Medical Scientist Training Program

医学科学家培训计划

基本信息

批准号：
10654680
负责人：
BARBARA I KAZMIERCZAK
金额：
$ 238.02万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10654680
关键词：
Medical Scientist Training Programs

项目摘要

PROJECT SUMMARY/ABSTRACT The Yale Medical Scientist Training Program proposes to train rigorous, visionary and resilient physician- scientists who are committed to improving the health of individuals and populations. Our mission is to provide students with integrated training in clinical medicine and research that qualifies them to perform at the highest standards as rigorous clinicians and scientists; to create a diverse and inclusive physician-scientist community to support and mentor trainees along axes of personal identity, clinical discipline and research domain; to cultivate the characteristics of curiosity, creativity, compassion and service in our trainees; and to develop skills associated with success in a broad range of physician-scientist research careers through experiential learning. The MSTP training plan integrates clinical and research training, allowing students to experience the integration of medicine and science that characterizes the physician-scientist career. Built upon the strong foundation of Yale School of Medicine and the departments, programs and faculty of Yale’s Graduate School of Arts and Sciences, School of Public Health, and School of Engineering and Applied Sciences, the MD-PhD program trains students in the responsible conduct of research across a diversity of disciplines and provides experiential training in the design, execution and presentation of rigorous and reproducible research. We are committed to increasing diversity of matriculated students along axes of race/ethnicity, geography, socioeconomic status and undergraduate institution. Intentional changes to our recruitment and holistic review processes have already increased the proportion of URiM students in our MD-PhD Program. Activities that build an inclusive MD-PhD community are embedded in School- and University-wide programs that support and promote trainees and faculty from groups underrepresented in medicine and science; these help to retain our students in dual-degree training. Our program prepares MD-PhD students for the challenges of a physician-scientist career, while opportunities to work with physician-scientists in medical and surgical disciplines in- and out-side of academia expose students to many careers that make use of the dual-degree. Our training plan proposes the following outcomes: 1) A continued increase in the diversity of our matriculants and graduates and ongoing commitment to training scholars in traditional and non-traditional PhD disciplines relevant to human health and disease. 2) Mentoring and training that allows 100% of our students to publish high-quality, rigorous, original work that reflects their skills and independence in research. 3) Provision of skills and motivation to support research-intensive physician-scientist careers, such that >85% of graduates engage in research during residency/fellowship training and >75% of their attempts to fund science are successful. And last, we aspire to match the success of Yale’s 1st 50 years of MD-PhD training by having >75% of our graduates remain engaged in research during their careers.

项目摘要/摘要耶鲁大学医学科学家培训计划提案，以培训严格，有远见和有韧性的医生 - 致力于改善个人和人口健康的科学家。我们的使命是提供接受临床医学和研究综合培训的学生，使他们有资格表现最高严格的临床医生和科学家的标准；建立一个多样化和包容性的身体科学家社区沿着个人身份，临床学科和研究领域的轴心支持和心理学生；在我们的培训中培养好奇心，创造力，同情和服务的特征；并发展技能通过经验丰富的学习，与广泛的身体科学家研究事业的成功相关。 MSTP培训计划整合了临床和研究培训，使学生可以体验医学和科学的整合是身体科学家职业的特征。建立在强大的基础上耶鲁大学医学院以及耶鲁大学研究生院的系，课程和教职员工的基金会艺术与科学，公共卫生学院以及工程与应用科学学院，MD-PHD 计划培训学生在各种各样的学科中负责任的研究，并提供严格和可重复研究的设计，执行和表现方面的经验培训。我们致力于沿着种族/种族，地理，地理，社会经济地位和本科机构。有意改变我们的招聘和整体审查流程已经增加了我们的MD-PHD计划中URIM学生的比例。活动建立一个包容性的MD-PHD社区已嵌入学校和大学范围的计划中，以支持从医学和科学领域人数不足的团体中促进学员和教师；这些有助于保留我们的学生接受双度培训。我们的计划为MD-PHD学生做好了准备的挑战身体科学家的职业，同时与医学和外科医师的身体科学家合作的机会学术界和外部学科的学科使学生接触了许多利用双学位的职业。我们的培训计划提出以下结果：1）我们的多样性持续增加族裔和毕业生以及对培训传统和非传统博士学位学者的持续承诺与人类健康和疾病有关的学科。 2）指导和培训使我们的100％的学生得以发表高质量，严格的原创作品，反映了他们的研究技能和独立性。 3）提供支持研究密集型身体科学家职业的技能和动力，使毕业生中有85％在居住/奖学金培训期间进行研究，> 75％的资助科学尝试是成功的。最后，我们渴望通过拥有 > 75％的毕业生在职业生涯中仍在从事研究。

项目成果

期刊论文数量（83）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Exome Sequencing as a Potential Diagnostic Adjunct in Sporadic Congenital Hydrocephalus.

外显子组测序作为散发性先天性脑积水的潜在诊断辅助手段。

DOI：
10.1001/jamapediatrics.2020.4878
发表时间：
2021
期刊：
JAMA pediatrics
影响因子：
26.1
作者：
Sullivan,William;Reeves,BenjaminC;Duy,PhanQ;Nelson-Williams,Carol;Dong,Weilai;Jin,ShengChih;Kahle,KristopherT
通讯作者：
Kahle,KristopherT

Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy.

DOI：
10.1161/circulationaha.121.056265
发表时间：
2022-04-19
期刊：
CIRCULATION
影响因子：
37.8
作者：
Riaz, Muhammad;Park, Jinkyu;Sewanan, Lorenzo R.;Ren, Yongming;Schwan, Jonas;Das, Subhash K.;Pomianowski, Pawel T.;Huang, Yan;Ellis, Matthew W.;Luo, Jiesi;Liu, Juli;Song, Loujin;Chen, I-Ping;Qiu, Caihong;Yazawa, Masayuki;Tellides, George;Hwa, John;Young, Lawrence H.;Yang, Lei;Marboe, Charles C.;Jacoby, Daniel L.;Campbell, Stuart G.;Qyang, Yibing
通讯作者：
Qyang, Yibing

Targeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides.