Biomedical Informatics, Bioinformatics and Cyberinfrastructure Enhancement Core

摘要/摘要 我们对个人和人口健康状况的了解，包括发展创新 疾病识别和治疗的方法，越来越多地建立在可获得和分析真实的 从提供常规护理的环境收集的世界数据(RWD)(例如，电子健康记录 (EHR)、索赔和账单活动)。当整合到临床研究数据仓库(CRW)时，RWD 成为支持临床研究/试验以及提供信息的医疗数据挖掘的关键来源 医疗保健在医学的各个方面。生物医学信息学、生物信息学和 网络基础设施增强核心(BiBEC)是加强和扩展所提供的工具和资源 针对拉美裔人口的真实世界数据，并开发培养熟练信息技术人员的计划。在……里面 此外，BiBEC致力于增加生物医学信息学、生物信息学和健康方面的知识 信息学，以便临床医生以及临床和翻译研究人员了解消费者所说的 了解它们在临床护理和研究环境中的应用。中环 这里提出的目标假设是，信息学工具和充分利用这些工具所需的资源 工具，可以在临床和转化性研究道路上的所有节点推进健康和医疗保健。这个 BiBEC的具体目标是：1)加强和扩展现有的健康数据基础设施，以改善临床 护理和最佳实践(电子健康记录/临床研究数据仓库)，2)增强可用性 波多黎各人和其他拉美裔人口进入临床和翻译行业的招聘机会 使用基于技术的创新的研究研究，以及3)为临床医生和临床和 这将使他们能够使用和应用现有的生物医学、生物信息学、 以及与健康信息学相关的数据和技术。BiBEC的创新包括：1)运营， 安全的临床研究数据仓库；2)积极支持临床推广的双语网站 试验机会，有一个面向社区的门户网站，个人可以在那里注册为临床志愿者 试验；3)符合FISMA和HIPAA的网上数据收集工具；以及4)培训和继续教育 在生物医学信息学、健康信息学和生物信息学中帮助临床医生和临床研究人员 了解生物医学和生物信息学信息和工具的消费者。

Abstract/Summary Our understanding of individual and population health status, including the development of innovative approaches to disease identification and treatment, is increasingly based on the availability and analyses of real- world data (RWD) collected from environments where routine care is provided (e.g., electronic health records (EHRs), claims and billing activities). When consolidated into clinical research data warehouses (CRDWs), RWD become a critical source for medical data mining supporting clinical research/trials, as well as informing healthcare in all facets of medicine. The goal of the Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement Core (BiBEC) is to strengthen and expand the tools and resources that supply real world data specific to Hispanic populations, and develop programs that prepare skilled informaticians. In addition, BiBEC is committed to increasing knowledge in biomedical informatics, bioinformatics, and health informatics so that clinicians as well as clinical and translational researchers are informed consumer of said services, understanding their applications in both clinical care and research environments. The central hypothesis of the aims presented here is that informatics tools, and the necessary resources to fully utilize these tools, can advance health and healthcare at all nodes along the clinical and translational research pathway. The specific aims of BiBEC are to: 1) strengthen and expand existing health data infrastructure to improve clinical care and best practices (electronic health records/clinical research data warehouse), 2) enhance the availability and recruitment opportunities of Puerto Rican and other Hispanic populations into clinical and translational research studies using technology-based innovations, and 3) develop training for clinicians and clinical and translational researchers which will enable their use and application of available biomedical, bioinformatic, and health informatics-related data and technologies. The innovation of BiBEC includes: 1) an operational, secure clinical research data warehouse; 2) bilingual website that proactively supports the promotion of clinical trial opportunities, with a community-facing web portal, where individuals may register as a volunteer in clinical trials; 3) FISMA and HIPAA-compliant web-based data collection tools; and 4) training and continuing education in biomedical informatics, health informatics, and bioinformatics that helps clinicians and clinical researchers be informed consumers of biomedical and bioinformatics information and tools.