Training in Radiation Oncology

放射肿瘤学培训

• 批准号: 7603137
• 负责人: CLIFTON C LING
• 金额: $ 16.62万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603137
• 关键词: Radiation Oncology; Training

DESCRIPTION (provided by applicant): This program for Training in Radiation Oncology Sciences (TROS) is to provide opportunities of laboratory and/or clinical research to clinicians and scientists. The overall objective is to promote the development of full-time academic careers targeted to integrating clinical, biological and physical investigation in radiation oncology, so as to improve the management of cancer. Radiotherapy is a multidisciplinary practice involving radiobiology, medical physics and clinical oncology. Increase in our radiobiological knowledge may further enhance the scientific basis and improve treatment approaches of radiotherapy. The application of advanced physics, computer and engineering technology may also impact on the success of radiotherapy. Optimum integration of these scientific and technical fields into clinical practice requires personnel that are cross-trained in the multiple facets that constitute radiation oncology. A major goal of this program is to contribute to such integration. The participating faculty has career paths that integrate laboratory and clinical research. Thus, they could serve as role models for the potential trainees. In addition, our team is comprehensive and integrated in terms of meshing together the expertise in biology, physics and clinical radiotherapy. One example for such integration is the research of intensity modulated radiotherapy (IMRT), involve computer aided optimization, biophysical modeling and radiobiological investigation, and clinical study. Our research program has three special emphases. The first is in IMRT that involves significant technological advancement, requiring integration of physics, engineering and clinical medicine. The second, in molecular radiobiology, is motivated by the rapid increase in our knowledge of tumor genotype and phenotype with molecular biology approaches. The third is in biological and molecular imaging, which combines our understanding of the molecular basis of cancer and advanced imaging. The mentors of TROS have developed major research programs in these areas. An important goal of this program is to provide resources for training clinicians and scientists in these directions of radiation oncology research and to build the necessary interface between the laboratory and the clinic in the era of molecular medicine.

描述（由申请人提供）：本放射肿瘤学科学（TROS）培训计划旨在为临床医生和科学家提供实验室和/或临床研究的机会。总体目标是促进全日制学术事业的发展，目标是整合放射肿瘤学的临床，生物和物理研究，以改善癌症的管理。放射治疗是一门涉及放射生物学、医学物理学和临床肿瘤学的多学科实践。随着放射生物学知识的增加，放射治疗的科学基础和治疗方法将得到进一步的提高。先进物理学、计算机和工程技术的应用也可能影响放射治疗的成功。将这些科学和技术领域最佳地整合到临床实践中需要在构成放射肿瘤学的多个方面接受交叉培训的人员。该方案的一个主要目标是促进这种融合。参与的教师有职业道路，整合实验室和临床研究。因此，他们可以成为潜在受训者的榜样。此外，我们的团队是全面和综合的啮合在一起的专业知识在生物学，物理学和临床放射治疗方面。调强放射治疗（IMRT）的研究就是这种整合的一个例子，它涉及计算机辅助优化、生物物理建模和放射生物学研究以及临床研究。我们的研究计划有三个特别的重点。第一个是IMRT，它涉及重大的技术进步，需要整合物理学，工程学和临床医学。第二，在分子放射生物学，是由于我们的知识的快速增长的肿瘤基因型和表型的分子生物学方法。第三是生物和分子成像，它结合了我们对癌症分子基础的理解和先进的成像。TROS的导师在这些领域制定了重大研究计划。该计划的一个重要目标是为培训放射肿瘤学研究方向的临床医生和科学家提供资源，并在分子医学时代建立实验室和临床之间的必要接口。