Leveraging biomarkers for personalized treatment of alcohol use disorder comorbid with PTSD

利用生物标志物对合并 PTSD 的酒精使用障碍进行个性化治疗

• 批准号: 10473675
• 负责人: Charles R. Marmar
• 金额: $ 9.96万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-20 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10473675
• 关键词: Accountability; Adherence; Alcohol Phenotype; Animal Model; Biological Markers; Biostatistics Core; Blood; Budgets; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Committee Members; Communication; Data; Development; Elements; Ensure; Evaluation; Extramural Activities; Faculty; Fostering; Goals; Human Resources; Image; Infrastructure; Interdisciplinary Study; Investigation; K-Series Research Career Programs; Logistics; Mentors; Mentorship; Occupational activity of managing finances; Office of Administrative Management; Persons; Policies; Post-Traumatic Stress Disorders; Productivity; Public Health; Publications; Research; Research Activity; Research Personnel; Research Project Grants; Resource Sharing; Resources; Schedule; Services; Site; TimeLine; United States National Institutes of Health; Update; alcohol comorbidity; alcohol use disorder; career; career development; clinical practice; comorbidity; design; improved; insight; medical schools; meetings; member; neural circuit; personalized medicine; posters; programs; symposium; synergism; traumatic stress; visiting scholar

Summary The Administrative Core for the NYU Langone Center for the Study of Alcohol Use Disorder and Traumatic Stress will oversee the planning, development, coordination, evaluation, and overall administration of all research activities across the three Projects and two Resource Cores. Dr. Charles Marmar, MD will be the Director of the Admininstrative Core. Drs. Arieh Shalev, MD and John Rotrosen, MD will serve as Deputy Directors. A Program Advisory Board, comprising five leading researchers whose collective expertise aligns closely with all aspects of the Center’s objectives, will provide extramural evaluation of progress and guidance to optimize productivity. The specific aims of this Core are to: 1) provide oversight for operational integration of the three Projects and two Resource Cores; 2) facilitate meaningful interactions and communication among the Center personnel and the Program Advisory Board; 3) centralize services that ensure compliance with NIH policy requirements for management of fiscal, personnel, and regulatory functions of the Center; and 4) foster translational, interdisciplinary research on the comorbidity of alcohol use disorder and post-traumatic stress disorder at the NYU School of Medicine. The leaders of each project and core will meet with their staff every week. Dr. Marmar will chair monthly meetings of the entire Center research team and quarterly meettings of the Steering Committee. The Program Advisory Board will meet with Center Directors and Project and Core Leads every 6 months to evaluate the progress of each project and adherence to milestones and timelines, and provide updates. This will ensure that all Center activities remain both on schedule and on budget. An Enrichment Program will invite visiting scholars to present seminars and to interact with members of the Center. Hence, the Adminstrative Core will establish and maintain policies for prudent financial management, ensure regulatory compliance, maximize efficient use and sharing of resources provided by the Cores, and promote synergistic integration across the Projects.

摘要 纽约大学朗格尼酒精使用障碍和创伤研究中心的行政核心 压力将监督所有部门的规划、发展、协调、评估和全面管理 三个项目和两个资源核心的研究活动。查尔斯·马马尔博士将成为 行政核心主管。医学博士Arieh Shalev和医学博士John Rotrosen将担任副手 董事们。计划咨询委员会，由五名领先的研究人员组成，他们的集体专长与 密切配合中心所有方面的目标，将提供对进展和指导的外部评价 以优化工作效率。该核心的具体目标是：1)监督业务整合 三个项目和两个资源核心；2)促进有意义的互动和沟通 中心人员和计划咨询委员会；3)集中服务，确保符合NIH 中心财政、人事和监管职能管理的政策要求；以及4)促进 酒精使用障碍和创伤后应激障碍共病的跨学科翻译研究 纽约大学医学院的混乱。每个项目和核心的领导将在每年 星期。Marmar博士将主持整个中心研究团队的每月会议和季度会议 指导委员会。计划咨询委员会将与中心主任以及项目和核心部门会面 每6个月领导一次评估每个项目的进度以及对里程碑和时间表的遵守情况 并提供最新信息。这将确保中心的所有活动都按计划和预算进行。一个 丰富计划将邀请访问学者出席研讨会并与 中心。因此，行政核心将制定和维持审慎财务管理政策， 确保合规，最大限度地高效使用和共享核心提供的资源，以及 促进项目之间的协同整合。