The Female Reproductive Tract as a Portal of HIV Infection
The Female Reproductive Tract as a Portal of HIV Infection
批准号:
7684926
负责人:
LINDA C GIUDICE
金额:
$47.06万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-01 至 2014-08-31
关键词:
AffectAnimal ModelAnimalsAntiviral AgentsAtrophicBindingBiological AssayBiological ModelsBradykininC 31GCCR5 geneCXCR4 geneCapsidCarrageenanCategoriesCell Surface ReceptorsCell physiologyCellsCellular ImmunityCervicalClinicalClinical DataClinical TrialsCoculture TechniquesColitisCollaborationsContraceptive AgentsCountryDataDecidual Cell ReactionsDepo ProveraDepositionDetergentsDevelopmentElectronicsEndocervixEndometrialEnhancersEnsureEpidemiologic StudiesEpithelialEpithelial CellsEpitheliumExocervixExposure toFDA approvedFailureFemaleFundingFutureGalactosylceramidesGene ExpressionGoalsGrowthGuidelinesHIVHIV InfectionsHIV ReceptorsHealthHeterosexualsHistologyHomeostasisHormonesHumanImmuneImmune responseImmunologyIn VitroInfectionInfiltrationInflammationInflammatoryInformation DistributionInjuryInorganic SulfatesInstitutesIntrauterine DevicesLaboratoriesLegal patentLettersLeukocytesMediatingMediationMethodsModelingMucous MembraneNonoxynol 9PaperPathway interactionsPhase III Clinical TrialsPoliciesPolysaccharidesPre-Clinical ModelPredispositionPrincipal InvestigatorProceduresProductionProgestinsProtein SecretionPubMedPublicationsPublishingReagentResearchResearch PersonnelResistanceResourcesRiskSafetySamplingSan FranciscoScientistSeminal PlasmaSeminal fluidSiteSpermatocidal AgentsStratified Squamous EpitheliumSurfaceTechnical ExpertiseTechniquesTestingTimeTissuesTranslationsUnited States National Institutes of HealthUnited States National Library of MedicineUnspecified or Sulfate Ion SulfatesUshercellVaginaViralWomanWorkcellulose sulfatecondomscytokinedata sharingdissemination researchgenome wide association studyin vitro Assayin vivoinhibitor/antagonistinjuredinterestmalemicrobicidenovelpandemic diseasepreclinical safetyreceptorreproductiveresponsesafety testingsuccesstransmission processtrendvaginal microbicidevirology
中文摘要
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英文摘要
1 of WHP-San Francisco, serves as Director of the Gladstone
Institute of Virology and Immunology.
16. LETTERS OF SUPPORT (e.g., Consultants)
A letter from Dr. Mark Scott, who will provide technical expertise in regards to the handling of endocervical
samples using the Luminex platform, is enclosed on page 133.
17. RESOURCE SHARING
A major benefit of scientific research is its potential translation for the benefit of human health. Rapid
sharing of scientific data and reagents/resources can potentially reduce the time between a discovery and
the effective "translation" of that discovery. Scientific publications are the major mechanism for sharing data
with other scientists and with the public at large. WHP-San Francisco investigators will make their
published work available to interested scientists by submitting an electronic version of their paper to the
National Library of Medicine's PubMed Central upon acceptance for publication. These papers will be
made publicly available no later than 12 months after the official date of publication in accord with NIH
Public Access Policy (NOT-OD-05-022). Similarly, reagents utilized in these publications will be made
freely available to other academic investigators in a timely manner. The sharing of data and resources
serves the best interest of overall scientific progress. When appropriate, patent protection may be sought
for discoveries that may have commercial value. However, patenting procedures should not preclude the
distribution of information or reagents to interested academic investigators, as outlined in the NIH
Guidelines for Dissemination of Research Resources Arising Out of NIH-funded Research. WHP-San
Francisco is dedicated to establishing the appropriate policies and procedures as a well as a culture for
effective sharing of data and resources.
Sharing Model Organisms: Development of model organisms is not planned in the current scope of work
for WHP-San Francisco.
