An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer

电子健康干预措施可改善完成乳腺癌积极治疗的西班牙裔女性的症状负担和健康相关的生活质量

• 批准号: 9333329
• 负责人: BETINA YANEZ
• 金额: $ 14.39万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9333329
• 关键词: Address; Advanced Malignant Neoplasm; Affect; African American; Aftercare; Age; Belief; Breast Cancer Education; Breast Cancer Treatment; Breast Cancer survivor; Cancer Burden; Cancer Etiology; Cancer Patient; Cancer Survivor; Cardiovascular Diseases; Cause of Death; Cellular Phone; Cessation of life; Chicago; Communication; Coping Skills; Data; Diagnosis; Distress; Evaluation; Evidence based intervention; Face; Health; Health Services Accessibility; Healthcare; Hispanics; Insurance Coverage; Intervention; Intervention Studies; Knowledge; Logistics; Longitudinal Studies; Malignant Neoplasms; Methodology; Methods; Minority Groups; Names; Not Hispanic or Latino; Outcome; Participant; Patient Outcomes Assessments; Patients; Persons; Phase; Psychiatric Social Work; Randomized; Recruitment Activity; Reporting; Resources; Sample Size; Services; Socioeconomic Factors; Survivors; Symptoms; Technology; Testing; Time; Underserved Population; Woman; Work; active method; base; breast cancer diagnosis; cancer diagnosis; cancer therapy; cost; critical period; depressive symptoms; design; eHealth; ethnic minority population; evidence base; experience; handheld mobile device; health equity; health related quality of life; improved; innovation; malignant breast neoplasm; negative affect; novel; patient population; primary outcome; psychoeducation; psychoeducational; psychosocial; randomized trial; reduce symptoms; secondary outcome; skills; stress management; survivorship; symptomatic improvement; therapy design; tool; usability

An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer Abstract Among Hispanics, the largest and fastest growing ethnic minority group in the U.S., cancer is the leading cause of death whereas cardiovascular disease is the leading cause of death for African Americans and non- Hispanic Whites (NHWs). Hispanics also experience substantially lower rates of 5-year cancer-specific survival relative to non–Hispanic Whites (NHWs). Hispanic cancer patients in the U.S. also report significantly worse cancer-related symptom burden and health-related quality of life (HRQOL) than NHWs, even after adjusting for socioeconomic factors. Despite this, very few randomized, intervention studies have specifically targeted cancer-related symptom burden and HRQOL outcomes among Hispanic women, especially during the period at the end of active treatment which is a critical period to intervene to provide skills and tools to assist with this transition. Innovative approaches to providing interventions such as Smartphone technology are especially important for this patient population. Ubiquitous Smartphone use among ethnic minorities in the US provide a unique opportunity to implement a pragmatic technology- and evidence-based psychosocial intervention that overcomes some access to care barriers as well as time and logistical constraints. Furthermore, given that Hispanics own Smartphones and seek health information online from a mobile device at similar or higher rates than other groups in the U.S., Smartphone interventions offer an opportunity to overcome obstacles to accessing resources and services that can be culturally informed and provide skills to improve symptom burden and HRQOL. This study aims to create and evaluate Mi Guía (My Guide), a culturally informed eHealth psychoeducational and psychosocial intervention for English or Spanish-speaking Hispanic women completing treatment for breast cancer. Mi Guía is grounded in evidence-based paradigms to improve our Primary Outcomes: Cancer-Related Symptom Burden and HRQOL and our Secondary Outcomes: usability and markers of Mi Guía use. We propose a two-phase study to develop our Smartphone-based intervention that can be disseminated to cancer survivors at a relatively low cost. We will use innovative methodology; MOST framework that will allow us to achieve both optimization and evaluation of Mi Guía by determining which single components or combination of components in Mi Guía affect our outcomes. Study components (one component on breast cancer psychoeducation, two psychosocial evidence-based components relevant to Hispanic BCS) will be paired with personal tele-coaching among BCS. Our Aims are: Aim 1:(Phase 1): Create Mi Guía, an eHealth intervention designed to improve cancer-related symptom burden and HRQOL. Aim 2: (Phase 2): Optimize components for Mi Guía through a 9-week randomized trial to evaluate three evidence- based intervention components relevant to Hispanic BCS. It is hypothesized that each single intervention component will improve cancer-related symptom burden and HRQOL and that combined intervention components will have a greater effect on our outcomes than single components.

一种电子健康干预措施，以改善症状负担和与健康相关的生活质量 在完成乳腺癌积极治疗的西班牙裔妇女中 抽象的 在西班牙裔，是美国最大，最快增长的少数民族群体，癌症是领先的 死亡原因，而心血管疾病是非洲裔美国人和非 - 西班牙裔白人（NHWS）。西班牙裔也经历了5年特异性生存率的速度大大降低 相对于非西班牙裔白人（NHWS）。美国的西班牙癌患者也报告明显更糟 与NHW相比，与癌症相关的症状伯恩和与健康相关的生活质量（HRQOL），即使调整后， 社会经济因素。尽管如此，很少有随机的干预研究专门针对 西班牙裔妇女中与癌症相关的症状伯恩和HRQOL结果，尤其是在此期间 在积极治疗结束时，这是干预以提供技能和工具来协助此事的关键时期 过渡。尤其是提供智能手机技术等干预措施的创新方法 对这个患者人群很重要。美国少数民族中无处不在的智能手机使用 实施实用务实的技术和基于证据的社会心理干预的独特机会 克服了一些获得护理障碍以及时间和后勤约束的机会。此外，鉴于这一点 西班牙裔拥有智能手机，并以类似或更高的价格从移动设备上在线寻求健康信息 与美国其他团体相比，智能手机干预措施为克服障碍提供了机会 访问可以在文化上获悉的资源和服务，并提供技能以改善症状 负担和HRQOL。这项研究旨在创建和评估MiGuía（我的指南），这是一种文化知情的eHealth 对英语或西班牙语的西班牙裔妇女完成的心理教育和心理社会干预 治疗乳腺癌。 MiGuía以证据的范例为基础，以改善我们的主要 结果：与癌症相关的症状负担和HRQOL以及我们的次要结果：可用性和 MiGuía的标记使用。我们提出了一项两阶段的研究，以开发基于智能手机的干预措施 可以以相对较低的成本将其传播到癌症存活中。我们将使用创新的方法；最多 通过确定哪个单一 MiGuía中组成部分的组成部分或组合会影响我们的结果。研究组件（一个 乳腺癌心理教学的组成部分，两个与 西班牙裔BCS）将与卑诗省的个人电视台配对。我们的目标是：目标1 ：（阶段1）：创建 MiGuía，一种旨在改善与癌症相关的症状伯恩和HRQOL的eHealth干预措施。目标2： （第2阶段）：通过为期9周的随机试验优化MiGuía的组件，以评估三个证据 - 与西班牙裔BC相关的基于干预组件。假设每个干预 组件将改善与癌症相关的症状伯恩和HRQOL，并将其合并干预 组件将对我们的结果产生更大的影响。