CAREER-ENHANCEMENT

职业提升

• 批准号: 10707053
• 负责人: Sandesh Chakravarthy Sreenath Nagamani
• 金额: $ 7.2万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-06 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10707053
• 关键词: Affect; American; Award; Bone Diseases; Clinical; Clinical Investigator; Clinical Research; Clinical and Translational Science Awards; Community Outreach; Complement; Data; Dentists; Diagnosis; Disease; Education and Outreach; Educational Status; Ensure; Faculty; Family; Fellowship; Foundations; Funding; Goals; Grant; Health Personnel; Health Professional; Individual; Institution; Intellectual and Developmental Disabilities Research Centers; Laboratories; Laboratory Finding; Longitudinal Studies; Medical; Medical Education; Medical Students; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Minerals; Mission; Osteogenesis Imperfecta; Osteoporosis; Pathway interactions; Patient Education; Patients; Physicians; Postdoctoral Fellow; Primary Health Care; Process; Professional Organizations; Publications; Publishing; Qualifying; Rare Diseases; Research; Research Personnel; Research Project Grants; Research Training; Resources; Role; Scientist; Site; Societies; Talents; Testing; Time; Training; Training Activity; Training and Education; Translating; Translational Research; Travel; United States National Institutes of Health; Work; bone; career; clinical practice; design; experimental study; genetic counselor; graduate school; improved; industry partner; interest; medical schools; meetings; next generation; novel marker; novel therapeutics; outreach; outreach program; patient advocacy group; patient engagement; patient oriented; pre-doctoral; professional partner; programs; recruit; skeletal disorder; skill acquisition; skills; success; symposium; targeted treatment; translational scientist

PROJECT SUMMARY (Career Enhancement Core) A key goal of the Rare Disease Clinical Research Network (RDCRN) is to train the next-generation of rare disease clinical/translational investigators. The Brittle Bone Disorders Consortium (BBDC) has made significant progress towards contributing to this mission. Over the past five years, the BBDC provided Geisman research fellowship funding to seven highly-qualified early-stage investigators (out of a total of 14 funded by the OIF). Additionally, by leveraging Institutional resources, the BBDC investigators mentored another 10 young investigators in research projects directly related to OI. Furthermore, 20 trainees received travel awards to attend the annual scientific meetings of the OIF and the RDCRN's Conference on Clinical Research for Rare Diseases where they had opportunities to present their scientific work. BBDC enhancement activities also ensured that the trainees actively engage with the OIF, the primary patient advocacy group (PAG), and to interact with individuals and families affected by OI. The success of these strategies is best exemplified by the fact that trainees supported by the BBDC have published over 80 publications in the short span of time coinciding with years 1-5 of the BBDC. In addition to these career enhancing activities, the BBDC, in partnership with the OIF, and professional organizations like the American Society for Bone and Mineral Research (ASBMR), National Osteoporosis Foundation, and the Rare Bone Disease Alliance (RBDA), has successfully disseminated information about rare bone diseases and OI to patients, healthcare professionals, and industry partners, thus broadening the impact of the education and training mission of the consortium. The BBDC Career Enhancement Core (CEC) proposes to expand upon the previous training achievements by recruiting and supporting medical students, dentists in training, predoctoral fellows, postdoctoral fellows, genetic counselors, and junior faculty who are interested in rare diseases. To help facilitate a career in rare diseases research, the BBDC CEC will provide a range of career enhancement activities including: 1) procuring protected research time for postdoctoral fellows and junior faculty through the Michael Geisman Fellowship from the OIF, 2) providing didactic training relevant to rare diseases research, 3) engaging the trainees to utilize the data from the longitudinal study to complement the mechanistic data generated in the laboratory, 4) providing opportunities to showcase their research work both within and outside the consortium, and 5) partaking in the community and educational outreach programs of the OIF. The CEC will leverage numerous training resources at its site institutions including: 1) NIH funded Intellectual and Developmental Disabilities Research Centers (IDDRC), Clinical and Translational Science Awards (CTSA), and Training Grants (e.g., K12, K30, and T32 mechanisms), 2) medical and graduate school programs, and 3) educational outreach program of the OIF, to accomplish its goals.

项目概要（职业提升核心） 罕见病临床研究网络（RDCRN）的一个关键目标是培养下一代 罕见病临床/翻译研究者。脆性骨病联盟（BBDC） 在为这一使命作出贡献方面取得了重大进展。在过去的五年里，BBDC为Geisman提供了 研究奖学金资助七个高素质的早期阶段的研究人员（共14个资助的 OIF）。此外，通过利用机构资源，BBDC调查人员指导了另外10名 年轻的研究人员在研究项目直接相关的OI。此外，20名受训人员获得了旅行奖 参加OIF的年度科学会议和RDCRN的罕见病临床研究会议， 在那里他们有机会展示他们的科学工作。BBDC增强活动还 确保学员积极参与OIF，主要患者倡导团体（PAG），并 与受OI影响的个人和家庭互动。这些战略的成功最好的例证是 BBDC支持的学员在短时间内出版了80多本出版物 与BBDC的第1-5年相吻合。除了这些职业发展活动，BBDC，在 与OIF和美国骨矿学会等专业组织合作， 研究（ASBMR），国家骨质疏松症基金会和罕见骨病联盟（RBDA）， 成功地向患者、医疗保健专业人员， 和工业伙伴，从而扩大了联合会教育和培训使命的影响。 BBDC职业提升核心（CEC）建议在以前的培训基础上进行扩展 通过招募和支持医科学生、培训牙医、博士前研究员， 博士后研究员，遗传咨询师和对罕见疾病感兴趣的初级教师。帮助 促进罕见疾病研究的职业生涯，BBDC CEC将提供一系列职业提升 这些活动包括：1）通过为博士后研究员和初级教师提供受保护的研究时间， 法语国家组织的Michael Geisman奖学金，2）提供与罕见疾病研究相关的教学培训，3） 使受训者利用来自纵向研究的数据来补充机制数据 在实验室产生，4）提供机会，展示他们的研究工作内外 该联盟，以及5）参与法语国家国际组织的社区和教育外展计划。中央选举委员会 将利用其网站机构的众多培训资源，包括：1）NIH资助的知识和 发育障碍研究中心（IDDRC），临床和转化科学奖（CTSA）， 和培训赠款（例如，K12，K30和T32机制），2）医学和研究生院课程，以及3） 法语国家组织的教育推广方案，以实现其目标。