Graduate Training Program in Cancer Biology - Renewal 01

芝加哥大学癌症生物学培训项目（CBTP）是一个多学科项目，其核心任务是培养癌症研究不同领域的研究生和博士后研究人员，包括但不限于癌症生物学的基本分子机制、系统方法、发育程序的重新激活和模式生物的使用、器官部位生物学、癌症治疗学和癌症群体遗传学。此外，我们的学员在假设建立和检验、科学努力的伦理、教学技能和对他们的工作如何为人类福祉和社会疾病管理做出贡献的理解方面打下坚实的基础。在过去5年的培训资助支持下，我们的癌症生物学项目已经牢固地确立了自己作为一个有效和充满活力的培训项目的地位，培训下一代癌症生物学家，以应对社会上癌症发病率不断上升所带来的卫生保健挑战。我们的43位教员培训师一直保持着杰出的出版记录，并获得了许多享有盛誉的荣誉。尽管资金环境具有挑战性，但与2008年相比，我们的教师在2013年增加了对他们研究的直接资助。强大的机构支持也使我们能够招募有才能的新教师，他们的专业知识为我们的学员增加了在令人兴奋的癌症生物学和科学新领域的研究机会。值得注意的是，我们继续收到越来越多的合格申请人来我们的项目。我们也很高兴地看到，我们的项目招募了大量代表性不足的少数族裔，而这些学员是我们最具活力的。在过去的5年里，我们对我们的项目进行了严格的评估，以进一步改进我们的课程，以适应这十年来癌症研究的变化。特别是，我们开发了课程的新方面，改变了对正式课程的要求，并为学员提供了个人发展机会。该项目也有了新的领导，Kay Macleod博士接替Geof Greene博士担任培训基金主任。与之前项目的所有领导层变动一样，由于麦克劳德博士在过去的5年里与格林博士密切合作，格林博士仍然是领导结构的一部分，因此项目的连续性得以保持。重要的是，麦克劳德博士带来了新的能量和想法，以保持项目的目的和目标导向的培训目标。总而言之，我们拥有专业的培训师团队和优秀的年轻学员团队，再加上不断完善的课程和培训环境，我们的项目在学员生产力和职业发展方面取得了巨大成功。鉴于我们项目的这些优势，以及我们持续招收更多合格、优秀的学员的能力，我们建议，在本次培训资助续期中，该项目需要并且值得保留博士预科(8)和博士后(3)的名额。

DESCRIPTION (provided by applicant): The Cancer Biology Training Program (CBTP) at the University of Chicago is a multi-disciplinary program whose core mission is to train graduate students and post-doctoral researchers in different areas of cancer research, including but not limited to fundamental molecular mechanisms in cancer biology, systems approaches, reactivation of developmental programs and use of model organisms, organ site biology, cancer therapeutics and cancer population genetics. In addition, our trainees receive robust grounding in hypothesis building and testing, the ethics of scientific endeavor, teaching skills and an understanding of how their work contributes to human well-being and disease management in society. Over the past 5 years of training grant support, our cancer biology program has firmly established itself as an effective and vibrant training program, training the next generation of cancer biologists needed to meet the health cares challenges arising from increasing cancer incidence in society. Our 43 faculty trainers have maintained an outstanding publication record and have been recognized by many prestigious honors. Despite a challenging funding climate, our faculty have increased direct funding of their research in 2013 compared to 2008. Strong institutional support has also allowed us to recruit talented new faculty whose expertise has increased the research opportunities for our trainees in exciting new areas of cancer biology and science. Significantly, we continue to receive an ever-increasing number of qualified applicants to our program. We are also pleased that we have been able to make significant increases in numbers of under-represented minorities recruited to our program, and these trainees are amongst our most dynamic. We have evaluated our program rigorously over the past 5 years to improve yet further our curriculum to meet the changing face of cancer research in this decade. In particular, we have developed new aspects of the curriculum, with altered demands in formal coursework, as well as introduced advances in personal development opportunities for trainees. The program has also come under new leadership with Dr. Kay Macleod taking over from Dr. Geof Greene as Director of this training grant. As with all previous leadership changes to the program, continuity remains thanks to Dr. Macleod having worked closely with Dr. Greene in the past 5 years and Dr. Greene remaining part of the leadership structure. Importantly, Dr. Macleod brings renewed energy and ideas to keep the program purposeful and goal-oriented in its training objectives. In summary, with our expert body of faculty trainers and talented group of young trainees, plus a constantly improving curriculum and training environment, our program has been highly successful in terms of trainee productivity and career outcomes. Given these strength of our program and our sustained ability to recruit increased numbers of qualified, outstanding trainees, we suggest that the program needs and merits retaining the number of pre-doctoral (8) and post-doctoral (3) slots in this training grant renewal.