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ARTHRITIS AND IMMUNOLOGY

关节炎和免疫学

基本信息

批准号：
7618778
负责人：
JOANNE M. JORDAN
金额：
$ 29.19万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1981
资助国家：
美国
起止时间：
1981-07-01 至 2010-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7618778
关键词：
Arthritis Immunology

项目摘要

DESCRIPTION (provided by applicant): The primary goals of this Rheumatology and Immunology Research Training Program are: a) to provide trainees with a broad investigational experience in laboratory and/or non-laboratory research basic to the study of rheumatic diseases and b) to foster the development of investigative skills in trainees. The program is open to pre-doctoral students, MDs and PhDs interested in disease oriented research and committed to a career in basic and/or clinical research in rheumatic diseases. Trainees will develop a solid background in the molecular and cellular mechanisms of and/or epidemiology of rheumatic diseases and become qualified to embark upon their careers as independent investigators in rheumatology and immunology research. Trainees may select a diverse faculty in the Thurston Arthritis Research Center (TARC) as mentors. All of the mentors are well funded to conduct their research. The training of MD postdoctoral fellows who plan careers in academic rheumatology receives major emphasis. Special efforts are also made to recruit minority candidates. The training program is largely preceptorial, with more than 75% of the trainee's time devoted to independent research activities, supplemented with structured didactics. Ongoing animal and human biomedical research encompasses many of the issues relevant to autoimmunity, arthritis, and musculoskeletal disease. Trainee laboratory research is supported by all of the necessary equipment and resources for modern molecular and cellular immunology, genomics, proteomics, and cell biology. Opportunities in non-laboratory investigation derive from the multiple resources of the Multidisciplinary Clinical Research Center within the TARC and other resources throughout the UNC health sciences campus. The entire curriculum in the Departments of Microbiology/Immunology, Biochemistry and Biophysics, other School of Medicine departments, Epidemiology, Health Behavior & Health Education, and other departments in the School of Public Health are open to trainees. Trainees are required to participate in a variety of seminars and conferences, including a weekly research-in-progress conference where trainees present their research and those dealing with responsible conduct of research. The curriculum for pre-doctoral trainees is tailored to their needs and consists of formal didactics relative to their degree program, as well as others within the structure of our training program. Post-doctoral trainees are encouraged to obtain extramural funding such as NIH K08, K23, R01, and R03 series awards and Arthritis Foundation and to parlay those opportunities into academic careers. The majority of pre- (24 of 24, 100%) and post-doctoral (39 of 44, 89%) trainees in this program over the last 10 years are currently engaged in academic endeavors as trainees, university faculty or industry researchers.

描述（由申请人提供）：本风湿学和免疫学研究培训计划的主要目标是：a）为学员提供风湿性疾病研究基础的实验室和/或非实验室研究的广泛研究经验，以及B）促进学员研究技能的发展。该计划是开放给博士前的学生，医学博士和博士有兴趣在疾病为导向的研究，并致力于在风湿性疾病的基础和/或临床研究的职业生涯。学员将在风湿性疾病的分子和细胞机制和/或流行病学方面建立坚实的背景，并有资格作为风湿病学和免疫学研究的独立研究者开始他们的职业生涯。学员可以选择在瑟斯顿关节炎研究中心（TARC）作为导师多元化的教师。所有的导师都有充足的资金来进行他们的研究。计划从事学术流变学的MD博士后研究员的培训得到了重点关注。还特别努力征聘少数族裔候选人。培训计划主要是指导性的，学员75%以上的时间用于独立研究活动，并辅以结构化教学。正在进行的动物和人类生物医学研究包括许多与自身免疫、关节炎和肌肉骨骼疾病相关的问题。实习生实验室研究得到现代分子和细胞免疫学，基因组学，蛋白质组学和细胞生物学所有必要设备和资源的支持。非实验室调查的机会来自TARC内多学科临床研究中心的多种资源以及整个健康科学校园的其他资源。微生物学/免疫学，生物化学和生物物理学，医学系其他部门，流行病学，健康行为和健康教育以及公共卫生学院其他部门的整个课程都对学员开放。受训人员必须参加各种研讨会和会议，包括每周一次的研究进展会议，受训人员在会上介绍他们的研究成果，并介绍负责进行研究的人员。博士前学员的课程是根据他们的需求量身定制的，包括与他们的学位课程相关的正式教学法，以及我们培训计划结构内的其他课程。鼓励博士后学员获得校外资助，如NIH K 08，K23，R 01和R 03系列奖项和关节炎基金会，并利用这些机会进入学术生涯。在过去的10年里，该计划的大多数博士前（24人中的24人，100%）和博士后（44人中的39人，89%）学员目前正在从事学术工作，作为学员，大学教师或行业研究人员。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Diminished expression of the T cell receptor on the expanded lymphocyte population in MRL/Mp-lpr/lpr mice.

MRL/Mp-lpr/lpr 小鼠中扩增的淋巴细胞群上 T 细胞受体的表达减少。

DOI：
10.3109/08916938909019947
发表时间：
1989
期刊：
Autoimmunity
影响因子：
3.5
作者：
Groghan,TW;Davignon,JL;Evans,J;Allison,JP;Eisenberg,RA;Frelinger,JA;Cohen,PL
通讯作者：
Cohen,PL

Racial/Ethnic differences in quality of life for people living with arthritis who see a primary care physician.

DOI：
10.2174/1874312901105010024
发表时间：
2011-01-01
期刊：
The open rheumatology journal
影响因子：
0
作者：
Carpenter, Delesha M;Schoster, Britta;Callahan, Leigh F
通讯作者：
Callahan, Leigh F

Breast feeding and the development of juvenile rheumatoid arthritis.

DOI：
发表时间：
1995
期刊：
The Journal of rheumatology
影响因子：
0
作者：
T. Mason;Rabinovich Ce;Fredrickson Dd;K. Amoroso;Ann M. Reed;Stein Ld;Kredich Dw
通讯作者：
T. Mason;Rabinovich Ce;Fredrickson Dd;K. Amoroso;Ann M. Reed;Stein Ld;Kredich Dw