Idiographic Examination of Alcohol to Dampen Positive Emotions for Co-morbid Alcohol Use and PTSD

项目摘要/摘要 创伤后应激障碍(PTSD)和酒精使用障碍(AUD)同时发生的频率很高(24- 61%)。 创伤后应激障碍 角色 有 情绪 建议 监管) 较少 通过饮酒。对这些发现的一种解释是 这种并存现象具有相当大的临床意义。合并PTSD-AUD的个体(vs. 或仅有澳元)报告更多的创伤后应激障碍症状和更糟糕的酒精结果。研究强调 在创伤后应激障碍和AUD并存时的情绪过程。然而，此前对这一领域的调查 范围狭窄，几乎完全集中在负面情绪上。关于正性的有限研究 声称酒精使用在上调(引发/增加)积极情绪方面起到了作用。我们的试点数据 有创伤后应激障碍症状的人饮酒也可能是出于逃避(向下- 积极的情绪。我们发现，有创伤后应激障碍症状的创伤暴露者 接受积极的情绪，更有可能参与Fforts以避免积极的情绪，包括 积极的情绪引发了生理上的 E 唤醒，那就是 与创伤相关症状有关，因此在有创伤后应激障碍症状的个人中被评估为厌恶。 这个 流程 目前的方案将利用密集的L纵向数据来评估动态化和具体化 在积极的情绪过程中，饮酒和日常生活中出现的创伤后应激障碍症状 在经常饮酒并经历创伤后应激障碍症状的创伤暴露社区个人中(N=150)。 生态瞬时评估(EMA)将实时捕捉在自然环境中的瞬时过程， 最大化 配置文件。 研究结果的生态效度和概括性。具体分析将识别个性化风险 这些方法将提供必要的数据，以告知具体的创伤后应激障碍和UD干预措施 可以在微观层面上实施。目标1确定创伤后应激障碍症状与 饮酒可以在瞬间下调积极的情绪。目的2使用摄影分析来 识别酒精的特征，以下调与创伤后应激障碍相关的积极情绪。探索性目标 评估酒精使用来下调积极情绪是否有别于其他饮酒动机。 这项研究的发现有可能改变医疗保健实践。一般的做法是 在PTSD-AUD干预中增加积极情绪。如果我们的试点工作得到确认，饮酒有助于 下调那些有创伤后应激障碍症状的人的积极情绪，临床医生可能首先想要评估不良情绪 在PTSD-AUD干预中对积极情绪的反应，并在有指示的情况下解决这些担忧。 这项拟议的研究利用了一种创新的方法来填补在联合治疗机制方面的重大空白。 发生PTSD-AUD。这项工作是重要的、及时的、具有创新性的。在创伤中预防创伤后应激障碍- 受辐射的个人对我国人民的健康和福祉具有重要影响。

PROJECT SUMMARY/ABSTRACT Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) co-occur with high frequency (24- 61%). PTSD role have emotions suggest regulation) less via alcohol use. One explanation for these findings is This co-occurrence has considerable clinical significance. Individuals with co-occurring PTSD-AUD (vs. or AUD alone) report more PTSD symptoms and worse alcohol outcomes. Research emphasizes the of emotional processes in the co-occurrence of PTSD and AUD. However, prior investigations in this area been narrow in scope, focusing almost exclusively on negative emotions. The limited research on positive purports a role of alcohol use in up-regulating (eliciting/increasing) positive emotions. Our pilot data that alcohol use among individuals with PTSD symptoms also may be motivated by avoidance (down- of positive emotions . We have found that trauma-exposed individuals with PTSD symptoms are accepting of positive emotions, and more likely to engage in fforts to avoid positive emotions, including that positive emotions elicit physiological e arousal that is linked to trauma-related symptoms and thus evaluated as aversive among individuals with PTSD symptoms. The processes current proposal will leverage intensive l ongitudinal data t o evaluate dynamic and idiographic among positive emotional processes, alcohol use, and PTSD symptoms as they unfold in daily life among trauma-exposed community individuals who regularly drink and experience PTSD symptoms (N=150). Ecological momentary assessment (EMA) will capture momentary processes in real-time & in natural settings, maximizing profiles. ecological validity and generalizability of findings. Idiographic analysis will identify personalized risk These approacheswill provide the necessary data to inform idiographic PTSD-AUD interventions that can be implemented at the microlevel. Aim 1 determines the extent to which PTSD symptoms are related to alcohol use to down-regulate positive emotions at the momentary level. Aim 2 usesidiographic analysis to identifypatterns of alcohol to down-regulate positive emotions in relation to PTSD. An Exploratory Aim assesses whether alcohol use to down-regulate positive emotions is distinct from other motives for alcohol use. The findings of this research have the potential to transform health care practice. General practice is to increase positive emotions in PTSD-AUD intervention. If our pilot work is confirmed, and alcohol use serves to down-regulate positive emotions in those with PTSD symptoms, clinicians may first want to evaluate adverse reactions to positive emotions in PTSD-AUD intervention, and, if indicated, address those concerns. The proposed research utilizes an innovative approach to fill significant gaps regarding mechanisms in co- occurring PTSD-AUD. This work is important, timely, and innovative. Preventing PTSD-AUD among trauma- exposed individuals has important implications for the health and well-being of people in our nation.