On the Hunt: Boosting Productivity of Cell Factories by Advanced Searches

这个项目旨在促进我们对酵母、工业主力和模式生物中潜在的蛋白质分泌分子机制的基本理解。它将开发一个独特的多方面研究平台，在单细胞水平上识别和分析具有所需特性的优良酵母菌株。预期成果包括高通量菌株分析的新分析工具和酵母分子生物学的先进知识，这些知识可用于改善下一代燃料、食品和药品的细胞工厂。这将通过促进生物技术产业的增长，促进向可持续社会的过渡，并改善澳大利亚的生物安全，提供显著的经济和社会效益。

This project aims to advance our fundamental understanding of molecular mechanisms underlying protein secretion in yeast, an industrial workhorse and a model organism. It will develop a unique multifaceted research platform to identify and analyse superior yeast strains with the desired traits at the single-cell level. Expected outcomes include a new analytical tool for high-throughput strain analysis and advanced knowledge of yeast molecular biology that can be applied to improve cell factories for the next generation of fuels, food and pharmaceuticals. This will provide significant economic and social benefits by boosting biotech industry growth, facilitating the transition to a sustainable society and improving Australia’s biosecurity.