Research Core

研究核心

• 批准号: 10713131
• 负责人: Emily Haroz
• 金额: $ 55.68万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10713131
• 关键词: Address; Age; Ally; Area; Automobile Driving; Biological Models; COVID-19 pandemic; Code; Collaborations; Communities; Data; Data Collection; Development; Discipline; Drug usage; Ecosystem; Epidemiology; Equity; Evaluation; Extramural Activities; Fostering; Funding; Future; Gender; Generations; Health; Heterogeneity; Indigenous; Inequity; Institution; Intervention; Journals; Leadership; Measurement; Measures; Methodology; Methods; Modeling; Morbidity - disease rate; Native-Born; Outcome; Personal Satisfaction; Persons; Pharmaceutical Preparations; Pilot Projects; Policies; Prevention Research; Procedures; Process; Productivity; Public Health; Publications; Race; Recovery; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Resources; Sea; Services; Source; Statistical Data Interpretation; System; Training and Education; Trauma; United States; Universities; Work; Writing; addiction; career; community partnership; data management; data sharing; design; disparities in morbidity; falls; healing; health inequalities; implementation science; indigenous community; innovation; intervention effect; mortality; mortality disparity; novel; outcome disparities; personalized approach; programs; recruit; repository; student training; substance abuse prevention; substance use; substance use prevention; symposium; web site

PROJECT SUMMARY Decades of research has failed to address Indigenous drug and other substance use inequities in the United States. These persistent challenges call for new systems and methods to turn the tide on Indigenous substance use prevention, programs, and policies. The Research Core will serve as a central resource for methods support and analyses for CIRCLE's proposed research and evaluation projects designed to build resources and evidence for culture as a core source of healing and prevention of substance use morbidity and mortality disparities resulting from centuries of colonizer-based racial trauma and oppression. The Research Core is led by a team of Indigenous and allied leadership who will provide operational support in Indigenous research methodologies; community partnership and culturally responsive engagement; substance use epidemiology; longitudinal, quantitative, qualitative, and mixed-methods analyses; multilevel and mixture modeling; implementation science; and data management, sovereignty, and stewardship in line with CIRCLE's overall aims and objectives. In addition, the Research Core will advance four methods innovation projects designed to: (1) conceptualize and operationalize “culture” as a key construct for addressing problematic substance use within and across Indigenous communities and settings; (2) characterize novel outcomes and measurement approaches for concepts of pre-addiction and recovery in Indigenous populations; (3) enhance understanding of heterogeneity in interventions, implementation, and policies to inform precision approaches to substance use research with Indigenous communities; and (4) operationalize the Indigenist Ecological Systems Model through creation of a repository of measures and associated resources. The Research Core will also support innovative pilot work by early-career investigators from diverse disciplines and helps them develop pilot research into robust lines of extramurally funded research. Finally, the Research Core will support dissemination of the CIRCLE's methodological advances and research findings in collaboration with the Administrative Core.

项目摘要 数十年的研究未能解决统一的土著药物和其他药物使用不平等 国家。这些持续的挑战要求采取新的系统和方法来扭转土著基板的潮流 使用预防，计划和政策。研究核心将作为方法支持的中心资源 并分析Circle提议的研究和评估项目，旨在建立资源和证据 作为培养作为治疗和预防物质使用的核心来源发病率和死亡率分布 源于数百年来的基于殖民者的种族创伤和观点。研究核心由团队领导 土著和盟友领导人将提供土著研究方法的运营支持； 社区伙伴关系和文化反应迅速的参与；物质使用流行病学；纵向 定量，定性和混合方法分析；多级和混合建模；实施科学； 以及与Circle的整体目标和目标一致的数据管理，主权和管理。在 此外，研究核心还将推进旨在：（1）概念化和 将“文化”运营为解决问题内和跨越问题的物质使用的关键结构 土著社区和环境； （2）表征新的结果和测量方法 土著人口中附加和恢复的概念； （3）增强对异质性的理解 在干预措施，实施和政策中，以告知精确方法进行药物使用研究 土著社区； （4）通过创建土著主义生态系统模型来运营土著主义生态系统模型 测量和相关资源的存储库。研究核心还将支持创新的飞行员工作 来自潜水员学科的早期职业调查员，并帮助他们开发针对强大线条的试点研究 外部资助的研究。最后，研究核心将支持圆圈的传播 方法论的进步和研究结果与行政核心合作。