The Development and Psychometric Evaluation of the SIRS: A Social Isolation Risk Scale for Survivors of Head and Neck Cancer

SIRS 的发展和心理测量评估：头颈癌幸存者的社会孤立风险量表

• 批准号: 10729500
• 负责人: Allison Marziliano
• 金额: $ 15.66万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-24 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729500
• 关键词: Acute; Address; Aftercare; Anxiety; Assessment tool; Behavioral Research; Body Image; Cancer Center; Cancer Survivor; Cardiovascular Diseases; Choking; Clinic; Clinic Visits; Clinical; Data; Deglutition; Demographic Survey; Development; Disease; Distress; Evaluation; Face; Factor Analysis; Feedback; Gagging; Generations; Goals; Guidelines; Head and Neck Cancer; Health; Impairment; Individual; Interview; Larynx; Loneliness; Longitudinal Studies; Malignant Neoplasms; Measurement; Measures; Mental Depression; Mental Health; Methods; Modeling; Nose; Oral cavity; Oropharyngeal; Outcome; Persons; Pharyngeal structure; Population; Populations at Risk; Prevention strategy; Property; Psyche structure; Psychometrics; Quality of life; Review Literature; Risk; Risk Factors; Screening procedure; Sinus; Social Desirability; Social Development; Social isolation; Societies; Speech; Stroke; Suggestion; Survival Rate; Survivors; Symptoms; Taste Perception; Testing; Time; Treatment Side Effects; United States; Visit; brief screening; evidence base; experience; facial disfigurement; improved; innovation; member; physical conditioning; physical symptom; prevent; recruit; social; survivorship

Head and neck cancer (HNC) survivors have unique survivorship challenges (e.g., facial disfigurement), which often lead to social isolation. To address social isolation and prevent associated negative health outcomes, it is critical to identify HNC survivors at risk for social isolation. Currently, these efforts are hampered by a lack of screening tools that are both sufficiently brief to be used routinely in a fast-paced clinic and capture the risk factors unique to HNC that potentiate social isolation. Hence, the overall purpose of this proposal is to develop and conduct a preliminary psychometric evaluation of the Social Isolation Risk Scale (SIRS), a brief screening tool to identify HNC survivors at risk for social isolation. Aim 1: Develop the SIRS: Item pool generation (1a): Our team will use inductive and deductive methods to generate a pool of potential scale items (i.e., reasons why HNC survivors socially isolate, general social isolation risk factors) through discussions among HNC survivor members of our advisory board, and experts in HNC, social isolation, and measurement, as well as a literature review. Item pool refinement (1b): We will refine the item pool through 1-on-1 interviews with N = 30 socially isolated HNC survivors. We will solicit feedback on item relevance (quantitative scale 1 to 5, higher values indicate more relevance), addition/deletion of items (items will be added/deleted if 70% of those asked endorse addition/deletion), and suggestions for alternative wording via qualitative feedback. At the conclusion of 1b, we will have a ~16-item SIRS (~8 items related to non-physical social isolation risk factors and ~8 items related to physical social isolation risk factors), to undergo preliminary psychometric evaluation during Aim 2b. Aim 2: Administer (2a) and conduct preliminary psychometric evaluation (2b) of the SIRS. 2a. We will conduct a 3-month longitudinal study, in which we will administer the SIRS, a demographic survey, and a battery of validated assessments of social isolation, general distress, loneliness, social connectedness, social desirability, and HNC-related quality of life, to N=130 HNC survivors at their 6-month (T1) and 9-month (T2) post-treatment completion visits. 2b. We will perform preliminary psychometric analyses of the SIRS, evaluating both items’ properties and SIRS’ properties, as well as perform a factor analysis. Based on a priori established guidelines, we will select a final set of items to retain for the SIRS, with the goal of ~10 items in total (~5 items related to physical risk factors and ~5 items related to non- physical risk factors). This project is (a) significant, as it will improve the long-term health of a substantial (at least 36%) subset of HNC survivors and will serve as a model for identifying and preventing social isolation in other at-risk groups; and (b) innovative, as it approaches the problem from a different perspective- focusing on the root cause (i.e., social isolation) of negative outcomes, rather than the negative outcomes themselves.

头颈癌 (HNC) 幸存者面临着独特的生存挑战（例如面部毁容）， 常常导致社会孤立。为了解决社会孤立问题并防止相关的负面健康后果， 对于识别面临社会孤立风险的 HNC 幸存者至关重要。目前，这些努力因缺乏 筛查工具足够简短，可以在快节奏的诊所中常规使用并捕获风险 HNC 特有的因素会加剧社会孤立。因此，本提案的总体目的是 制定并进行社会孤立风险量表（SIRS）的初步心理测量评估， 用于识别有社会孤立风险的 HNC 幸存者的简短筛查工具。目标 1：开发 SIRS：项目池 生成（1a）：我们的团队将使用归纳和演绎方法来生成潜在规模池 项目（即 HNC 幸存者社会孤立的原因、一般社会孤立风险因素） 我们咨询委员会的 HNC 幸存者成员以及 HNC、社会隔离和 测量以及文献综述。物品池细化 (1b)：我们将通过以下方式细化物品池： 对 N = 30 名社会孤立的 HNC 幸存者进行一对一访谈。我们将征求有关项目相关性的反馈 （定量范围1到5，数值越高表示相关性越高），项目的添加/删除（项目将被 如果 70% 的受访者同意添加/删除，则添加/删除），以及替代措辞的建议 定性反馈。在 1b 结束时，我们将拥有约 16 项 SIRS（约 8 项与非物理相关） 社会隔离风险因素和〜8项与身体社会隔离风险因素相关的项目），进行初步 目标 2b 期间的心理测量评估。目标 2：管理 (2a) 并进行初步心理测量 SIRS 的评估（2b）。 2a.我们将进行为期 3 个月的纵向研究，其中我们将管理 SIRS，一项人口统计调查，以及一系列针对社会孤立、普遍困扰、 N=130 名 HNC 幸存者的孤独感、社会联系性、社会愿望以及与 HNC 相关的生活质量 他们的 6 个月 (T1) 和 9 个月 (T2) 治疗完成后访视。 2b.我们将进行初步的 对 SIRS 进行心理测量分析，评估项目属性和 SIRS 属性，并执行 因素分析。根据先验制定的指南，我们将选择一组最终保留的项目 SIRS，目标总共约 10 项（约 5 项与身体风险因素相关，约 5 项与非危险因素相关） 身体危险因素）。该项目 (a) 意义重大，因为它将改善大量（在 至少 36%）的 HNC 幸存者子集，并将作为识别和防止社会孤立的模型 其他高危人群； (b) 创新，因为它从不同的角度处理问题——重点关注 负面结果的根本原因（即社会孤立），而不是负面结果本身。