Investigator Development Core

研究者开发核心

• 批准号: 10656511
• 负责人: Donna D Spruijt-Metz
• 金额: $ 86.38万
• 依托单位: CHILDREN'S HOSPITAL OF LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10656511
• 关键词: Address; Adoption; Affect; Award; California; Child; Chronic; Chronic Disease; Clinical; Clinical Sciences; Collaborations; Communities; Data; Data Analyses; Development; Diet; Discipline; Disparity; Dissemination and Implementation; Dyslipidemias; Elderly; Ensure; Ethnic Origin; Evaluation; Faculty; Family; Feedback; Fostering; Funding; Funding Mechanisms; Goals; Government; Grant; Growth; Health Professional; Institution; Latino; Latino Population; Leadership; Letters; Life Experience; Link; Mentors; Methods; Monitor; National Institute on Minority Health and Health Disparities; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Outcome; Pilot Projects; Play; Process; Publications; Race; Research; Research Personnel; Research Support; Resources; Role; Science; Series; Support System; Talents; Training; Training Programs; Translational Research; Underrepresented Populations; United States National Institutes of Health; Universities; Update; Writing; career; career development; community engagement; community organizations; data management; experience; health disparity; innovation; meetings; member; multidisciplinary; non-alcoholic fatty liver disease; prevent; programs; research and development; satisfaction; success; translational approach; translational engagement; translational impact; voucher

The Investigator Development Core (IDC) of the Southern California Center for Chronic Health Disparities in Latino Families and Children (SCC-CHDLFC) will play a central role in developing new rigorous, translational, and community-engaged science, and supporting the growth and impact of the Center. The IDC will support new research that addresses the disparities in co-occurring chronic diseases affecting Latinos in Southern California, including obesity, type 2 diabetes, non-alcoholic fatty liver disease and dyslipidemia, and that is led by investigators who are early-career, new to the field, or from underrepresented populations. We will promote and prioritize support for projects incorporating transdisciplinary and community-engaged team science. Two funding mechanisms will support this effort across the region: 1) Pilot grants, awarded competitively to seven projects each year ($50,000/project); and 2) Vouchers to supplement existing projects from early-stage investigators via support from Center or other Institutional Research Cores ($50,000/year for vouchers up to $10,000 each). In addition, the Core will create a mentoring network, that will match pilot study investigators with more established investigators based on an initial pool of 41 multi-disciplinary researchers who are focused on disparity research across Southern California. The IDC leadership builds on a long-term collaboration between the co-Directors (Drs. de la Haye and Spruijt-Metz at USC), expertise in leadership of similar career development cores (Dr. Elder at SDSU), and experience overseeing research development at the Southern California Clinical and Translational Science Institute (Dr. de la Haye). Specific Aim 1 will build and support a pool of diverse research teams to be successful in submitting and obtaining pilot project funding. We will support transdisciplinary team science from the initial stages of project development through project launch and evaluation. We will leverage the Center’s cores and other institutional resources to engage diverse researchers, requesting pre-submission Letters of Intent (LOIs) for initial project review. Selected LOIs will be linked to mentors and with pre-award support to increase their potential for success, adoption of transdisciplinary team science principles as well as expertise from the center’s Methods and Data Sub-Core. A multi-disciplinary, community-engaged review process will ensure funding of innovative and translational science. Specific Aim 2 will support pilot-funded teams to achieve their research goals by providing multidisciplinary mentoring, networking, and training. Research success and impact will be supported via regular meetings with matched mentors, training and support on project launch and management, team science, research translation and community engagement, a seminar series, and an Annual Research Showcase featuring pilot project updates. Specific Aim 3 will evaluate pilot project outcomes and IDC activities using mixed methods approaches to track pilot project outcomes based on research and career development, and ultimately the creation of a diverse pool of new investigators focused on understanding, preventing and treating multiple chronic diseases among Latinos across Southern California.

南加州慢性健康差异中心研究者发展中心（IDC） 在拉丁美洲家庭和儿童（SCC-CHDLFC）将发挥核心作用，在发展新的严格，翻译， 和社区参与的科学，并支持该中心的增长和影响。IDC将支持新的 研究解决了影响南加州拉丁美洲人的共同发生的慢性疾病的差异， 包括肥胖、2型糖尿病、非酒精性脂肪肝和血脂异常， 研究人员是早期职业，新的领域，或来自代表性不足的人群。我们将促进和 优先支持包含跨学科和社区参与的团队科学的项目。两个供资 将通过以下机制支持整个区域的这一努力：1）试点赠款，以竞争方式授予七个项目 每年（每个项目50 000美元）; 2）由早期调查员补充现有项目的调查员， 来自中心或其他机构研究核心的支持（50，000美元/年，每张代金券最高10，000美元）。在 此外，核心小组还将建立一个指导网络，将试点研究的调查人员与更成熟的 研究人员基于41名专注于差异研究的多学科研究人员的初始池 横跨南加州。IDC领导层建立在共同主任之间的长期合作基础上 (Drs. de la Haye和南加州大学的Spruijt-Metz），在类似职业发展核心领导方面的专业知识（Elder博士 在SDSU），并有监督南加州临床研究开发的经验， 翻译科学研究所（德拉哈耶博士）。具体目标1将建立和支持一个多样化的研究池 团队成功提交并获得试点项目资金。我们将支持跨学科团队 从项目开发的初始阶段到项目启动和评估，科学。我们将利用 该中心的核心和其他机构资源，以吸引不同的研究人员，要求预先提交 意向书（LOI），用于初步项目审查。选定的意向书将与导师联系起来， 支持提高他们的成功潜力，采用跨学科团队科学原则，以及 该中心的方法和数据子核心的专业知识。多学科、社区参与的审查 这一进程将确保为创新和转化科学提供资金。具体目标2将支持试点资助的团队 通过提供多学科指导，网络和培训来实现他们的研究目标。研究 将通过定期与配对导师举行会议、培训和项目支持， 启动和管理，团队科学，研究翻译和社区参与，系列研讨会， 以及年度研究展示，展示试点项目的最新情况。具体目标3将评估试点项目 利用混合方法跟踪试验项目成果， 和职业发展，并最终创建一个多元化的新调查人员库，重点关注 了解、预防和治疗南加州拉美裔人的多种慢性病。