Biomedical Informatics, Bioinformatics and Cyberinfrastructure Enhancement Core

生物医学信息学、生物信息学和网络基础设施增强核心

• 批准号: 10027575
• 负责人: Mary Helen Mays
• 金额: $ 20.78万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10027575
• 关键词: Acute; Bioinformatics; Caribbean region; Caring; Clinical; Clinical Data; Clinical Research; Clinical Trials; Communicable Diseases; Communities; Conduct Clinical Trials; Continuing Education; Data; Data Collection; Development; Disasters; Disease; Education; Effectiveness; Electronic Health Record; Emerging Communicable Diseases; Environment; Face; Goals; Health; Health Insurance Portability and Accountability Act; Health Personnel; Health Status; Healthcare; Hispanics; Hospitals; Individual; Informatics; Infrastructure; Institution; Knowledge; Language; Lead; Malignant Neoplasms; Maps; Medical; Medicine; Online Systems; Outcome; Participant; Pathway interactions; Population; Positioning Attribute; Public Health Informatics; Puerto Rican; Puerto Rico; Research; Research Personnel; Research Project Grants; Research Support; Resources; Rural Community; Secure; Services; Source; System; Technology; Training; Training Programs; Training and Education; Translational Research; Work; base; bilingualism; biomedical informatics; cardiometabolism; clinical care; clinical data warehouse; cyber infrastructure; data infrastructure; data mining; data warehouse; design; drug efficacy; electronic data; experimental study; field study; health care delivery; health data; improved; informatics tool; innovation; interdisciplinary approach; medically underserved; monitoring device; population health; programs; recruit; research study; routine care; support tools; tool; translational scientist; volunteer; web portal; web site

Abstract/Summary Our understanding of individual and population health status, including the development of innovative approaches to disease identification and treatment, is increasingly based on the availability and analyses of real- world data (RWD) collected from environments where routine care is provided (e.g., electronic health records (EHRs), claims and billing activities). When consolidated into clinical research data warehouses (CRDWs), RWD become a critical source for medical data mining supporting clinical research/trials, as well as informing healthcare in all facets of medicine. The goal of the Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement Core (BiBEC) is to strengthen and expand the tools and resources that supply real world data specific to Hispanic populations, and develop programs that prepare skilled informaticians. In addition, BiBEC is committed to increasing knowledge in biomedical informatics, bioinformatics, and health informatics so that clinicians as well as clinical and translational researchers are informed consumer of said services, understanding their applications in both clinical care and research environments. The central hypothesis of the aims presented here is that informatics tools, and the necessary resources to fully utilize these tools, can advance health and healthcare at all nodes along the clinical and translational research pathway. The specific aims of BiBEC are to: 1) strengthen and expand existing health data infrastructure to improve clinical care and best practices (electronic health records/clinical research data warehouse), 2) enhance the availability and recruitment opportunities of Puerto Rican and other Hispanic populations into clinical and translational research studies using technology-based innovations, and 3) develop training for clinicians and clinical and translational researchers which will enable their use and application of available biomedical, bioinformatic, and health informatics-related data and technologies. The innovation of BiBEC includes: 1) an operational, secure clinical research data warehouse; 2) bilingual website that proactively supports the promotion of clinical trial opportunities, with a community-facing web portal, where individuals may register as a volunteer in clinical trials; 3) FISMA and HIPAA-compliant web-based data collection tools; and 4) training and continuing education in biomedical informatics, health informatics, and bioinformatics that helps clinicians and clinical researchers be informed consumers of biomedical and bioinformatics information and tools.

摘要/概要 我们对个人和人口健康状况的了解，包括创新的发展， 疾病识别和治疗的方法越来越多地基于对真实的 从提供常规护理的环境收集的世界数据（RWD）（例如，电子健康记录 （EHR）、索赔和计费活动）。当整合到临床研究数据仓库（CRDW）中时，RWD 成为医疗数据挖掘的重要来源，支持临床研究/试验，并提供信息 医疗保健的各个方面。生物医学信息学、生物信息学和 网络基础设施增强核心（BiBEC）是加强和扩大提供的工具和资源 具体到西班牙裔人口的真实的世界数据，并开发程序，准备熟练的信息学家。在 此外，BiBEC致力于增加生物医学信息学、生物信息学和健康方面的知识 信息学，使得临床医生以及临床和转化研究人员被告知消费者所述 服务，了解其在临床护理和研究环境中的应用。中央 这里提出的目标假设是，信息学工具和充分利用这些工具的必要资源 工具，可以推进健康和医疗保健在所有节点沿着临床和转化研究途径。的 BiBEC的具体目标是：1）加强和扩大现有的健康数据基础设施，以改善临床 护理和最佳做法（电子健康记录/临床研究数据仓库），2）提高可用性 波多黎各人和其他西班牙裔人口进入临床和翻译的招聘机会 利用基于技术的创新进行研究，以及3）为临床医生和临床医生提供培训， 翻译研究人员，使他们能够使用和应用现有的生物医学，生物信息学， 和健康信息相关的数据和技术。BiBEC的创新包括：1）操作， 安全的临床研究数据仓库; 2）双语网站，积极支持临床研究的推广 试验机会，有一个面向社区的门户网站，个人可以在那里注册为临床试验的志愿者。 试验; 3）符合FISMA和HIPAA的基于网络的数据收集工具;以及4）培训和继续教育 在生物医学信息学，健康信息学和生物信息学，帮助临床医生和临床研究人员 向消费者提供生物医学和生物信息学信息和工具。