Multi-Disciplinary Training grant in Cancer Research
Multi-Disciplinary Training grant in Cancer Research
批准号:
10645134
负责人:
KAY F MACLEOD
金额:
$42.87万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1989
资助国家:
美国
项目状态:
已结题
起止时间:
1989-09-22 至 2024-06-30
中文摘要
节目概要
越来越多的新技术和学科被应用于翻译的挑战
将癌症研究的基本发现转化为有意义的临床结果。多学科
癌症研究培训补助金(MTCR)是一个既定的博士前培训计划,
由NIH/NCI T32-009594支持的芝加哥大学,旨在提供严格的
培训和相关经验的研究生谁将弥补下一代的
癌症研究的领导者和先驱。导弹技术管制制度的核心使命是培训我们最
有才华的博士预科生来解剖和设计新的方法来攻击癌症作为一种疾病,
无论是通过更好地理解
癌症的发生和发展,开发新的工具来监测和调节癌细胞
对治疗干预的反应,或利用有关人类癌症的更多信息,
数据集和新的计算方法,以确定最脆弱的癌症途径。
导弹技术管制制度领导层在2014年进行了一次战略审查,
方案目标,以现代化的培训提供给博士前癌症研究的学生在
芝加哥大学。通过更严格地挑选教员培训员和引进新的
癌症转化研究、化学生物学、分子生物学、
导弹技术控制制度(MTCR)计划提供的培训是多方面的,
学科和强调基于问题的学习和实践经验。导弹技术管制制度还
通过MyCHOICE计划和Polsky计划促进职业发展机会
芝加哥大学的创业与创新中心,我们的学员所在地
通过研讨会、讲习班和实习,接触到与职业相关的技能,
生物技术、科学新闻和其他研究密集型职业。我们还
制定了更有效的机制,从不同背景中招收学生
通过部署现有的学员和我们的校友网络,结合更多
招聘的整体规则。由于过去所有这些不同的程序变化,
周期,我们的计划已经显示出提高了生产力,减少了毕业时间,
培训成果,包括出版物、研究金和受训人员进入
研究密集型和研究相关的职业。在接下来的5年里,随着新的资金,
我们的目标是建立在我们成功的培训方法,最终目标是确保
下一代癌症研究人员拥有的知识、技能和工具,
对我们这个时代消除癌症死亡的集体目标产生有意义的影响。
英文摘要
Program Summary
Increasingly, new technologies and disciplines are being applied to challenges in translating
fundamental cancer research findings into meaningful clinical outcomes. The Multi-disciplinary
Training grant in Cancer Research (MTCR) is an established pre-doctoral training program at
the University of Chicago supported by NIH/NCI T32-009594 that seeks to provide rigorous
training and relevant experience to graduate students who will make up the next generation of
cancer research leaders and pioneers. The core mission of the MTCR is to train our most
talented pre-doctoral students to dissect and design new ways of attacking cancer as a disease,
whether that be through achieving a better understanding of the mechanistic underpinnings of
cancer initiation and progression, developing novel tools to monitor and modulate cancer cell
responses to therapeutic intervention, or to exploit increased information about human cancer
datasets and new computational methods to identify the most vulnerable cancer pathways.
MTCR leadership carried out a strategic review in 2014 resulting in a re-alignment of
programmatic goals to modernize training provided to pre-doctoral cancer research students at
UChicago. Through more stringent selection of faculty trainers and introduction of new
coursework and training elements in translational cancer research, chemical biology, molecular
engineering and computational approaches, the MTCR program provides training that is multi-
disciplinary and emphasizes problem-based learning and hands-on experience. The MTCR also
promotes career development opportunities through the MyCHOICE program and the Polsky
Center for Entrepreneurship & Innovation at the University of Chicago where our trainees are
exposed through seminars, workshops and internships to skills relevant to a career in
biotechnology, science journalism and other research-intensive careers. We have also
developed more effective mechanisms for recruitment of students from diverse backgrounds
through deployment of current trainees and our alumni network, in combination with more
holistic rubrics for recruitment. As a result of all these various program changes in the past
cycle, our program has shown enhanced productivity with reduced time to graduation, improved
training outcomes in terms of publications, fellowship awards and percent trainees going into
research-intensive and research-related careers. Over the next 5 years with renewed funding,
we aim to build on our successful training approaches, with the ultimate goal of ensuring that
the next generation of cancer researchers have the knowledge, skills and tools to make a
meaningful impact on the collective goal of eliminating cancer deaths in our time.
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Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1.
巨噬细胞中干扰素 γ 响应集落刺激因子 1,阻断有丝分裂信号的早期事件。
DOI:
--
发表时间:
1995
期刊:
Blood
影响因子:
20.3
作者:
[Xu,J, Kim,S, Chen,M, Rockow,S, Yi,SE, Wagner,AJ, Hay,N, Weichselbaum,RR, Li,W]
通讯作者:
Li,W
DOI:
10.2174/138945009788680392
发表时间:
2009-07
期刊:
Current drug targets
影响因子:
3.2
作者:
[Du W, Searle JS]
通讯作者:
Searle JS
DOI:
10.1371/journal.pone.0082220
发表时间:
2013
期刊:
PloS one
影响因子:
3.7
作者:
[Gorsic LK, Stark AL, Wheeler HE, Wong SS, Im HK, Dolan ME]
通讯作者:
Dolan ME
Rearrangement and expression of immunoglobulin genes in transgenic mice.
转基因小鼠中免疫球蛋白基因的重排和表达。
DOI:
10.1007/978-3-642-77633-5_16
发表时间:
1992
期刊:
Current topics in microbiology and immunology
影响因子:
--
作者:
[Storb,U, Engler,P, Klotz,E, Weng,A, Haasch,D, Pinkert,C, Doglio,L, Glymour,M, Brinster,R]
通讯作者:
Brinster,R
Actin dependent CD95 internalization is specific for Type I cells.
肌动蛋白依赖性 CD95 内化对 I 型细胞具有特异性。
DOI:
10.1016/s0014-5793(03)00558-1
发表时间:
2003
期刊:
FEBS letters
影响因子:
3.5
作者:
[Algeciras-Schimnich,Alicia, Peter,MarcusE]
通讯作者:
Peter,MarcusE
共 77 条
BNIP3 and BNIP3L (NIX) in lipid homeostasis and growth control in the liver
-
批准号:10752932
-
项目类别:
-
资助金额:$40.24万
-
财政年份:2016
-
负责人:KAY F MACLEOD
-
依托单位:
Autophagy in Tumor Progression and Metastasis
-
批准号:8311298
-
项目类别:
-
资助金额:$32.32万
-
财政年份:2012
-
负责人:KAY F MACLEOD
-
依托单位:
Autophagy in Tumor Progression and Metastasis
-
批准号:8874916
-
项目类别:
-
资助金额:$32.32万
-
财政年份:2012
-
负责人:KAY F MACLEOD
-
依托单位:
Autophagy in Tumor Progression and Metastasis
-
批准号:8680183
-
项目类别:
-
资助金额:$31.35万
-
财政年份:2012
-
负责人:KAY F MACLEOD
-
依托单位:
Autophagy in Tumor Progression and Metastasis
-
批准号:8529473
-
项目类别:
-
资助金额:$30.38万
-
财政年份:2012
-
负责人:KAY F MACLEOD
-
依托单位:
Autophagy in Tumor Progression and Metastasis
-
批准号:9097545
-
项目类别:
-
资助金额:$32.32万
-
财政年份:2012
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of BNIP3 in Mammary Tumorigenesis
-
批准号:8204507
-
项目类别:
-
资助金额:$30.58万
-
财政年份:2009
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of BNIP3 in Mammary Tumorigenesis
-
批准号:8010151
-
项目类别:
-
资助金额:$30.58万
-
财政年份:2009
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of BNIP3 in Mammary Tumorigenesis
-
批准号:7762187
-
项目类别:
-
资助金额:$31.52万
-
财政年份:2009
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of BNIP3 in Mammary Tumorigenesis
-
批准号:8408705
-
项目类别:
-
资助金额:$28.74万
-
财政年份:2009
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of BNIP3 in Mammary Tumorigenesis
-
批准号:7663515
-
项目类别:
-
资助金额:$31.52万
-
财政年份:2009
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of pRb in Stress Erythropoiesis
-
批准号:7391201
-
项目类别:
-
资助金额:$36.15万
-
财政年份:2005
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of pRb in Stress Erythropoiesis
-
批准号:7037455
-
项目类别:
-
资助金额:$37.23万
-
财政年份:2005
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of pRb in Stress Erythropoiesis
-
批准号:7215590
-
项目类别:
-
资助金额:$36.15万
-
财政年份:2005
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of pRb in Stress Erythropoiesis
-
批准号:6907908
-
项目类别:
-
资助金额:$38.13万
-
财政年份:2005
-
负责人:KAY F MACLEOD
-
依托单位:
Functions of pRb in Stress Erythropoiesis
-
批准号:7587993
-
项目类别:
-
资助金额:$36.15万
-
财政年份:2005
-
负责人:KAY F MACLEOD
-
依托单位:
Transgenic Mouse and Embryonic Stem Cell Facility
-
批准号:10379985
-
项目类别:
-
资助金额:$21.43万
-
财政年份:1997
-
负责人:KAY F MACLEOD
-
依托单位:
Transgenic Mouse and Embryonic Stem Cell Facility
-
批准号:10162521
-
项目类别:
-
资助金额:$21.55万
-
财政年份:1997
-
负责人:KAY F MACLEOD
-
依托单位:
Graduate Training Program in Cancer Biology - Renewal 01
-
批准号:8741191
-
项目类别:
-
资助金额:$35.71万
-
财政年份:1989
-
负责人:KAY F MACLEOD
-
依托单位:
Graduate Training Program in Cancer Biology - Renewal 01
-
批准号:9099777
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项目类别:
-
资助金额:$37.32万
-
财政年份:1989
-
负责人:KAY F MACLEOD
-
依托单位:
海外基金