Development of Therapeutic Products for Marburg Virus

马尔堡病毒治疗产品的开发

• 批准号: 10787970
• 负责人: M Javad Aman
• 金额: $ 169.6万
• 依托单位: ABVACC, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-17 至 2025-12-16
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10787970
• 关键词: Advanced Development; Categories; Chemistry; Clinical; Development; Emerging Communicable Diseases; Marburgvirus; National Institute of Allergy and Infectious Disease; Pathway interactions; efficacy evaluation; manufacture; pre-clinical; priority pathogen; product development; research and development; safety assessment; therapeutic candidate; therapeutic development

To support the advanced development of a promising candidate therapeutic for NIAID Category A, B, and C Priority Pathogens or emerging infectious diseases. The research and development activities to be supported will allow the candidate therapeutic product to progress through the product development pathway, and include preclinical and IND enabling development activities, chemistry optimization/development, GMP manufacturing, and clinical safety and efficacy assessment.

支持NIAID a、B、C类优先病原体或新发感染性疾病有前景的候选治疗药物的开发。支持的研发活动将允许候选治疗产品通过产品开发途径取得进展，包括临床前和IND开发活动，化学优化/开发，GMP制造以及临床安全性和有效性评估。