Genome-Wide Association Studies (GWASj: Following publication of findings, microarray data
generated in
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会议论文
Education - Outreach Core
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批准号:10673398
-
项目类别:
-
资助金额:$7.18万
-
财政年份:2023
-
负责人:LINDA C GIUDICE
-
依托单位:
Leveraging Single-Cell Technologies to Elucidate Niche Environments and Immune Mechanisms Involved in Endometriosis Pathogenesis, Pathophysiology, and Disease Stratification
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批准号:10308248
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项目类别:
-
资助金额:$43.48万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Leveraging Single-Cell Technologies to Elucidate Niche Environments and Immune Mechanisms Involved in Endometriosis Pathogenesis, Pathophysiology, and Disease Stratification
-
批准号:10458758
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项目类别:
-
资助金额:$41.73万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
UCSF Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement
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批准号:10699963
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项目类别:
-
资助金额:$134.97万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
UCSF Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement
-
批准号:10308246
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项目类别:
-
资助金额:$144.78万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Administrative Core (Core A)
-
批准号:10308247
-
项目类别:
-
资助金额:$8.04万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Administrative Core (Core A)
-
批准号:10458757
-
项目类别:
-
资助金额:$7.44万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
UCSF Stanford Endometriosis Center for Discovery, Innovation, Training and Community Engagement
-
批准号:10458756
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项目类别:
-
资助金额:$139.88万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Leveraging Electronic Medical Records and Machine Learning Approaches to Study Endometriosis in Diverse Populations
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批准号:10771804
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项目类别:
-
资助金额:$23.14万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Leveraging Single-Cell Technologies to Elucidate Niche Environments and Immune Mechanisms Involved in Endometriosis Pathogenesis, Pathophysiology, and Disease Stratification
-
批准号:10699965
-
项目类别:
-
资助金额:$41.5万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Administrative Core (Core A)
-
批准号:10699964
-
项目类别:
-
资助金额:$6.97万
-
财政年份:2021
-
负责人:LINDA C GIUDICE
-
依托单位:
Integrative Analysis of Genomic, Epigenomic and Phenotypic Data for Disease Stratification of Endometriosis
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批准号:9922328
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项目类别:
-
资助金额:$55.24万
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财政年份:2016
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负责人:LINDA C GIUDICE
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依托单位:
Integrative Analysis of Genomic, Epigenomic and Phenotypic Data for Disease Stratification of Endometriosis
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批准号:9476161
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项目类别:
-
资助金额:$61.31万
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财政年份:2016
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负责人:LINDA C GIUDICE
-
依托单位:
Women's Reproductive Health Research
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批准号:8990636
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项目类别:
-
资助金额:$12.49万
-
财政年份:2015
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负责人:LINDA C GIUDICE
-
依托单位:
Human Endometrial Tissue and DNA Bank
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批准号:8286521
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项目类别:
-
资助金额:$18.35万
-
财政年份:2012
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负责人:LINDA C GIUDICE
-
依托单位:
Development of Human Endometrium for Embryonic Implantation
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批准号:8286513
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项目类别:
-
资助金额:$32.63万
-
财政年份:2012
-
负责人:LINDA C GIUDICE
-
依托单位:
Administrative Core
-
批准号:8286515
-
项目类别:
-
资助金额:$25.57万
-
财政年份:2012
-
负责人:LINDA C GIUDICE
-
依托单位:
Development of Human Endometrium for Embryonic Implantation
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批准号:8519594
-
项目类别:
-
资助金额:$10.04万
-
财政年份:2012
-
负责人:LINDA C GIUDICE
-
依托单位:
Decidual Fibroblast Differentiation and Human Implantation
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批准号:8248071
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项目类别:
-
资助金额:$53.85万
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财政年份:2011
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负责人:LINDA C GIUDICE
-
依托单位:
Exploring HIV-Host Interactions in the Female Reproductive Tract
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批准号:7922623
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项目类别:
-
资助金额:$178.44万
-
财政年份:2009
-
负责人:LINDA C GIUDICE
-
依托单位:
海外基金