发放情况进行监测。 目标3：让IMSD学生参与组织由梅奥主办的两年一次的IMSD/PREP科学会议 包括IMSD招聘推广管道本科/学士后课程。 学生领导会议组织和管理的各个方面，发展领导技能， 提高自我效能。 目标4：使IMSD学生在研究生学习期间参加MGS职业发展实习（CDI） 1-2. IMSD使学生熟悉与导师不同的生物医学研究职业 我们的经验表明，成功的中心焦点是一个优秀的指导博士论文 研究项目。作为美国医学协会代理首席科学官亚历克斯·奥马亚， 学院表示，未来的一个关键重点也必须是"......确保研究生得到培养 沟通、教学、管理和团队合作等技能。"我们完全同意，这些 这些目标反映在我们更新建议的四个具体目标中。目标1 - 2基于经验 从MGS 21年的IMSD编程分析中获得，并将维持和改进已证明的 形成MGS IMSD核心影响的战术。目标3和4为您带来创新的体验， IMSD的学生，都是基于非常成功的试点计划，确保他们的成功， 高影响。

项目成果

The pathology of multiple sclerosis: evidence for heterogeneity.

• 发表时间: 2006
• 期刊: Advances in neurology
• 作者: Y. Morales;J. Parisi;C. Lucchinetti

Apoptosis by gel-entrapped hepatocytes in a bioartificial liver.

生物人工肝中凝胶包埋的肝细胞发生细胞凋亡。

• DOI: 10.1016/s0041-1345(98)01743-6
• 发表时间: 1999
• 期刊: Transplantation proceedings
• 影响因子: 0.9
• 作者: Rivera,DJ;Gores,GJ;Misra,SP;Hardin,JA;Nyberg,SL
• 通讯作者: Nyberg,SL

A neurochemical closed-loop controller for deep brain stimulation: toward individualized smart neuromodulation therapies.

• DOI: 10.3389/fnins.2014.00169
• 发表时间: 2014
• 期刊: Frontiers in neuroscience
• 影响因子: 4.3
• 作者: Grahn PJ;Mallory GW;Khurram OU;Berry BM;Hachmann JT;Bieber AJ;Bennet KE;Min HK;Chang SY;Lee KH;Lujan JL
• 通讯作者: Lujan JL

Retargeted and detargeted adenovirus for gene delivery to the muscle.

• DOI: 10.1016/j.virol.2017.10.005
• 发表时间: 2018-01-15
• 期刊: Virology
• 影响因子: 3.7
• 作者: Nguyen TV;Anguiano-Zarate SS;Matchett WE;Barry ME;Barry MA
• 通讯作者: Barry MA

Identifying future scientists: predicting persistence into research training.

• DOI: 10.1187/cbe.07-04-0020
• 发表时间: 2007-01-01
• 期刊: CBE life sciences education
• 作者: McGee, Richard;Keller, Jill L
• 通讯作者: Keller, Jill L