Core A: Administrative Core

核心A：行政核心 摘要 行政核心旨在协调和支持该方案的所有活动。它 我将积极主动地工作，以确保整个研究项目和核心的完整整合 围绕“整合基因组学”这一主题，这是该计划的重点。芯会 负责监督本计划的日常活动，并确保 方案的目标已经实现。除其他活动外，该核心将每两周组织一次 整个研究团队的会议，协调科学研讨会和讲习班，并举行一个 年度撤退我们成立了一个由专家组成的外部咨询委员会 来自南加州大学以外的统计遗传学，癌症遗传流行病学，整合基因组学， 生物信息学和高性能计算。我们还组织了一个内部咨询小组， 委员会（IAC）利用我们在这些相同学科的同事的深厚专业知识 在USC。该核心将协调东非共同体的年度会议和 它将促进与EAC或IAC成员全年的额外互动 根据需要核心将协调旅行、采购用品、监督预算、处理 人事问题，提交年度进展报告，并协助征聘新的调查员， 博士后和学生 作为该核心的联合主任，Gauderman博士和Siegmund博士将共同承担以下责任： 项目的所有组织和财务活动。此外，高德曼博士将假设 项目活动的具体领导和Siegmund博士核心活动的具体领导。 这些特定于项目和核心的角色将保证整体 该计划得到了充分的管理。他们还将建立所需的基础设施 在项目和核心之间进行有效的沟通和协作。他们将共同主持 我们的IAC和计划一个EAC的年度会议以及一个单独的年度科学务虚会 所有项目和核心调查员利用他们作为司长的经验 生物统计学（Gauderman博士）兼生物统计学和流行病学教育主任 计划（博士Siegmund），他们将确保这一计划的雄心勃勃的目标是完全 协调和支持。

Core A: Administrative Core Abstract The administrative core is designed to coordinate and support all the activities of this Program. It will work pro-actively to assure complete integrations across the Research Projects and Cores around the theme of “integrative genomics” that is the focus of the program. The Core will be responsible for overseeing the day-to-day activities of this program and assuring that the overall goals of the program are achieved. Among other activities, this Core will organize biweekly meetings of the entire research team, coordinate scientific seminars and workshops, and hold an annual retreat. We have assembled an External Advisory Committee (EAC) comprising experts from outside USC in statistical genetics, cancer genetic epidemiology, integrative genomics, bioinformatics, and high-performance computing. We have also assembled an Internal Advisory Committee (IAC) drawing on the deep expertise of our colleagues across these same disciplines within USC. The Core will coordinate an annual meeting of the EAC and quarterly meetings of the IAC, and it will facilitate additional interactions with EAC or IAC members throughout the year as needed. The Core will coordinate travel, purchase supplies, monitor budgets, handle personnel issues, submit annual progress reports, and facilitate recruitment of new investigators, post docs, and students. As co-directors of this core, Drs. Gauderman and Siegmund will jointly assume responsibility for all organizational and financial activities of the project. In addition, Dr. Gauderman will assume specific leadership of Project activities and Dr. Siegmund specific leadership of Core activities. These Project- and Core-specific roles will guarantee that both important elements of the overall program are being adequately administered. They will also establish the infrastructure needed for effective communications and collaboration across the Projects and Cores. They will co-chair our IAC and plan one annual meeting of the EAC as well as a separate annual scientific retreat with all program and core investigators. Leveraging their experience as Director of the Division of Biostatistics (Dr. Gauderman) and Director of our Biostatistics and Epidemiology Education Program (Dr. Siegmund), they will assure that the ambitious goals of this program are fully coordinated and supported.