Leveraging biomarkers for personalized treatment of alcohol use disorder comorbid with PTSD

利用生物标志物对合并 PTSD 的酒精使用障碍进行个性化治疗

• 批准号: 10473675
• 负责人: Charles R. Marmar
• 金额: $ 9.96万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-20 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10473675
• 关键词: Accountability; Adherence; Alcohol Phenotype; Animal Model; Biological Markers; Biostatistics Core; Blood; Budgets; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Committee Members; Communication; Data; Development; Elements; Ensure; Evaluation; Extramural Activities; Faculty; Fostering; Goals; Human Resources; Image; Infrastructure; Interdisciplinary Study; Investigation; K-Series Research Career Programs; Logistics; Mentors; Mentorship; Occupational activity of managing finances; Office of Administrative Management; Persons; Policies; Post-Traumatic Stress Disorders; Productivity; Public Health; Publications; Research; Research Activity; Research Personnel; Research Project Grants; Resource Sharing; Resources; Schedule; Services; Site; TimeLine; United States National Institutes of Health; Update; alcohol comorbidity; alcohol use disorder; career; career development; clinical practice; comorbidity; design; improved; insight; medical schools; meetings; member; neural circuit; personalized medicine; posters; programs; symposium; synergism; traumatic stress; visiting scholar

Summary The Administrative Core for the NYU Langone Center for the Study of Alcohol Use Disorder and Traumatic Stress will oversee the planning, development, coordination, evaluation, and overall administration of all research activities across the three Projects and two Resource Cores. Dr. Charles Marmar, MD will be the Director of the Admininstrative Core. Drs. Arieh Shalev, MD and John Rotrosen, MD will serve as Deputy Directors. A Program Advisory Board, comprising five leading researchers whose collective expertise aligns closely with all aspects of the Center’s objectives, will provide extramural evaluation of progress and guidance to optimize productivity. The specific aims of this Core are to: 1) provide oversight for operational integration of the three Projects and two Resource Cores; 2) facilitate meaningful interactions and communication among the Center personnel and the Program Advisory Board; 3) centralize services that ensure compliance with NIH policy requirements for management of fiscal, personnel, and regulatory functions of the Center; and 4) foster translational, interdisciplinary research on the comorbidity of alcohol use disorder and post-traumatic stress disorder at the NYU School of Medicine. The leaders of each project and core will meet with their staff every week. Dr. Marmar will chair monthly meetings of the entire Center research team and quarterly meettings of the Steering Committee. The Program Advisory Board will meet with Center Directors and Project and Core Leads every 6 months to evaluate the progress of each project and adherence to milestones and timelines, and provide updates. This will ensure that all Center activities remain both on schedule and on budget. An Enrichment Program will invite visiting scholars to present seminars and to interact with members of the Center. Hence, the Adminstrative Core will establish and maintain policies for prudent financial management, ensure regulatory compliance, maximize efficient use and sharing of resources provided by the Cores, and promote synergistic integration across the Projects.

总结 纽约大学朗格尼酒精使用障碍和创伤性精神障碍研究中心（NYU Langone Center for the Study of Alcohol Use Disorder and Traumatic Stress将监督所有项目的规划、开发、协调、评估和总体管理。 三个项目和两个资源核心的研究活动。Charles Marmar博士，医学博士将是 行政核心主任。Arieh Shalev博士和John Rotrosen博士将担任副主席 董事们。一个项目咨询委员会，由五位领先的研究人员组成，他们的集体专业知识与 紧密结合中心各方面的目标，将为校外评估工作的进展提供指导 以优化生产力。本核心的具体目标是：1）监督 三个项目和两个资源核心; 2）促进 中心人员和项目咨询委员会; 3）集中服务，确保符合NIH 中心的财政、人事和监管职能管理的政策要求; 4）促进 关于酒精使用障碍和创伤后应激障碍共病的跨学科转化研究 纽约大学医学院的一名学生每个项目和核心的领导人将与他们的工作人员会面， 周Marmar博士将主持整个中心研究团队的月度会议和以下人员的季度会议： 指导委员会。项目咨询委员会将与中心主任、项目和核心成员会面。 领导每6个月评估每个项目的进展情况，并遵守里程碑和时间表， 并提供更新。这将确保中心的所有活动都按计划和预算进行。一个 丰富计划将邀请访问学者出席研讨会，并与成员互动， 中心因此，行政核心将制定和维持审慎的财务管理政策， 确保合规性，最大限度地有效利用和共享核心所提供的资源，以及 促进项目之间的协同整合。