VCU Massey Cancer Center Minority/Underserved NCI Community Oncology Research Program

VCU 梅西癌症中心少数族裔/服务不足的 NCI 社区肿瘤​​学研究计划

• 批准号: 10456776
• 负责人: HARRY D BEAR
• 金额: $ 118.07万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10456776
• 关键词: Address; Adult; African American population; American College of Radiology Imaging Network; Ancillary Study; Area; Award; Cancer Center; Cancer Control; Cancer Control Research; Cancer Patient; Caring; Catchment Area; Childhood; Clinical; Clinical Research; Clinical Treatment; Clinical Trials; Collection; Colorectal Cancer; Communities; Community Clinical Oncology Program; Community Practice; Detection; Development; Eastern Cooperative Oncology Group; Educational Background; Enrollment; Ethnic group; Feedback; Funding; Geography; Goals; Gynecologic; Health Personnel; Human Resources; Image; Incidence; Individual; Lead; Low income; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of prostate; Measures; Medical Oncologist; Minority; Minority Groups; Minority-Based Community Clinical Oncology Program; Mission; Oncologist; Oncology; Outcome; Participant; Patients; Pediatric Oncology Group; Personal Satisfaction; Phase; Population; Prevention; Prevention Research; Primary Health Care; Prognosis; Protocols documentation; Public Health; Quality of life; Radiation Oncologist; Recording of previous events; Research; Research Personnel; Resources; Rural; Rural Community; Rural Population; Science; Site; Socioeconomic Factors; Specialist; Surgeon; Underserved Population; Universities; Urban Population; Virginia; anticancer research; base; biobank; cancer care; cancer clinical trial; cancer health disparity; cancer prevention; cancer therapy; care delivery; clinical trial enrollment; clinically significant; demographics; ethnic minority population; experience; forest; health care disparity; improved; insight; interest; malignant breast neoplasm; malignant stomach neoplasm; medically underserved; member; minority patient; mortality; outreach; programs; protocol development; racial and ethnic; racial and ethnic disparities; research study; rural African American; rural patients; screening; socioeconomic disparity; treatment research; treatment trial; underserved community; underserved minority

PROJECT SUMMARY Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) will serve as the primary component site for an NCORP Minority/Underserved Community Site (MU-NCORP) UG1 award in partnership with 6 collaborating community affiliate sites in the Commonwealth of Virginia. Over 30% of patients seen in the MCC MU-NCORP are from minority populations, primarily African Americans. This proposal emphasizes the unique urban and rural population available to the MCC MU-NCORP, the history of extensive participation by primary health care providers and specialists, in particular, surgeons, pediatric/AYA oncologists, gynecologic surgeons, radiation oncologists, neuro-oncologists, and medical oncologists in clinical research, and VCU initiatives in cancer outreach conducted at rural sites across Virginia. This community-based NCORP, focused on participation in clinical research of minority populations, was initially funded as a Minority-Based Community Clinical Oncology Program in 1990 and has been continuously funded, including since 2014 as a MU-NCORP. The MCC MU-NCORP has affiliations with 5 Research Bases (Alliance for Clinical Trials in Oncology, Children’s Oncology Group, ECOG-ACRIN Cancer Research Group, NRG Oncology, and the Wake Forest NCORP Research Base). Our application describes the working relationships with the Research Bases and the focus of the MCC MU-NCORP to accrue significant numbers of minority participants in cancer control and prevention, treatment/imaging, and cancer care delivery clinical research studies. Working relationships of the primary site’s investigators, research staff, and support personnel with the affiliate sites are also described. Accordingly, the specific aims of this proposal are (1) to increase the overall enrollment of racial/ethnic and rural populations in our catchment areas to NCI-approved studies, with a greater focus on cancer control research, cancer prevention research, and cancer care delivery research (CCDR), in addition to cancer treatment research; (2) to collaborate with the NCORP Research Bases by (i) providing insight into relevance for community practices during concept development, (ii) identifying care disparities our catchment areas that should be studied, and (iii) providing input on feasibility during concept and protocol development; (3) to exceed the required annual minimum participation in CCDR protocols; (4) to participate in biospecimen collection for biobanks that serve as scientific resources for NCORP Research Bases; and (5) to participate in NCORP initiatives, such as DCP-001, to document screening efforts for clinical trial enrollment and to address cancer health disparities. The proposed research is relevant to the mission of the NCI as MCC and the community affiliates will bring cancer clinical trials and research to low-income, minority, and medically underserved individuals who otherwise would not have access to such studies. Targeting the minority/underserved populations in their communities is a critical step toward alleviating the cancer care disparities prevalent in these populations.

项目概要 弗吉尼亚联邦大学 (VCU) 梅西癌症中心 (MCC) 将作为主要组成部分 与 6 家合作获得 NCORP 少数族裔/服务欠缺社区网站 (MU-NCORP) UG1 奖的网站 弗吉尼亚联邦的合作社区附属网站。超过 30% 的患者在 MCC 就诊 MU-NCORP 来自少数族裔，主要是非裔美国人。该提案强调了独特的 MCC MU-NCORP 可利用的城乡人口，小学广泛参与的历史 医疗保健提供者和专家，特别是外科医生、儿科/AYA 肿瘤科医生、妇科医生、 临床研究中的放射肿瘤学家、神经肿瘤学家和医学肿瘤学家，以及 VCU 的倡议 在弗吉尼亚州各地的农村地区开展癌症外展活动。这个以社区为基础的 NCORP，专注于 参与少数民族人口的临床研究，最初是作为少数民族社区资助的 临床肿瘤学项目于 1990 年启动，并持续获得资助，包括自 2014 年起作为 MU-NCORP。 MCC MU-NCORP 拥有 5 个研究基地（肿瘤临床试验联盟、 儿童肿瘤学小组、ECOG-ACRIN 癌症研究小组、NRG 肿瘤学和维克森林大学 NCORP 研究基地）。我们的申请描述了与研究基地的工作关系和 MCC MU-NCORP 的重点是吸引大量少数族裔参与者参与癌症控制和 预防、治疗/成像和癌症护理提供临床研究。的工作关系 还描述了主站点的调查员、研究人员和附属站点的支持人员。 因此，该提案的具体目标是 (1) 增加种族/族裔和 我们流域的农村人口接受 NCI 批准的研究，重点关注癌症控制 除癌症之外，研究、癌症预防研究和癌症护理提供研究 (CCDR) 治疗研究； (2) 通过 (i) 提供相关性见解与 NCORP 研究基地合作 对于概念制定过程中的社区实践，(ii) 确定我们的服务区域的护理差异， 应进行研究，以及 (iii) 在概念和协议制定过程中提供可行性意见； (3) 至 超过 CCDR 协议规定的年度最低参与人数； (4) 参加生物样本 生物库的收集，作为 NCORP 研究基地的科学资源； (5) 参与 NCORP 举措，例如 DCP-001，用于记录临床试验注册的筛选工作并解决 癌症健康差异。 拟议的研究与 NCI 的使命相关，因为 MCC 和社区附属机构将带来 针对低收入、少数族裔和医疗服务不足的个人的癌症临床试验和研究 否则将无法获得此类研究。针对少数民族/服务不足的人群 社区是缓解这些人群中普遍存在的癌症护理差异的关键一步。