Leveraging biomarkers for personalized treatment of alcohol use disorder comorbid with PTSD

利用生物标志物对合并 PTSD 的酒精使用障碍进行个性化治疗

• 批准号: 10473675
• 负责人: Charles R. Marmar
• 金额: $ 9.96万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-20 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10473675
• 关键词: Accountability; Adherence; Alcohol Phenotype; Animal Model; Biological Markers; Biostatistics Core; Blood; Budgets; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Committee Members; Communication; Data; Development; Elements; Ensure; Evaluation; Extramural Activities; Faculty; Fostering; Goals; Human Resources; Image; Infrastructure; Interdisciplinary Study; Investigation; K-Series Research Career Programs; Logistics; Mentors; Mentorship; Occupational activity of managing finances; Office of Administrative Management; Persons; Policies; Post-Traumatic Stress Disorders; Productivity; Public Health; Publications; Research; Research Activity; Research Personnel; Research Project Grants; Resource Sharing; Resources; Schedule; Services; Site; TimeLine; United States National Institutes of Health; Update; alcohol comorbidity; alcohol use disorder; career; career development; clinical practice; comorbidity; design; improved; insight; medical schools; meetings; member; neural circuit; personalized medicine; posters; programs; symposium; synergism; traumatic stress; visiting scholar

Summary The Administrative Core for the NYU Langone Center for the Study of Alcohol Use Disorder and Traumatic Stress will oversee the planning, development, coordination, evaluation, and overall administration of all research activities across the three Projects and two Resource Cores. Dr. Charles Marmar, MD will be the Director of the Admininstrative Core. Drs. Arieh Shalev, MD and John Rotrosen, MD will serve as Deputy Directors. A Program Advisory Board, comprising five leading researchers whose collective expertise aligns closely with all aspects of the Center’s objectives, will provide extramural evaluation of progress and guidance to optimize productivity. The specific aims of this Core are to: 1) provide oversight for operational integration of the three Projects and two Resource Cores; 2) facilitate meaningful interactions and communication among the Center personnel and the Program Advisory Board; 3) centralize services that ensure compliance with NIH policy requirements for management of fiscal, personnel, and regulatory functions of the Center; and 4) foster translational, interdisciplinary research on the comorbidity of alcohol use disorder and post-traumatic stress disorder at the NYU School of Medicine. The leaders of each project and core will meet with their staff every week. Dr. Marmar will chair monthly meetings of the entire Center research team and quarterly meettings of the Steering Committee. The Program Advisory Board will meet with Center Directors and Project and Core Leads every 6 months to evaluate the progress of each project and adherence to milestones and timelines, and provide updates. This will ensure that all Center activities remain both on schedule and on budget. An Enrichment Program will invite visiting scholars to present seminars and to interact with members of the Center. Hence, the Adminstrative Core will establish and maintain policies for prudent financial management, ensure regulatory compliance, maximize efficient use and sharing of resources provided by the Cores, and promote synergistic integration across the Projects.

概括 NYU Langone研究中心饮酒障碍和创伤性研究中心的行政核心 压力将监督所有人的计划，发展，协调，评估和整体管理 这三个项目和两个资源核心的研究活动。医学博士Charles Marmar博士将是 管理核心主任。博士。医学博士Arieh Shalev和医学博士John Rotrosen将担任副手 导演。计划咨询委员会，完成了五位集体专业知识一致的主要研究人员 与中心目标的各个方面紧密相关，将提供进度和指导的壁外评估 优化生产率。该核心的具体目的是：1）提供对操作整合的监督 这三个项目和两个资源核心； 2）促进有意义的互动和交流 中心人员和计划顾问委员会； 3）集中服务以确保符合NIH 对中心的财政，人员和监管职能管理的政策要求； 4）寄养 关于酒精使用障碍和创伤后压力的合并症的翻译，跨学科研究 纽约大学医学院的障碍。每个项目和核心的领导者将与他们的员工会面 星期。 Marmar博士将主持整个中心研究团队的每月会议和季度会议 指导委员会。计划咨询委员会将与中心董事，项目和核心会面 每6个月领导一次，以评估每个项目的进度并遵守里程碑和时间表， 并提供更新。这将确保所有中心活动都按计划和预算保持。一个 丰富计划将邀请访问学者提出下水道，并与成员互动 中心。因此，管理核心将制定并维护审慎财务管理的政策， 确保法规合规性，最大程度地利用和共享核心提供的资源以及 促进整个项目的协同整合。