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中文摘要
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项目总结/摘要 这是一份K12补助金的续期申请,以继续支持布法罗口腔研究和专业 培训(BORST)计划,一个综合研究培训计划,总部设在牙科医学院, 布法罗大学(UB)。BORST的总体目标是促进牙科的发展, 专家-科学家学者专注于口腔、牙科和颅面研究。为了实现这一目标,BORST 提供指导,跨学科的研究培训机会,在口腔健康,颅面生物学, 生物工程BORST提供了一个强大的课程和专题研究经验,在一个综合的 框架,强调指导,科学进步,学术生涯的发展,granitarian, 和生产力。此K12应用程序要求支持牙医参与临床专业培训, 博士研究培训牙医科学家在基础,转化或生物工程科学重要, 牙齿、口腔或颅面健康。BORST是牙科医学院的一个组成部分, 医学院其他学科和部门的教师和学员/学者, 生物工程学在UB指导和职业发展活动按主题分为5个战略 研究重点领域:(i)免疫学和先天防御,(ii)口腔病原体与全身性疾病的关系 疾病,(iii)唾液和唾液腺,(iv)口腔生物的微生物发病机制,以及(v)骨和 结缔组织/组织工程。BORST受益于出色和经过时间考验的行政管理 支持系统和机构的承诺,将提供持续的支持,以口头部 生物学BORST计划将支持两名博士后学者每年的奖项谁将从事 在这个综合职业发展计划中。BORST计划的目标是提供早期职业生涯 为有才华的牙医谁希望追求研究和学术生涯的牙科专家的发展 有博士学位将使用一个综合的多年评估计划来衡量BORST目标 和目标得到满足。由此产生的学者将做好充分准备,从事有意义的基本和/或 口腔健康的转化研究。
英文摘要
PROJECT SUMMARY / ABSTRACT This is a renewal application for a K12 grant to continue support for the Buffalo Oral-Research and Specialty Training (BORST) Program, an integrated research training program based in the School of Dental Medicine at the University at Buffalo (UB). The overarching objective of BORST is to foster the development of dental specialist-scientist scholars focused on oral, dental and craniofacial research. To accomplish this goal, BORST offers mentored, interdisciplinary research training opportunities in oral health, craniofacial biology and bioengineering. BORST provides a strong curriculum and thematic research experiences in an integrative framework that emphasizes mentoring, scientific advancement, academic career development, grantsmanship, and productivity. This K12 application requests support for dentists to engage in clinical specialty training and PhD research training for dentist-scientists in basic, translational or bioengineering sciences important to dental, oral or craniofacial health. BORST is an integral part of the School of Dental Medicine that engages faculty and trainees/scholars in other disciplines and departments in the School of Medicine and Bioengineering at UB. Mentoring and career development activities are thematically grouped into 5 strategic areas of research focus: (i) immunology and innate defenses, (ii) relationship of oral pathogens to systemic disease, (iii) saliva and salivary glands, (iv) microbial pathogenesis of oral organisms, and (v) bone and connective tissues/tissue engineering. BORST benefits from outstanding and time-tested administrative support systems and institutional commitment that will provide continued support to the Department of Oral Biology. The BORST Program will support two postdoctoral scholars each year of the award who will engage in this combined career development program. The goal for the BORST Program is to provide early career development for talented dentists who wish to pursue research and academic careers as dental specialists with a PhD. An integrated, multi-year evaluation plan will be used to measure the extent to which BORST goals and objectives are met. The resulting scholars will be well prepared to engage in meaningful basic and/or translational oral health research.
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Traumatic Events and Injury: Etiologic Mechanisms for Temporomandibular Disorders
Immunometabolic Regulation of MDSCs in Periodontitis
Immunometabolic Regulation of MDSCs in Periodontitis
Post-Transcriptional Control of Aging-Associated Inflammation and Bone Homeostasis
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