UCSF Older Americans Independence Center

加州大学旧金山分校美国老年人独立中心

• 批准号: 10729111
• 负责人: KENNETH E. COVINSKY
• 金额: $ 123.13万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729111
• 关键词: Acceleration; Achievement; Address; Advance Care Planning; Affect; Aging; American; Area; Award; Capsicum; Caregivers; Caring; Clinical; Clinical Research; Collaborations; Communities; Complex; Consultations; Data; Data Sources; Dedications; Dermatology; Development; Diabetes Mellitus; Disabled Persons; Discipline; Education; Elderly; Enrollment; Ensure; Fostering; Funding; Future; Geriatrics; Goals; Guidelines; HIV; Healthcare; Homelessness; Hospitals; Impaired cognition; Imprisonment; Internet; Journals; Leadership; Malignant Neoplasms; Mentors; Mentorship; Mission; Neurology; Nursing Homes; Older Population; Oncology; Operative Surgical Procedures; Outcome; Outcomes Research; Patients; Persons; Pilot Projects; Policies; Poverty; Publications; Quality of life; Research; Research Methodology; Research Personnel; Research Support; Resources; Risk; Science; Screening for cancer; Social Interaction; Social isolation; Structure; Sum; Translating; Vulnerable Populations; Work; advanced disease; career development; clinical practice; community center; cost; data resource; disability; disability risk; experience; forging; improved; improved outcome; innovation; instrument; interdisciplinary collaboration; literacy; medical specialties; medical vulnerability; multiple chronic conditions; next generation; prevent; prognostic; programs; safety net; social vulnerability; success; therapy development; tool; user-friendly; web site; web-based tool

PROJECT SUMMARY ABSTRACT – Overall UCSF Older Americans Independence Center (OAIC) The UCSF OAIC theme is "Predictors, Outcomes, and Amelioration of Late-life Disability: A Focus on Vulnerable Populations." Late-life disability will affect 80% of older Americans, has a profound impact on patient and caregiver quality of life, and carries large costs. These challenges have special resonance for older adults who are vulnerable, which we conceptualize as a complex interplay of both medical vulnerability (such as cancer in persons with complex multimorbidity) and social vulnerability (such as social isolation or poverty). We are deeply committed to advancing the science of preventing and ameliorating disability in older adults with these vulnerabilities, in large part by mentoring and supporting the future leaders of aging science who will develop this theme. During our first 9 years, the UCSF OAIC has supported and mentored an interdisciplinary community of investigators whose paradigm-shifting research that has changed clinical practice and policy and yielded major advances in our understanding of disability, including elucidating inextricable linkages between medical and social vulnerabilities. We have been a galvanizing force at UCSF, infusing aging science into a wide array of specialties and disciplines. Our dedication to developing the next generation of researchers has led to publications in the highest impact journals, R01 awards, an unprecedented number of GEMSSTAR and Beeson Awards, and mentorship awards for OAIC Leaders. During the next cycle, we will build on our track record of success while growing and innovating in new directions to respond to emerging opportunities. Our two resource cores – the Data and Analysis Core (DAC) and the Vulnerable Aging Research Core (VARC) - will catalyze a wide spectrum of clinical and outcomes research. Our Research and Education Component (REC) Scholars and Pilot and Exploratory Studies (PESC) Scholars will be provided the resources, mentorship, and community to build a platform for long-term research success in our theme area. Our Leadership and Administration Core (LAC) will guide the Center's activities and mission and ensure tight integration between all of our Cores and activities. Together, we will advance our center's 5 aims: to (1) Catalyze research on disability in vulnerable older persons by serving as a hub that brings together scholars and leverages resources to advance aging disability science and career development; (2) Provide core access to data resources, statistical support, and expertise enrolling and retaining vulnerable older subjects in order to stimulate new research on disability; (3) Identify the future leaders of geriatrics research and catalyze their development with career development funding and exceptional mentoring; (4) Support pilot studies that accelerate aging science and lead to research funding in late life disability; and (5) Develop a leadership and administrative structure that spurs interdisciplinary collaboration, making the OAIC greater than the sum of its parts.

