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Medical Scientist Training Program

医学科学家培训计划

基本信息

批准号：
10654680
负责人：
BARBARA I KAZMIERCZAK
金额：
$ 238.02万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10654680
关键词：
Medical Scientist Training Programs

项目摘要

PROJECT SUMMARY/ABSTRACT The Yale Medical Scientist Training Program proposes to train rigorous, visionary and resilient physician- scientists who are committed to improving the health of individuals and populations. Our mission is to provide students with integrated training in clinical medicine and research that qualifies them to perform at the highest standards as rigorous clinicians and scientists; to create a diverse and inclusive physician-scientist community to support and mentor trainees along axes of personal identity, clinical discipline and research domain; to cultivate the characteristics of curiosity, creativity, compassion and service in our trainees; and to develop skills associated with success in a broad range of physician-scientist research careers through experiential learning. The MSTP training plan integrates clinical and research training, allowing students to experience the integration of medicine and science that characterizes the physician-scientist career. Built upon the strong foundation of Yale School of Medicine and the departments, programs and faculty of Yale’s Graduate School of Arts and Sciences, School of Public Health, and School of Engineering and Applied Sciences, the MD-PhD program trains students in the responsible conduct of research across a diversity of disciplines and provides experiential training in the design, execution and presentation of rigorous and reproducible research. We are committed to increasing diversity of matriculated students along axes of race/ethnicity, geography, socioeconomic status and undergraduate institution. Intentional changes to our recruitment and holistic review processes have already increased the proportion of URiM students in our MD-PhD Program. Activities that build an inclusive MD-PhD community are embedded in School- and University-wide programs that support and promote trainees and faculty from groups underrepresented in medicine and science; these help to retain our students in dual-degree training. Our program prepares MD-PhD students for the challenges of a physician-scientist career, while opportunities to work with physician-scientists in medical and surgical disciplines in- and out-side of academia expose students to many careers that make use of the dual-degree. Our training plan proposes the following outcomes: 1) A continued increase in the diversity of our matriculants and graduates and ongoing commitment to training scholars in traditional and non-traditional PhD disciplines relevant to human health and disease. 2) Mentoring and training that allows 100% of our students to publish high-quality, rigorous, original work that reflects their skills and independence in research. 3) Provision of skills and motivation to support research-intensive physician-scientist careers, such that >85% of graduates engage in research during residency/fellowship training and >75% of their attempts to fund science are successful. And last, we aspire to match the success of Yale’s 1st 50 years of MD-PhD training by having >75% of our graduates remain engaged in research during their careers.

项目总结/摘要耶鲁大学医学科学家培训计划旨在培养严谨，有远见和有弹性的医生- 致力于改善个人和人群健康的科学家。我们的使命是学生在临床医学和研究的综合培训，使他们有资格表现在最高严格的临床医生和科学家的标准;创建一个多元化和包容性的医生-科学家社区支持和指导学员沿着轴的个人身份，临床学科和研究领域; 培养学员的好奇心、创造力、同情心和服务精神; 与通过体验式学习在广泛的医生科学家研究事业的成功。 MSTP培训计划整合了临床和研究培训，让学生体验医学和科学的融合，这是医生-科学家职业生涯的特点。建立在强者之上耶鲁大学医学院的基础和耶鲁大学研究生院的部门，项目和教师艺术与科学学院、公共卫生学院、工程与应用科学学院、MD-PhD 该计划培养学生在跨学科的多样性研究负责任的行为，并提供在设计，执行和严格的和可复制的研究演示体验培训。我们致力于增加入学学生的多样性沿着种族/民族，地理，社会经济地位和本科院校。有意改变我们的招聘和全面审查这些过程已经增加了我们的MD-PhD计划中URiM学生的比例。的活动建立一个包容性的MD-PhD社区嵌入到学校和大学范围内的计划，支持并促进来自医学和科学代表性不足的群体的学员和教师;这些有助于留住我们的学生在双学位培训。我们的计划准备MD-PhD学生的挑战，医生科学家的职业生涯，而机会与医生科学家在医疗和外科学术界内外的学科使学生接触到许多利用双学位的职业。我们的培训计划提出了以下成果：1）继续增加我们的多样性学生和毕业生，并持续致力于培养学者在传统和非传统博士学位与人类健康和疾病有关的学科。2)指导和培训，让我们的学生100%，发表高质量，严谨，原创的工作，反映他们的技能和研究的独立性。3)提供支持研究密集型医生-科学家职业的技能和动力，例如>85%的毕业生在住院医师/奖学金培训期间从事研究，他们资助科学的尝试中有75%以上是成功最后，我们希望通过以下方式与耶鲁大学第一个50年的MD-PhD培训相匹配 >75%的毕业生在其职业生涯中继续从事研究。

项目成果

期刊论文数量（83）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Exome Sequencing as a Potential Diagnostic Adjunct in Sporadic Congenital Hydrocephalus.

外显子组测序作为散发性先天性脑积水的潜在诊断辅助手段。

DOI：
10.1001/jamapediatrics.2020.4878
发表时间：
2021
期刊：
JAMA pediatrics
影响因子：
26.1
作者：
Sullivan,William;Reeves,BenjaminC;Duy,PhanQ;Nelson-Williams,Carol;Dong,Weilai;Jin,ShengChih;Kahle,KristopherT
通讯作者：
Kahle,KristopherT

Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy.

DOI：
10.1161/circulationaha.121.056265
发表时间：
2022-04-19
期刊：
CIRCULATION
影响因子：
37.8
作者：
Riaz, Muhammad;Park, Jinkyu;Sewanan, Lorenzo R.;Ren, Yongming;Schwan, Jonas;Das, Subhash K.;Pomianowski, Pawel T.;Huang, Yan;Ellis, Matthew W.;Luo, Jiesi;Liu, Juli;Song, Loujin;Chen, I-Ping;Qiu, Caihong;Yazawa, Masayuki;Tellides, George;Hwa, John;Young, Lawrence H.;Yang, Lei;Marboe, Charles C.;Jacoby, Daniel L.;Campbell, Stuart G.;Qyang, Yibing
通讯作者：
Qyang, Yibing

Multimodal analysis suggests differential immuno-metabolic crosstalk in lung squamous cell carcinoma and adenocarcinoma.