Portable Ankle Robotics to Reverse Foot Drop After Stroke.

便携式踝关节机器人可逆转中风后足下垂的情况。

• 批准号: 10657017
• 负责人: Bradley Hennessie
• 金额: $ 6.67万
• 依托单位: NEXTSTEP ROBOTICS, LLC
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10657017
• 关键词: Address; Ankle; Biomechanics; Blinded; COVID-19 pandemic; Caring; Clinical; Clinical Research; Contracts; Devices; Foot-drop; Gait; Impairment; Joints; Mediating; Participant; Patients; Phase; Physical therapy; Randomized Clinical Trials; Robot; Robotics; Safety; Site; Testing; Therapeutic; Training; Walking; clinical efficacy; design; environmental change; experience; instrument; light weight; locomotor tasks; motor learning; portability; post stroke; product development; prototype; recruit; robot exoskeleton; usability; wireless

Overall Project Summary This proposal finalizes the design of a portable ankle robot as a therapeutic device to reverse foot drop and restore safe independent walking after stroke, then conducts a rigorous randomized clinical trial to establish clinical efficacy for this new market application. Product development is inspired by our five positive clinical studies that demonstrate that ankle robot-mediated functional motor learning is most effectively conducted in the context of locomotor task-oriented training. In Phase I, we pursued finalization of a lighter weight, battery powered, and wirelessly controlled ankle robot (AMBLE) that meets basic clinical usability standards for regular mobility-focused physical therapy (PT). Specific Phase I accomplishments include designing and bench testing a functional beta prototype that meets key safety, stability, and comfort metrics during over-ground walking and mobility tasks for full integration into PT. Phase II (3-yrs) is a blinded, randomized clinical trial investigating the hypothesis that 9 weeks (18 sessions) of PTR is more effective than PT alone to reverse foot drop as assessed by instrumented gait biomechanics and blinded clinician assessment. Our results will establish safety and initial efficacy for reversal of foot drop as a new market application filling an unmet need, and shift care toward PT-integrated robotic exoskeletons across other impaired joints.

整体项目总结