Research Education Component

计划摘要-研究及教育部分 阿尔茨海默病（AD）造成的巨大痛苦、残疾和寿命损失， AD相关痴呆（AD/ADRD）是一个全球性的危机。西班牙裔美国人的风险更高， AD/ADRD，不太可能接受护理，也不太可能参与旨在减少AD/ADRD的研究和服务工作。 AD/ADRD的健康差异高于非西班牙裔白色人。这一点尤其明显， 居住在格兰德河山谷（RGV）的西班牙裔美国人，该地区被列为持续贫困地区， 医疗服务不足，那里的痴呆症发病率是全国最高的。 接触和研究这一人群需要文化上协调一致和受过适当培训的调查人员， 准备推进社会，行为和社区参与的研究与翻译的影响。那里 同时也需要使AD/ADRD研究队伍多样化， 许多社区的成员、身份、种族、族裔、背景、能力、文化和信仰， 包括服务不足的社区，这些社区组成了美国人民。AD/ADRD-RCMAR的研究 德克萨斯大学RGV（UTRGV）的教育组件（REC）实施了一项全面的 研究教育计划有两个总体目标：1）准备早期职业生涯的多元化机构 初级教师成长为持久的职业生涯作为成功的研究科学家，和2）在一个 了解不断增长的美国西班牙裔AD/ADRD健康差异知识体系的有效方式 人口，特别是老龄化的墨西哥裔美国人，沿着德克萨斯州和墨西哥边境的格兰德河山谷 南德克萨斯州REC将利用经验丰富，成功， 这些领域的跨学科研究人员和领导者，以实现以下具体目标：（1）确定和 支持创新试点项目，重点关注AD/ADRD的社会或行为问题、方面或相关因素 在少数民族中。(2)支持试点项目赠款接受者继续发展为研究人员。 (3)提供赠款准备、管理和预算方面的培训。(4)提供一系列 教学/研讨会：a）健康差异研究调查; B）AD/ADRD-RCMAR核心和关键独特的 研究资源及其在AD/ADRD健康差异研究中的潜在应用; c）AD/ADRD 在德克萨斯州的研究;和d）负责任的研究行为。(5)提供持续的指导。完成 这些目标，我们已经建立了一个领导团队，在研究教育，规划和 评估指导，并领导旨在改善的跨学科合作研究工作 少数民族和西班牙裔的健康在目标地理人群，我们已经占了所有需要的 行政和后勤支助。学员和学员将参与并受益于丰富的沉浸式 在开发针对AD/ADRD的社会和行为贡献者的合作研究方面的经验 以及它对RGV的贫困地区，主要是西班牙裔美国-墨西哥边境地区的影响。

Project Summary – Research Education Component The overwhelming burden of suffering, disability, and years of life lost due to Alzheimer’s disease (AD) and AD-related dementias (AD/ADRD) represent a global crisis. Hispanic Americans are at higher risk for AD/ADRD and less likely to receive care and participate in research and service efforts designed to decrease health disparities in AD/ADRD than their non-Hispanic White counterparts. This is particularly evident among Hispanic Americans residing in the Rio Grande Valley (RGV), an area classified as persistent poverty and medically underserved, where the prevalence of dementia is among the highest in the country. Reaching and studying this population requires culturally-attuned and appropriately-trained investigators who are prepared to advance social, behavioral, and community-engaged research with translational impact. There is an equally great concomitant need to diversify the AD/ADRD research workforce, increasing representation of members of the many communities, identities, races, ethnicities, backgrounds, abilities, cultures and beliefs, including underserved communities, that make up the American people. The AD/ADRD-RCMAR’s Research Education Component (REC) at the University of Texas RGV (UTRGV) puts into place a comprehensive research education program with two overarching objectives: 1) to prepare a diverse body of early-career junior faculty to grow into enduring careers as successful research scientists, and 2) to contribute in an impactful way to the body of knowledge on health disparities in AD/ADRD among the growing US Hispanic population, particularly aging Mexican Americans, along the Texas-Mexico border in the Rio Grande Valley and South Texas. The REC will leverage the research expertise and resources of experienced, successful, interdisciplinary investigators and leaders in these fields to achieve the following specific aims: (1) Identify and support innovative pilot projects, focused on social or behavioral problems, aspects, or correlates of AD/ADRD in minority populations. (2) Support the continued development of pilot project grant recipients as researchers. (3) Provide training in grant preparation, administration, and budgeting. (4) Provide a series of didactics/seminars on: a) Health disparities research survey; b) AD/ADRD-RCMAR Cores and key unique research resources and their potential application to AD/ADRD health disparities research; c) AD/ADRD research in Texas; and d) responsible conduct of research. (5) Provide continued mentoring. To accomplish these goals, we have built a leadership team with extensive experience in research education, planning and evaluation of mentoring, and leadership of collaborative interdisciplinary research efforts aimed at improving minorities' and Hispanics' health in targeted geographic populations, and we have accounted for all needed administrative and logistic support. Trainees and mentees will engage in and benefit from a rich immersive experience in developing collaborative research addressing social and behavioral contributors to AD/ADRD and its impacts in the poverty-stricken, primarily Hispanic US-Mexico border region of the RGV.