An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer

电子健康干预措施可改善完成乳腺癌积极治疗的西班牙裔女性的症状负担和健康相关的生活质量

• 批准号: 9044502
• 负责人: BETINA YANEZ
• 金额: $ 13.12万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-24 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9044502
• 关键词: Address; Advanced Malignant Neoplasm; Affect; African American; Aftercare; Age; Belief; Breast; Breast Cancer Education; Breast Cancer Treatment; Breast Cancer survivor; Cancer Etiology; Cancer Patient; Cancer Survivor; Cardiovascular Diseases; Cause of Death; Cellular Phone; Cessation of life; Chicago; Communication; Coping Skills; Data; Diagnosis; Distress; Evaluation; Evidence based intervention; Face; Health; Health Services Accessibility; Healthcare; Hispanics; Insurance Coverage; Intervention; Intervention Studies; Knowledge; Longitudinal Studies; Malignant Neoplasms; Methodology; Methods; Minority Groups; Names; Not Hispanic or Latino; Outcome; Participant; Patient Outcomes Assessments; Patients; Persons; Phase; Psychiatric Social Work; Randomized; Recruitment Activity; Relative (related person); Reporting; Resources; Sample Size; Services; Socioeconomic Factors; Staging; Survivors; Symptoms; Technology; Testing; Time; Underserved Population; Woman; Work; abstracting; active method; base; breast cancer diagnosis; cancer diagnosis; cancer therapy; cost; critical period; depressive symptoms; design; eHealth; ethnic minority population; evidence base; experience; handheld mobile device; health equity; health related quality of life; improved; innovation; malignant breast neoplasm; novel; patient population; primary outcome; psychoeducation; psychoeducational; psychosocial; randomized trial; secondary outcome; skills; socioeconomics; stress management; survivorship; therapy design; tool; usability

An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer Abstract Among Hispanics, the largest and fastest growing ethnic minority group in the U.S., cancer is the leading cause of death whereas cardiovascular disease is the leading cause of death for African Americans and non- Hispanic Whites (NHWs). Hispanics also experience substantially lower rates of 5-year cancer-specific survival relative to non–Hispanic Whites (NHWs). Hispanic cancer patients in the U.S. also report significantly worse cancer-related symptom burden and health-related quality of life (HRQOL) than NHWs, even after adjusting for socioeconomic factors. Despite this, very few randomized, intervention studies have specifically targeted cancer-related symptom burden and HRQOL outcomes among Hispanic women, especially during the period at the end of active treatment which is a critical period to intervene to provide skills and tools to assist with this transition. Innovative approaches to providing interventions such as Smartphone technology are especially important for this patient population. Ubiquitous Smartphone use among ethnic minorities in the US provide a unique opportunity to implement a pragmatic technology- and evidence-based psychosocial intervention that overcomes some access to care barriers as well as time and logistical constraints. Furthermore, given that Hispanics own Smartphones and seek health information online from a mobile device at similar or higher rates than other groups in the U.S., Smartphone interventions offer an opportunity to overcome obstacles to accessing resources and services that can be culturally informed and provide skills to improve symptom burden and HRQOL. This study aims to create and evaluate Mi Guía (My Guide), a culturally informed eHealth psychoeducational and psychosocial intervention for English or Spanish-speaking Hispanic women completing treatment for breast cancer. Mi Guía is grounded in evidence-based paradigms to improve our Primary Outcomes: Cancer-Related Symptom Burden and HRQOL and our Secondary Outcomes: usability and markers of Mi Guía use. We propose a two-phase study to develop our Smartphone-based intervention that can be disseminated to cancer survivors at a relatively low cost. We will use innovative methodology; MOST framework that will allow us to achieve both optimization and evaluation of Mi Guía by determining which single components or combination of components in Mi Guía affect our outcomes. Study components (one component on breast cancer psychoeducation, two psychosocial evidence-based components relevant to Hispanic BCS) will be paired with personal tele-coaching among BCS. Our Aims are: Aim 1:(Phase 1): Create Mi Guía, an eHealth intervention designed to improve cancer-related symptom burden and HRQOL. Aim 2: (Phase 2): Optimize components for Mi Guía through a 9-week randomized trial to evaluate three evidence- based intervention components relevant to Hispanic BCS. It is hypothesized that each single intervention component will improve cancer-related symptom burden and HRQOL and that combined intervention components will have a greater effect on our outcomes than single components.

改善症状负担和健康相关生活质量的电子健康干预 在完成积极治疗乳腺癌的西班牙裔妇女中， 摘要 拉美裔是美国人数最多、增长最快的少数民族，癌症是导致 心血管疾病是非裔美国人和非裔美国人死亡的主要原因， 西班牙裔白人（NHWs）西班牙裔人的5年癌症特异性生存率也明显较低 非西班牙裔白人（NHWs）美国的西班牙裔癌症患者也报告说， 癌症相关症状负担和健康相关生活质量（HRQOL）高于NHWs，即使在调整 社会经济因素。尽管如此，很少有随机干预研究专门针对 西班牙裔女性的癌症相关症状负担和HRQOL结局，特别是在 在积极治疗结束时，这是进行干预的关键时期，以提供技能和工具来帮助解决这一问题 过渡提供干预措施的创新方法，如智能手机技术， 这对患者群体来说是非常重要的。美国少数民族中普遍使用的智能手机为美国提供了一个 一个独特的机会，实施务实的技术和循证的心理社会干预， 克服了获得护理的一些障碍以及时间和后勤方面的限制。此外，鉴于 西班牙裔拥有智能手机，并以类似或更高的速度从移动终端在线寻求健康信息 比美国的其他群体，智能手机干预措施为克服障碍提供了机会， 获得可以在文化上知情的资源和服务，并提供改善症状的技能 负担和HRQOL。本研究旨在创建和评估Mi Guía（我的指南），一个文化信息化的电子健康 心理教育和心理社会干预的英语或西班牙语西班牙裔妇女完成 乳腺癌的治疗Mi Guía以循证范式为基础，以改善我们的初级 结局：癌症相关症状负担和HRQOL以及次要结局：可用性和 米圭亚使用的标记我们提出了一个两阶段的研究，以开发我们的智能手机为基础的干预， 可以以相对较低的成本传播给癌症幸存者。我们将采用创新方法; MOST 框架，这将使我们能够实现优化和评估Mi Guía通过确定哪一个单一的 Mi Guía中的组件或组件组合会影响我们的结果。研究组成部分（一个 关于乳腺癌心理教育的组成部分，两个基于证据的心理社会组成部分， 西班牙裔BCS）将与BCS中的个人远程教练配对。我们的目标是：目标1：（阶段1）：创建 Mi Guía是一项旨在改善癌症相关症状负担和HRQOL的电子健康干预措施。目标二： （第2阶段）：通过为期9周的随机试验优化Mi Guía的组件，以评估三个证据- 基于与西班牙裔BCS相关的干预成分。据推测，每一次干预 成分将改善癌症相关症状负担和HRQOL， 组成部分对我们的结果的影响将大于单一组成部分。