An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer

电子健康干预措施可改善完成乳腺癌积极治疗的西班牙裔女性的症状负担和健康相关的生活质量

• 批准号: 9163035
• 负责人: BETINA YANEZ
• 金额: $ 16.76万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9163035
• 关键词: Address; Advanced Malignant Neoplasm; Affect; African American; Aftercare; Age; Belief; Breast; Breast Cancer Education; Breast Cancer Treatment; Breast Cancer survivor; Cancer Etiology; Cancer Patient; Cancer Survivor; Cardiovascular Diseases; Cause of Death; Cellular Phone; Cessation of life; Chicago; Communication; Coping Skills; Data; Diagnosis; Distress; Evaluation; Evidence based intervention; Face; Health; Health Services Accessibility; Healthcare; Hispanics; Insurance Coverage; Intervention; Intervention Studies; Knowledge; Longitudinal Studies; Malignant Neoplasms; Methodology; Methods; Minority Groups; Names; Not Hispanic or Latino; Outcome; Participant; Patient Outcomes Assessments; Patients; Persons; Phase; Psychiatric Social Work; Randomized; Recruitment Activity; Reporting; Resources; Sample Size; Services; Socioeconomic Factors; Staging; Survivors; Symptoms; Technology; Testing; Time; Underserved Population; Woman; Work; abstracting; active method; base; breast cancer diagnosis; cancer diagnosis; cancer therapy; cost; critical period; depressive symptoms; design; eHealth; ethnic minority population; evidence base; experience; handheld mobile device; health equity; health related quality of life; improved; innovation; malignant breast neoplasm; novel; patient population; primary outcome; psychoeducation; psychoeducational; psychosocial; randomized trial; reduce symptoms; secondary outcome; skills; socioeconomics; stress management; survivorship; symptomatic improvement; therapy design; tool; usability

An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer Abstract Among Hispanics, the largest and fastest growing ethnic minority group in the U.S., cancer is the leading cause of death whereas cardiovascular disease is the leading cause of death for African Americans and non- Hispanic Whites (NHWs). Hispanics also experience substantially lower rates of 5-year cancer-specific survival relative to non–Hispanic Whites (NHWs). Hispanic cancer patients in the U.S. also report significantly worse cancer-related symptom burden and health-related quality of life (HRQOL) than NHWs, even after adjusting for socioeconomic factors. Despite this, very few randomized, intervention studies have specifically targeted cancer-related symptom burden and HRQOL outcomes among Hispanic women, especially during the period at the end of active treatment which is a critical period to intervene to provide skills and tools to assist with this transition. Innovative approaches to providing interventions such as Smartphone technology are especially important for this patient population. Ubiquitous Smartphone use among ethnic minorities in the US provide a unique opportunity to implement a pragmatic technology- and evidence-based psychosocial intervention that overcomes some access to care barriers as well as time and logistical constraints. Furthermore, given that Hispanics own Smartphones and seek health information online from a mobile device at similar or higher rates than other groups in the U.S., Smartphone interventions offer an opportunity to overcome obstacles to accessing resources and services that can be culturally informed and provide skills to improve symptom burden and HRQOL. This study aims to create and evaluate Mi Guía (My Guide), a culturally informed eHealth psychoeducational and psychosocial intervention for English or Spanish-speaking Hispanic women completing treatment for breast cancer. Mi Guía is grounded in evidence-based paradigms to improve our Primary Outcomes: Cancer-Related Symptom Burden and HRQOL and our Secondary Outcomes: usability and markers of Mi Guía use. We propose a two-phase study to develop our Smartphone-based intervention that can be disseminated to cancer survivors at a relatively low cost. We will use innovative methodology; MOST framework that will allow us to achieve both optimization and evaluation of Mi Guía by determining which single components or combination of components in Mi Guía affect our outcomes. Study components (one component on breast cancer psychoeducation, two psychosocial evidence-based components relevant to Hispanic BCS) will be paired with personal tele-coaching among BCS. Our Aims are: Aim 1:(Phase 1): Create Mi Guía, an eHealth intervention designed to improve cancer-related symptom burden and HRQOL. Aim 2: (Phase 2): Optimize components for Mi Guía through a 9-week randomized trial to evaluate three evidence- based intervention components relevant to Hispanic BCS. It is hypothesized that each single intervention component will improve cancer-related symptom burden and HRQOL and that combined intervention components will have a greater effect on our outcomes than single components.

改善症状负担和健康相关生活质量的电子健康干预 在完成乳腺癌积极治疗的西班牙裔女性中 摘要 在拉美裔美国人中，癌症是最大的，也是增长最快的少数民族群体 死因而心血管疾病是非裔美国人和非美国人的主要死因 西班牙裔白人(NHW)。拉美裔美国人患癌症的5年存活率也大大降低。 相对于非西班牙裔白人(NHW)。在美国，拉美裔癌症患者的病情也明显恶化 癌症相关症状负担和健康相关生活质量(HRQOL)高于卫生保健工作者，即使在调整 社会经济因素。尽管如此，很少有随机干预研究专门针对 拉美裔妇女的癌症相关症状负担和HRQOL结果，特别是在这一时期 在积极治疗结束时，这是干预的关键时期，以提供技能和工具来协助这一点 过渡。提供干预的创新方法，如智能手机技术，尤其是 对这群病人来说很重要。在美国少数民族中无处不在的智能手机使用为 实施基于技术和证据的实用心理社会干预的独特机会 克服了一些获得护理的障碍以及时间和后勤限制。此外，鉴于 拉美裔美国人拥有智能手机，并以类似或更高的费率从移动设备在线搜索健康信息 与美国的其他群体相比，智能手机干预提供了一个克服障碍的机会 获取可获得文化知识并提供改善症状的技能的资源和服务 负担和HRQOL。这项研究旨在创建和评估Mi Guía(我的指南)，一个了解文化知识的电子健康 为说英语或西班牙语的拉美裔妇女提供心理教育和心理社会干预 乳腺癌的治疗。Mi Guía以循证范式为基础，改善我们的初选 结果：癌症相关症状负担和HRQOL以及我们的次要结果：可用性和 Mi Guía使用的标记。我们提出了一项分两个阶段的研究，以开发基于智能手机的干预 可以以相对较低的成本传播给癌症幸存者。我们将使用创新的方法；大多数 该框架将使我们能够通过确定哪个单项来实现对Mi Guía的优化和评估 Mi Guía中的成分或成分组合影响我们的结果。研究组件(一个 关于乳腺癌心理教育的两个基于心理社会证据的组成部分 西班牙裔BCS)将与BCS中的个人远程教练配对。我们的目标是：目标1：(阶段1)：创建 Mi Guía，一项旨在改善癌症相关症状负担和HRQOL的电子健康干预措施。目标2： (第二阶段)：通过为期9周的随机试验优化Mi Guía的成分，以评估三项证据- 基于与西班牙裔BCS相关的干预组成部分。假设每一次干预 组份将改善癌症相关症状负担和HRQOL及联合干预 组成部分将比单一组成部分对我们的结果产生更大的影响。