Pre- and Postdoctoral Training in Biochemistry of Aging

衰老生物化学博士前和博士后培训

• 批准号: 7614470
• 负责人: Peter Rudolph Polgar
• 金额: $ 33.18万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-09-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7614470
• 关键词: Aging; Biochemistry; post-doctoral training

DESCRIPTION (provided by applicant): This application requests continuation of a combined pre and postdoctoral training program. Using cutting edge approaches the program focuses on cellular, molecular and genetic biochemistry of aging, addressing such age related areas as the biochemistry of neurodegenerative disease, apoptosis, dermal aging, insulin function, hypertension, connective tissue/inflammation, receptors and bone regeneration. The program is based in the Biochemistry Department but it merges the teaching and research strengths of other basic and clinical departments such as the Geriatric Service, the Boston University Alzheimer's Disease Core Center (ADCC), the departments of Dermatology, Genetics, Pharmacology, Pathology and the Whitaker Hypertension Institute. The teaching and clinical strengths of the Geriatrics Section of the Department of Medicine and the ADCC add to the program by instructing the trainees in the social issues which accompany senescence. Twenty one core faculty members, from the department of biochemistry but also from the above disciplines, participate as mentors in the program. The program is run by an executive committee and reviewed by and advisory committee. The application requests a continuation of the current number of total trainee slots: 4 predoctoral and 4 postdoctoral positions. The research programs of the training faculty as well as the Department of Biochemistry as a whole are very well funded and provide a very good working environment for the trainee. The program includes formal course work, seminars, journal clubs, trainee meetings and presentations and individual research projects that apply to cell and molecular biology of aging within a framework of basic science and clinical and epidemiological aspects of aging. The program has an excellent record. Of the 36 combined past trainees over the last 10 years, 15 are now in academic faculty positions, 11 are in nonacademic research (many are senior scientists) and the rest are still training as postdocs or residents The program is also involved in active minority recruitment. Within the last ten years he program has recruited six minority trainees. Five are now outside the program and doing very well while one is presently in training. This program trains young scientists who plan to dedicate their lives to alleviate or eliminate diseases associated with aging. In addition we expect that many of our trainees will also work on ways to extend human lifespan but with dignity and in comfort.

描述（由申请人提供）：本申请要求继续进行博士前和博士后联合培训计划。使用尖端的方法，该计划侧重于衰老的细胞，分子和遗传生物化学，解决与年龄相关的领域，如神经退行性疾病，细胞凋亡，皮肤老化，胰岛素功能，高血压，结缔组织/炎症，受体和骨再生的生物化学。该项目以生物化学系为基础，但它融合了其他基础和临床部门的教学和研究优势，如老年医学服务、波士顿大学阿尔茨海默病核心中心（ADCC）、皮肤病学、遗传学、药理学、病理学和惠特克高血压研究所。医学部老年病科和ADCC的教学和临床优势通过指导受训人员了解伴随衰老的社会问题，增加了该计划。来自生物化学系和上述学科的21名核心教师作为导师参与该计划。该项目由执行委员会管理，并由咨询委员会审核。申请要求延续目前的培训生名额总数：4个博士预科和4个博士后职位。培训学院和整个生物化学系的研究项目资金充足，为学员提供了良好的工作环境。该项目包括正式的课程作业、研讨会、期刊俱乐部、学员会议、演讲和个人研究项目，这些项目适用于衰老的基础科学、临床和流行病学方面的框架内的细胞和分子生物学。这个项目有很好的记录。在过去10年的36名学员中，15人现在担任学术教职，11人从事非学术研究（其中许多是资深科学家），其余的人仍在接受博士后或住院医师培训。该项目还积极招募少数民族。在过去的十年里，该项目已经招募了6名少数民族学员。其中5人现在已经脱离了这个项目，表现非常好，还有1人目前正在接受培训。这个项目培养年轻的科学家，他们计划将自己的一生奉献给减轻或消除与衰老有关的疾病。此外，我们期望我们的许多学员也将致力于延长人类寿命的方法，但要有尊严和舒适。