Predoctoral Training in Pharmacological Sciences (Resubmission)

项目摘要/摘要 该博士前培训计划旨在提供广泛的药理学教育 获得博士学位。药理学培训计划(PSTP)的中心是 匹兹堡大学医学院药理学和化学生物学系 与分子药理学研究生项目(MPGP，也称为MPTP)，并包括 来自大学内三个学院和包括麻醉学、化学、 免疫学、医学、微生物学和分子遗传学、神经生物学、神经病学、耳鼻喉科、 药学和结构生物学。进入这个项目的研究生通常是第一个 被招募到跨学科生物医学研究生计划，在那里他们加入了一个计划， 包括生物医学科学、科学伦理和统计学以及研究轮换方面的核心教学教育。 该培训计划提供现代药理学基本要素方面的研究生课程 包括神经药理学、癌症药理学、心血管药理学、信号转导和 药物发现以及定量药代动力学、药效学和药物代谢的要素。 在主任和副主任的密切指导下，鼓励学生与精选的教职员工合作 他们致力于提供最好的环境来进行最高级别的严格研究 正直。包容的文化和对无数职业轨迹的支持是对实习生实验室的要求 现在需要在这些领域进行导师培训计划，职业探索课程也是如此 提供个性化的指导。学生从六个研究领域之一选择导师：癌症 药理学、细胞和器官系统药理学、药物发现、神经药理学、信号 转导和结构药理学。在完成综合考试和一个 论文提案，学生们全职从事研究，促进批判性思维，合作， 实验设计方面的共同指导和核心培训。因此，PSTP提供了一个当代和令人兴奋的 在严格和有教养的环境中为积极进取的学生提供培训机会，旨在创造 博士毕业生具有最高水平的技术和理论准备。

Project Summary/Abstract This Predoctoral Training Program is designed to provide a broad education in the Pharmacological Sciences leading to the Ph.D. degree. The Pharmacological Sciences Training Program (PSTP) is centered in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh School of Medicine and is closely associated with the Molecular Pharmacology Graduate Program (MPGP a.k.a. MPTP), and includes faculty from three schools within the University and ten departments including Anesthesiology, Chemistry, Immunology, Medicine, Microbiology and Molecular Genetics, Neurobiology, Neurology, Otolaryngology, Pharmaceutical Sciences, and Structural Biology. Graduate students entering this program are typically first recruited into the Interdisciplinary Biomedical Sciences Graduate Program where they join a program that includes core didactic education in biomedical sciences, scientific ethics and statistics and research rotations. The training program provides graduate coursework in the essential elements of modern pharmacology including neuropharmacology, cancer pharmacology, cardiovascular pharmacology, signal transduction and drug discovery and also elements of quantitative pharmacokinetics, pharmacodynamics and drug metabolism. With the close guidance of the director and vice-director, students are encouraged to work with a select faculty who are dedicated to providing the very best environments to conduct rigorous research of the highest integrity. A culture of inclusivity and support for myriad career tracks is a requirement for trainee laboratories and a mentor training program in these areas is now required as is a course in career exploration that also provides individualized coaching. Students choose mentors from one of six research areas: Cancer Pharmacology, Cell and Organ System Pharmacology, Drug Discovery, Neuropharmacology, Signal Transduction and Structural Pharmacology. Following completion of the comprehensive exam and a dissertation proposal, students are engaged full time in research that promotes critical thinking, collaboration, co-mentorship and core training in experimental design. The PSTP thus provides a contemporary and exciting training opportunity for motivated students within a rigorous and nurturing environment and aims to generate Ph.D. graduates of the highest level of technical and theoretical preparedness.