项目摘要摘要 - UCSF总体美国人独立中心（OAIC） UCSF OAIC主题是“晚期残疾的预测，结果和改善：重点 脆弱的人口。”晚期残疾将影响80％的美国人，对 患者和护理人员的生活质量，并带来了巨大的成本。这些挑战具有特殊的共鸣 脆弱的成年人，我们将其概念化为两种医学脆弱性的复杂相互作用（这样 作为具有复杂多发病的人的癌症）和社会脆弱性（例如社会隔离或贫困）。 我们深切致力于预防和改善老年人的残疾科学 这些脆弱性在很大程度上是通过心理和支持未来老化科学领导者的来源 开发这个主题。在我们的头9年中，UCSF OAIC支持并指导了一个跨学科 调查人员的社区，其范式转移研究改变了临床实践和政策， 在我们对残疾的理解方面取得了重大进步，包括阐明 医疗和社会脆弱性。我们一直是UCSF的镀锌力量，将衰老科学注入 广泛的专业和学科。我们致力于发展下一代研究人员 导致了最高影响期刊的出版物，R01奖项，前所未有的GEMSSTAR和 Beeson奖和欧盟领导人的Mentalship Awards。 在下一个周期中，我们将基于成功的记录，同时发展和创新 响应新兴机会的指示。我们的两个资源核心 - 数据和分析核心（DAC） 以及脆弱的老化研究核心（VARC） - 将催化广泛的临床和结果 研究。我们的研究和教育部分（REC）学者，飞行员和探索性研究（PESC） 将为学者提供资源，指导和社区，以建立长期研究的平台 在我们的主题领域的成功。我们的领导力和管理核心（LAC）将指导中心的活动 和任务，并确保我们所有的核心和活动之间紧密整合。在一起，我们将推进我们的 中心的5个目标：（1）通过作为一个枢纽来催化脆弱老年人的残疾研究 汇集了学者，并利用资源来推动老龄化的残疾科学和职业发展； （2）提供核心访问数据资源，统计支持以及注册和保留脆弱的专业知识 较老的受试者以刺激有关残疾的新研究； （3）确定老年医学的未来领导者 研究并通过职业发展资金和出色的心理来促进他们的发展； （4） 支持试点研究，以加速衰老科学并导致晚期残疾的研究资金； （5） 开发一种领导和行政结构，刺激跨学科合作，使OAIC成为OAIC 大于其部分的总和。

项目成果

The growing geriatric prison population: A dire public health consequence of mass incarceration.

• DOI: 10.1111/jgs.17454
• 发表时间: 2021-12
• 期刊: Journal of the American Geriatrics Society
• 影响因子: 6.3
• 作者: Williams B;DiTomas M;Pachynski A
• 通讯作者: Pachynski A

Cancer Screening in Older Adults: Individualized Decision-Making and Communication Strategies.

• DOI: 10.1016/j.mcna.2020.08.002
• 发表时间: 2020-11
• 期刊: The Medical clinics of North America
• 作者: Kotwal AA;Walter LC
• 通讯作者: Walter LC

Long-term individual and population functional outcomes in older adults with atrial fibrillation.

患有房颤的老年人的长期个人和群体功能结果。

• DOI: 10.1101/2020.11.05.20223297
• 发表时间: 2020
• 期刊: medRxiv : the preprint server for health sciences
• 作者: Parks,AnnaL;Jeon,SunY;Boscardin,WJohn;Steinman,MichaelA;Smith,AlexanderK;Fang,MargaretC;Shah,SachinJ
• 通讯作者: Shah,SachinJ

Antihypertensive Medication and Fracture Risk in Older Veterans Health Administration Nursing Home Residents.

老年退伍军人健康管理局疗养院居民的抗高血压药物和骨折风险。

• DOI: 10.1001/jamainternmed.2024.0507
• 发表时间: 2024
• 期刊: JAMA internal medicine
• 影响因子: 39
• 作者: Dave,ChintanV;Li,Yongmei;Steinman,MichaelA;Lee,SeiJ;Liu,Xiaojuan;Jing,Bocheng;Graham,LauraA;Marcum,ZacharyA;Fung,KathyZ;Odden,MichelleC
• 通讯作者: Odden,MichelleC

COVID-19 outbreak in a state prison: a case study on the implementation of key public health recommendations for containment and prevention.

• DOI: 10.1186/s12889-022-12997-1
• 发表时间: 2022-05-14
• 期刊: BMC PUBLIC HEALTH
• 影响因子: 4.5
• 作者: Duarte, Catherine;Cameron, Drew B.;Kwan, Ada T.;Bertozzi, Stefano M.;Williams, Brie A.;McCoy, Sandra I.
• 通讯作者: McCoy, Sandra I.