IGNITE KUH NRSA Training Core
IGNITE KUH NRSA Training Core
批准号:
10652651
负责人:
DIDIER PORTILLA
金额:
$38.52万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-09-15 至 2026-05-31
关键词:
Acute Renal Failure with Renal Papillary NecrosisAddressAdultAdvocacyAffectAmericanAnti-Inflammatory AgentsAreaAttenuatedBasic ScienceBenignBioenergeticsBiologyBiomechanicsBiomedical EngineeringBloodBreedingCareer ChoiceChildhoodChronic Kidney InsufficiencyCisplatinClinical ResearchClinical SciencesClinical and Translational Science AwardsCohort StudiesCommunicationCystoscopyData ScienceDendritic CellsDevelopmentDiseaseDoctor of PhilosophyEndotheliumFGF2 geneFacultyFutureGeneral PopulationGoalsHL-60 CellsHealthHealthcare SystemsHematological DiseaseHematologyHistorically Black Colleges and UniversitiesHumanImmunityIndividualInflammationInfrastructureInjuryInstitutionInterferon Type IIKidneyKidney DiseasesLeadLipidsMediatingMedicalMethodsMicrobubblesMitochondriaMole the mammalNational Research Service AwardsNephrologyNephronsNeuroimmuneOperative Surgical ProceduresPathway interactionsPatientsPhysiciansPostdoctoral FellowPredictive AnalyticsPriceRaceRecoveryReperfusion InjuryResearchResearch InstituteResearch PersonnelResearch PriorityResearch TrainingResistanceResuscitationRisk FactorsRoleScientistSelection for TreatmentsSocietiesSphingolipidsSphingosineSphingosine-1-Phosphate ReceptorStudentsSurgeonSystemSystems BiologyTherapeuticTrainingTraining ProgramsTraining and EducationTranslational ResearchUltrasonicsUnderrepresented PopulationsUnderrepresented StudentsUnited StatesUniversitiesUrologic DiseasesUrologyVirginiaWashingtonchemotherapycholinergicclinical centerdiabeticdoctoral studentdrug discoveryfunctional genomicshuman diseaseinnovationkidney fibrosismedical specialtiesnanoparticle deliverynanotherapeuticnext generationnon-diabeticnovelpressurepreventprogramsreceptorrecruitrenal ischemiarosinsphingosine 1-phosphatesphingosine kinasesuccesstargeted deliverytelecaretranslational health sciencetrendultrasoundworkforce needs
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Contact PD/PI: Okusa, Mark D. NRSA-Training-001 (883)
NRSA TRAINING CORE ABSTRACT
The Integrated Virginia Research Training Centers in Kidney, Urology and Hematology (IGNITE
KUH) training program is being proposed to address an unmet need and major gap in prioritized
research training through development and integration of a statewide research program in the
Commonwealth of Virginia. The IGNITE KUH NRSA Training Core is an innovative and distinctive
multi-institutional, multi-departmental program comprising a team of 65 outstanding faculty from
the University of Virginia (UVA), Virginia Commonwealth University (VCU), and Virginia
Polytechnic Institute and State University (VT) with primary research programs anchored in the
basic research and clinical science of benign KUH diseases in six thematic areas: Systems
Biology and Functional Genomics, Immunity and Inflammation, Biomedical Engineering,
Nanotherapeutics and Drug Discovery, Clinical and Data Sciences, and Predictive Analytics. The
NRSA Training Core leverages existing strengths in kidney and hematological disease research,
uniting them with urological disease research in a cohesive, integrated and coordinated research
training program. The NRSA Training Core will be enhanced through participation and integration
of the Translational Health Research Institute of Virginia (iTHRIV), a component of the Clinical
and Translational Science Award (CTSA) partnership between UVA and VT, and the Wright
Center for Clinical and Translational Research (CCTR) at VCU. Three major goals of the IGNITE
KUH NRSA Training Core include: 1) increase training of PhD students, residents (urology) and
postdoctoral fellows in basic and translational aspects of KUH in health and disease using a
unified approach; 2) establish an integrated Virginia-wide research training program focused on
KUH-diseases; and 3) attract outstanding students and postdoctoral fellows with long-term career
interests in basic or clinical research into the IGNITE KUH Training Program. IGNITE KUH will
prioritize strategies to attract students from underrepresented populations at several partner
institutions, including three historically black universities in Virginia – Virginia State University
(VSU), Hampton University (HU), and Virginia Union Universities (VUU) – thereby further
enhancing development and training of both PhD researchers and physician scientists. The
IGNITE KUH NRSA Training Core will address human health issues through increased education
and training of the next generation of researchers and physician scientists in basic research or
clinical science who can guide and lead future research programs aiming to lessen human
disease and suffering in KUH-specific fields.
Project Summary/Abstract Page 322
Contact PD/PI: Okusa, Mark D. NRSA-Training-001 (883)
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workforce: a mixed methods study. Blood Adv 2019;3:3550-61.
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issues of recruitment and retention. Blood Adv 2018;2:308.
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Recovery from Acute Kidney Injury. J Am Soc Nephrol 2016;27:3383-93.
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IFN-gamma. J Am Soc Nephrol 2016;28:1145-61.
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splenic cholinergic anti-inflammatory pathway. J Am Soc Nephrol 2013;24:1451-60.
24. Tanaka S, Inoue T, Hossack JA, Okusa MD. Nonpharmacological, Biomechanical Approaches to Control
Inflammation in Acute Kidney Injury. Nephron 2017;137:277-81.
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期刊论文(1)
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IGNITE KUH NRSA Training Core
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批准号:10457153
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资助金额:$38.75万
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Role of intracellular complement activation in kidney fibrosis
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资助金额:$24.23万
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Role of intracellular complement activation in kidney fibrosis
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资助金额:$12.63万
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