Pilot and Exploratory Studies Core

总结 佛罗里达大学（UF）老年美国人独立中心（OAIC）试点和探索的目标 研究核心（PESC）是为了帮助规划未来的独立支持的研究，解决用友OAIC的 总体研究主题是促进美国老年人的流动性和独立性。为此中央 PESC征求和选择有前途的创新试点，探索性和发展性研究，并确保 最佳的基础设施、环境、资金、专业知识和资源。核心负责人监控研究进展， 帮助分析和解释结果，并提供指导，将这些试点数据转化为高质量的， 原创研究申请成功竞争独立的校外资金。的 为试点、探索性和发展性研究提供资金，支持早期研究者 努力发展老龄化研究事业。 PESC还允许在老化方面有成就的调查人员收集数据，扩展和拓宽他们的关注点。 在这方面，它鼓励和促进传统上从事其他研究的有经验的调查人员 领域，如生理学，病理学，代谢组学，癌症，疼痛和行为科学，以扩大其 研究包括老化。这扩大了人才库，我们相信这将有助于促进 促进流动性和独立性以及整个独立审计办公室。 在本申请中，我们提出了五项试点研究，这些研究提供了多种跨学科方法， 研究主题OAIC。正如我们在过去几年中所证明的那样，我们在以下方面非常成功： 将我们的试点，探索性和发展研究的结果转化为校外资助的赠款（最多 94%的成功率），并通过职业发展支持我们的早期研究人员，包括 任期和晋升过程。

SUMMARY The goal of the University of Florida (UF) Older Americans Independence Center (OAIC) Pilot and Exploratory Studies Core (PESC) is to help plan future independently supported studies that address the UF OAIC’s overall research theme of promotion of mobility and independence in older Americans. To this end, the PESC solicits and selects promising innovative pilot, exploratory, and developmental studies and secure optimal infrastructure, environment, funding, expertise, and resources. Core leaders monitor study progress, help analyze and interpret results, and provide guidance in translating these pilot data into high-quality and original research study applications that successfully compete for independent extramural funding. The provision of funds for pilot, exploratory, and developmental studies supports Early Stage Investigators in their efforts to develop research careers in aging. The PESC also allows accomplished investigators in aging to gather data that extend and broaden their focus. In this capacity, it encourages and facilitates experienced investigators traditionally working in other research fields, such as physiology, pathology, metabolomics, cancer, pain, and the behavioral sciences, to expand their research to include aging. This widens the pool of talent that we believe will contribute to advances in the promotion of mobility and independence and the OAIC as a whole. In this application we propose five pilot studies that offer a wide variety of interdisciplinary approaches to address the OAIC research theme. As we have proven over the past several years, we are highly successful in translating findings from our pilot, exploratory, and development studies into extramurally funded grants (up to 94% success rates), and also in supporting our Early Stage Investigators through career advances including the tenure and promotion process.