9/11 Trauma and Toxicity in Childhood: Longitudinal Health and Behavioral Outcomes

9/11 童年创伤和毒性：纵向健康和行为结果

• 批准号: 9340135
• 负责人: Christina W. Hoven
• 金额: $ 59.96万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9340135
• 关键词: 11; Trauma; Toxicity; Childhood; Longitudinal

On 9/11, children who were residents of the World Trade Center area or students in local schools experienced a wide range of psychological traumas and of toxic exposures. To ensure their long term well- being of individuals exposed to 9/11 as children, it is imperative that we understand the longitudinal, lifetime effects that these traumatic and toxic exposures are having on their physical health and behavioral development. Yet the bulk of research has focused on those who were adults on 9/11. This research has furnished strong evidence linking 9/11 traumatic and toxic exposures (both on 9/11 and subsequently) to a wide range of subsequent adult psychiatric and physical disorders. Based on this research, much of it related to The World Trade Center Health Registry (WTCHR), we unfortunately can expect that youth who were directly exposed to 9/11 during sensitive periods in their physical and mental development will carry even greater and ongoing lifetime risks for a variety of behavioral and physical health difficulties. It is thus imperative to study these individuals over the long term, both to facilitate early intervention and amelioration for 9/11 exposed individuals, and to amortize this rare cohort to help us better understand the lifetime developmental impact of childhood trauma and toxicity for all the other children that may have been, or may yet become, so exposed. Yet, surprisingly, much less research has been done with those exposed to 9/11 as children. Our team, The Child Psychiatric Epidemiology Group (CPEG) has begun to fill in this gap with our own in depth mental health follow up evaluation of individuals in this sample in our funded Stress and Well Being (S&W) study. The S&W study followed N=1,000 individuals exposed to 9/11 as children and N=500, age and gender matched, unexposed Controls. It was focused on psychological trauma and psychiatric and behavioral outcomes, and produced concrete evidence for the ongoing developmental psychiatric and behavioral problems in this group, a decade after 9/11. We therefore now propose to conduct an expansion of the scope of this study by assessing these individuals for toxic as well as traumatic exposures and to follow their physical health (airway disorders and inflammatory processes) as well as their ongoing psychiatric (mental health, substance abuse) and behavioral (decision anomalies and high-risk behavior) outcomes. In addition we will be in a position to examine the interaction between traumatic and toxic exposures and the resulting comorbidities of physical and mental health issues. This will fill important knowledge gaps, resulting in valuable information to guide both psychiatric and general medical care for those children exposed to 9/11 and the ensuing toxicity, while simultaneously providing new information relevant for other youth exposed to other traumatic events.

9/11当天，世界贸易中心地区的居民或当地学校的学生 经历了广泛的心理创伤和中毒暴露。为了确保他们的长期健康- 作为儿童时期暴露于9/11事件的个人，我们必须理解纵向的、终身的 这些创伤和中毒暴露对他们的身体健康和行为的影响 发展。然而，大部分研究都集中在那些在9/11事件中已经成年的人。 提供了强有力的证据，将9/11创伤和中毒暴露(包括9/11和随后的)与 随后出现的各种成人精神和身体障碍。基于这项研究，其中很大一部分与 到世界贸易中心卫生注册中心(WTCHR)，不幸的是，我们可以预料到 在他们身心发展的敏感期直接暴露在9/11事件中会带来甚至 各种行为和身体健康困难的更大的和持续的终生风险。因此，这是势在必行的 对这些人进行长期研究，以促进9/11事件的早期干预和改善 暴露的个体，并摊销这一罕见的队列，以帮助我们更好地了解终身发育 童年创伤和中毒对所有其他可能已经或可能成为这样的儿童的影响 暴露了。然而，令人惊讶的是，对儿童时期接触过9/11事件的人进行的研究要少得多。我们的 团队，儿童精神流行病学小组(CPEG)已经开始用我们自己的小组来填补这一空白 本研究资助的压力与幸福感研究样本中个体的心理健康追踪评估(S，W) 学习。S和W的这项研究跟踪了N=1,000名儿童时期遭受9/11袭击的人，以及N=500名年龄和性别 配对的、未暴露的对照组。它的重点是心理创伤以及精神和行为 结果，并提供了正在进行的精神和行为发育的具体证据 这个群体的问题，在9·11事件之后的十年。因此，我们现在建议扩大范围 通过评估这些人的中毒和创伤暴露，并跟踪他们的身体状况 健康(呼吸道障碍和炎症过程)以及他们正在进行的精神健康(精神健康， 药物滥用)和行为(决策异常和高风险行为)结果。此外，我们还将 能够研究创伤和中毒暴露以及由此产生的共病之间的相互作用 身体和精神健康问题。这将填补重要的知识空白，从而产生有价值的信息 指导那些暴露在9/11事件和随之而来的毒性中的儿童的精神和一般医疗护理， 同时提供与其他遭受其他创伤事件的青年有关的新信息。