Summer Undergraduate Research Experiences in Genomic Medicine (SURE-GM)

摘要 增加从事遗传学和生物医学研究的生物医学科学家多样性的新战略 基因组研究是人类健康和基因组持续改善的关键目标。 医药。这一目标在南方腹地尤为重要，在该地区，有大量 有一部分人口经历了医疗保健差距，那里有很大一部分非洲人-- 美国人口，以及许多来自优势和劣势的学生 背景-在阿拉巴马州州立大学系统接受本科教育，或 阿拉巴马州历史上的黑人学院或大学(HBCU)。 此R25应用程序计划利用并构建位于 阿拉巴马大学伯明翰分校(UAB)和哈德森·阿尔法生物技术研究所 开发Sure-GM，这是一个为HBCU本科生量身定做的连续两个暑期课程 将为他们提供必要的技能、曝光率和经验的学生 参与并对基因组专业的毕业生和/或专业培训做出有意义的贡献 科学。每年将从阿拉巴马州HBCU确定和招募12名学者作为 后起之秀。这些学者将在哈德逊阿尔法大学度过他们的第一个夏天，从事 基础研究技能，他们在UAB的第二个夏天从事指导性研究，以及 将在中间的学年期间参加“一到二”的延续计划。一个 将制定强有力的评估和审查流程，以实现实时反馈和 评估。这些努力将导致代表不足的学生更多地参与 从事生物医学工作的科学家和内科科学家更加多样化 生物医学研究，以及更多地认识到基因组医学在 科学和社会。

Summary New strategies to increase the diversity of biomedical scientists engaged in genetic and genomic research is a critical goal for continued improvements in human health and genomic medicine. This goal is especially important in the Deep South, a region in which a large proportion of the population experiences health care disparities, where there is a large African- American population, and where many students—from both advantaged and disadvantaged backgrounds—pursue undergraduate education in the Alabama state university system, or in historically black colleges or universities (HBCUs) within Alabama. This R25 application proposes to leverage and build on the collaborative environment at the University of Alabama, Birmingham (UAB) and the HudsonAlpha Institute for Biotechnology to develop SURE-GM, a two consecutive summer program tailored for HBCU undergraduate students that will equip and provide them with the necessary skills, exposures, and experiences to participate and contribute meaningfully to graduate and/or professional training in genomic sciences. Twelve scholars per year will be identified and recruited from Alabama HBCUs as rising juniors. The scholars will spend their first summer at HudsonAlpha engaged in training for foundational research skills, their second summer at UAB engaged in mentored research, and will participate in a "One to Two" continuity program during the intervening academic year. A robust assessment and review process will be developed that allows for real-time feedback and evaluation. These efforts will lead to greater participation of underrepresented students in the biomedical workforce, greater diversity of scientists and physician scientists engaged in biomedical research, and greater appreciation of the roles and potential of genomic medicine in science and society.