Research Education Component

摘要 阿尔茨海默病及相关疾病的病因、表现及防治研究 痴呆症(ADRD)越来越需要包括临床医生在内的基于团队的多学科方法， 临床和基础科学研究人员。华盛顿大学阿尔茨海默氏症的目标 研究中心研究教育部分(UW ADRC REC)是为促进发展而蓬勃发展的， 创新和多样化的ADRD研究社区，能够定义不同的生物学和机制 ADRD的驱动程序。UW ADRC REC将首先为REC学员提供一年的基础广泛的课程， 包括基础、翻译和临床研究实习生，以建立对 ADRD的临床表现是在临床上遇到的，在实验室中研究过。支持 在培训课程和UW ADRC会议上广泛使用电话会议将提供 这种动态的临床和研究环境为ADRD研究人员提供了一个研究美国老龄化和ADRD的环境 原住民社区和人口。UW ADRC REC将第二次为REC调查人员提供支持 UW ADRC新手或首次进入ADRD研究领域的访问和互动 UW ADRC生态系统中提供的大量专业知识、数据和资源。这一支持是 明确的目标是包括年轻的研究人员，他们正在开发的研究计划将形成 未来利用UW ADRC产生的资源和数据进行研究。最后，UW ADRC REC将 寻求填补在使用可公开获得的与反兴奋剂相关的“大数据”方面的培训和专门知识方面的严重空白 在整个国家ADRD研究界。通过与总部位于西雅图的Sage合作 Bionnetworks，它将建立和支持为期两天的年度ADRD开放式神经科学研讨会，该研讨会将 帮助以ADRD为重点的受训人员和研究人员熟练掌握公开可用的数据集及其来源 和结构，它们的用户界面，以及它们的使用的统计和计算方法。这些 研讨会将向UW ADRC和全国其他ADRC的个人开放。通过持续 协作圣人生物网络，它将进一步支持种子和支持导师开放 神经科学工作组专注于基于这些数据开发新的研究项目。这将是 包括逐步使用综合临床、神经心理测量、成像和生物标记物、遗传学和 在这些ADRD开放式神经科学研讨会上，UW ADRC生成了整个ADRC的病理数据。

Abstract Research into the causes, presentation, prevention and treatment of Alzheimer's disease and related dementias (ADRD) increasingly demands a team-based multi-disciplinary approach that includes clinicians, clinical and basic science researchers. The goal of the University of Washington Alzheimer's Disease Research Center Research Education Component (UW ADRC REC) is to foster the development of a thriving, innovative and diverse ADRD research community that is able to define the varied biological and mechanistic drivers of ADRD. The UW ADRC REC will first provide a one year broad-based curriculum to REC Trainees, including basic, translational and clinical research trainees, in order to establish a common understanding of the clinical presentation of ADRD as they are ere encountered in the clinic and studied in the lab. Support for the widespread use of teleconferencing at training sessions and UW ADRC meetings will provide access to this dynamic clinical and research environment to ADRD investigators studying aging and ADRD in American Native communities and populations. The UW ADRC REC will second provide support to REC Investigators new to the UW ADRC or entering the ADRD research field for the first time in accessing and interacting with the vast array of expertise, data and resources available within the UW ADRC ecosystem. This support is explicitly targeted to include young investigators whose developing research programs will form the pipeline for research utilizing resources and data generated by the UW ADRC in the future. Last, the UW ADRC REC will seek to fill a critical gap in training and expertise in the use of publicly available ADRD-related `big data' throughout the national ADRD research community. Through its partnership with Seattle-based Sage Bionetworks, it will establish and support an annual two-day ADRD Open Neuroscience Workshop that will help ADRD-focused trainees and investigators develop proficiency with publicly-available datasets, their origins and structures, their user interfaces, and statistical and computational approaches to their use. These workshops will be open to individuals at the UW ADRC and other ADRCs nationally. Through ongoing collaborations Sage Bionetworks, it will further support the seeding and support of mentored Open Neuroscience working groups focused on developing new research projects based on these data. This will include the progressive use of integrated clinical, neuropsychometric, imaging and biomarker, genetic and pathological data generated throughout the UW ADRC in these ADRD Open Neuroscience Workshops.