Core NIBS

神经成像和生物统计学(NIBS)核心将为合成和集成提供技术支持 跨英才研究中心的神经成像和统计方法和分析 补充和综合卫生(CERCIH)项目。我们提出的三个项目旨在评估 自上而下和自下而上的心身联合疗法如何提高偏头痛的神经生理反应 病人。通过提供通用的图像采集和分析框架，NIBS核心将促进 能够执行项目内和项目间分析以及更大规模的分析，这些分析不仅将 CERCIH和NCCIH资助的其他相关研究，从而使我们能够解决 关于慢性疼痛条件下心身疗法的神经生物学的更广泛的问题，从而 根据我们的数据共享计划，增加此类数据对更广泛社区的价值。 NIBS核心的目标将是优化和整合整个CERCIH的神经成像方法 项目将涵盖超高场(7T)结构和功能磁共振成像、正电子发射断层扫描 (PET)、质子磁共振波谱(H-MRS)和心率变异性(HRV)/功能磁共振联合检查 扫描中央自治网络(CAN)的评估。AIMS还将提供统一的、 全面的数据分析和生物统计学/神经解剖学支持，组织统一的数据库和 数据共享基础设施，并支持对这三家公司收集的组合数据集进行探索性分析 项目。

The Neuroimaging and Biostatistics (NIBS) Core will provide technical support to synthesize and integrate neuroimaging and statistical methods and analyses across the Center of Excellence for Research on Complementary and Integrative Health (CERCIH) Projects. The three Projects we propose aim to evaluate how combined top-down and bottom-up mind-body therapies boost neurophysiological response in migraine patients. By providing a common image acquisition and analysis framework, the NIBS Core will facilitate the ability to perform intra- and inter-project analyses as well as larger-scale analyses that integrate not only the CERCIH but other related NCCIH-funded studies at the institution, thus allowing us to address on a still broader scale questions about the neurobiology of mind-body therapies in chronic pain conditions, and thereby increase the value of such data to the broader community when shared according to our Data Sharing Plan. The Aims of the NIBS Core will be to optimize and integrate neuroimaging methods across the CERCIH Projects, which will cover ultrahigh field (7T) structural and functional MRI, positron emission tomography (PET), proton magnetic resonance spectroscopy (H-MRS), and combined heart rate variability (HRV) / fMRI scanning for assessment of the Central Autonomic Network (CAN). Aims will also provide unified, comprehensive data analysis and biostatistical / neuroanatomical support, organize a unified database and data-sharing infrastructure, and support exploratory analyses on combined datasets collected by all three Projects.