课题基金 / 基金详情

Recruiting multiethnic populations to preclinical Alzheimers disease trials-Diversity Supplement

Recruiting multiethnic populations to preclinical Alzheimers disease trials-Diversity Supplement
招募多种族人群参加临床前阿尔茨海默病试验-多样性补充
批准号:
10791432
负责人:
Joshua Grill
金额:
$9.34万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-08-15 至 2025-04-30

项目摘要

项目成果

Joshua Grill的其他基金

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中文摘要
翻译
家长研究项目摘要
英文摘要
Abstract of Parent Research Project Alzheimer’s disease (AD) and related dementias (ADRD) disproportionately affect underrepresented racial and ethnic communities. The number of people with Alzheimer’s is expected to increase in the coming years, and with this an increased burden to the public health system. To alleviate this, it is important to find treatments through clinical trials that can slow disease progression, especially in diverse populations. Preclinical AD trials lack diversity, and the trial requirements of learning one’s biomarker status and needing a study partner to enroll could play a role. Our project focuses on understanding how the impact of these preclinical trial requirements, biomarker disclosure and study partner requirement, differs among racial and ethnic groups. We will use cognitive interviews to test our hypothesis that racial and ethnic groups differ in their willingness to learn biomarker status. We will also use a previously developed assessment instrument1, to assess attitudes toward the study partner requirement among diverse groups. We believe that the study partner requirement differentially affects ability/willingness to participate among racial and ethnic groups. This work will help us collect data to guide recruitment in preclinical AD trials in underrepresented groups, better understand attitudes toward biomarker disclosure during the research process and understand the differences in attitudes toward the study partner requirement so investigators can adjust to help underrepresented groups fill this role.
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会议论文
Patient and Family Member Reactions to Biomarker-Informed ADRD Diagnoses
Collaborative Approach for Asian Americans, Native Hawaiians, and Pacific Islanders Research and Education (CARE) 2.0
Summer Medical student Aging and Alzheimer disease Research Training (SMAART) program
  • 批准号:
    10617758
  • 项目类别:
  • 资助金额:
    $6.85万
  • 财政年份:
    2022
  • 负责人:
    Joshua Grill
  • 依托单位:
NIA/AA for Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (NIA/AA IMPACT-AD Course)